In this issue of Clinics in Perinatology, guest editors Drs. Sagori Mukhopadhyay and Karen M. Puopolo bring their considerable expertise to the topic of Perinatal and Neonatal Infections. Top experts review the fundamentals of neonatal infections and discuss the changing landscape of infectious disease and its management. Articles cover disease epidemiology, infection-related issues that have come into focus as neonatal practice evolves, the use of genomics to gain understanding of late-onset sepsis pathogenesis, consideration of circadian biology in infection transmission and acquisition, and more.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. CME Accreditation Page - p. xii 8. Foreword - p. xv 9. Preface - p. xix 10. Core Concepts - p. xxii 11. Keeping Your Neonatal Intensive Care Unit Clean: The Hospital Environment as a Potential Source of Health Care-Associated Infections - p. 1 12. Neonatal Early-Onset Sepsis: Epidemiology, Microbiology, and Controversies in Practice - p. 15 13. Late-Onset Sepsis: Epidemiology, Microbiology, and Controversies in Practice - p. 33 14. Neonatal Invasive Fungal Infections: Epidemiology, Microbiology, and Controversies in Practice - p. 47 15. Pharmacokinetic and Pharmacodynamic Approaches to Optimize Antibiotic Use in Neonates - p. 67 16. Emerging Issues - p. 86 17. Probiotics and the Risk of Infection - p. 87 18. Transplacental Antibodies: Role of Maternal Vaccines and Immunity - p. 101 19. Neonatal Cytomegalovirus Infection: Advocacy, Legislation, and Changing Practice - p. 115 20. Re-Thinking the Norms of Antibiotic Prescribing in the Neonatal Intensive Care Unit - p. 133 21. Future Perspectives - p. 146 22. Role of the Microbiome in Neonatal Infection: Pathogenesis and Implications for Management - p. 147 23. Machine Learning Models as Early Warning Systems for Neonatal Infection - p. 167 24. Circadian Rhythms, Immune Regulation, and the Risk for Sepsis: Circadian Rhythms and Neonatal Care - p. 185
In this issue of Clinics in Perinatology, guest editors Drs. Sagori Mukhopadhyay and Karen M. Puopolo bring their considerable expertise to the topic of Perinatal and Neonatal Infections. Top experts review the fundamentals of neonatal infections and discuss the changing landscape of infectious disease and its management. Articles cover disease epidemiology, infection-related issues that have come into focus as neonatal practice evolves, the use of genomics to gain understanding of late-onset sepsis pathogenesis, consideration of circadian biology in infection transmission and acquisition, and more.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. CME Accreditation Page - p. xii 8. Foreword - p. xv 9. Preface - p. xix 10. Core Concepts - p. xxii 11. Keeping Your Neonatal Intensive Care Unit Clean: The Hospital Environment as a Potential Source of Health Care-Associated Infections - p. 1 12. Neonatal Early-Onset Sepsis: Epidemiology, Microbiology, and Controversies in Practice - p. 15 13. Late-Onset Sepsis: Epidemiology, Microbiology, and Controversies in Practice - p. 33 14. Neonatal Invasive Fungal Infections: Epidemiology, Microbiology, and Controversies in Practice - p. 47 15. Pharmacokinetic and Pharmacodynamic Approaches to Optimize Antibiotic Use in Neonates - p. 67 16. Emerging Issues - p. 86 17. Probiotics and the Risk of Infection - p. 87 18. Transplacental Antibodies: Role of Maternal Vaccines and Immunity - p. 101 19. Neonatal Cytomegalovirus Infection: Advocacy, Legislation, and Changing Practice - p. 115 20. Re-Thinking the Norms of Antibiotic Prescribing in the Neonatal Intensive Care Unit - p. 133 21. Future Perspectives - p. 146 22. Role of the Microbiome in Neonatal Infection: Pathogenesis and Implications for Management - p. 147 23. Machine Learning Models as Early Warning Systems for Neonatal Infection - p. 167 24. Circadian Rhythms, Immune Regulation, and the Risk for Sepsis: Circadian Rhythms and Neonatal Care - p. 185