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Synthesizing the expertise of the world’s most respected authorities on these challenging conditions, Petz & Garratty's Immune Hemolytic Anemias, 3rd Edition, offers up-to-date, comprehensive coverage for today’s clinical hematologists, pathologists, transfusion medicine fellows, residents, and laboratory healthcare professionals. This extensively revised text examines the selection and interpretation of laboratory tests as well as all of today's best diagnostic and treatment methods for the full range of immune hemolytic anemias. Continuing the tradition of excellence begun by Drs. Lawrence D. Petz and George Garratty, this fully revised edition, now meticulously updated and edited by Drs. Waseem Anani and Gregory Denomme, remains the foremost resource on immune hemolytic anemias.

  • Provides critical information to help hematologists and other clinicians become more familiar with diagnosis and treatment of immune hemolytic anemias, and develop the rapid, informed decision-making skills that these conditions often demand
  • Includes both foundational knowledge and clinical guidance for diagnosis
  • Highlights laboratory features of individual disease states and provides guidance on tests used to determine differential diagnoses
  • Provides recommendations for navigating difficult cases where diagnostic testing and/or clinical presentation are unclear
  • Covers key topics including drug-induced hemolytic anemia, suppressed erythropoiesis in HDFN, blood transfusion in autoimmune hemolytic anemias, transplantation and autoimmune hemolytic anemias, with two new chapters on monoclonocal antibody therapies affecting red blood cells, and pediatric immune hemolytic anemia
  • Any additional digital ancillary content may publish up to 6 weeks following the publication date

1. Introduction - p. 289 2. The Immune Response to Drugs - p. 297 3. Suggested Mechanisms of Drug-induced Hemolytic Anemia and/or Positive Direct Antiglobulin Test - p. 312 4. Serologic and Clinical Findings Associated With Drug-Induced Immune Hemolytic Anemia - p. 316 5. Drugs Associated With Each Category of Drug-Induced Immune Hemolytic Anemia - p. 318 6. Cephalosporin Antibodies - p. 320 7. Piperacillin Antibodies - p. 324 8. Methyldopa Antibodies - p. 325 9. Autoimmune Hemolytic Anemia Caused by Drugs Other Than Methyldopa - p. 331 10. Serologic Methods for Investigating Drug-Induced Immune Hemolytic Anemia - p. 339 11. Preparation of Drug Solutions - p. 341 12. Preparation of Drug-Treated Red Blood Cells - p. 343 13. Use of Carbodiimide to Couple Drugs to Red Blood Cells, - p. 343 14. Testing of Drug-Treated Red Blood Cells - p. 344 15. Drug (Hapten) Inhibition - p. 345 16. Detection of Antibodies to Drugs by the Immune Complex Method - p. 347 17. Questions - p. 348 18. Answers - p. 351 19. References - p. 353 20. 9. Biological (Monoclonal Antibody) Therapies Affecting Red Blood Cells - p. 364 21. 10. Unusual Aspects of Acquired Immune Hemolytic Anemias - p. 378 22. Chapter Outline - p. 378 23. Autoimmune Hemolytic Anemia With a Negative Direct Antiglobulin Test - p. 379 24. Development of Red Blood Cell Autoantibodies and Autoimmune Hemolytic Anemia Following Transfusion - p. 402 25. Autoimmune Hemolytic Anemia During Pregnancy - p. 408 26. Familial Autoimmune Hemolytic Anemia - p. 414 27. Cardiac Surgery and Cold Autoantibodies - p. 415 28. Differentiating Delayed Hemolytic Transfusion Reactions From Autoimmune Hemolytic Anemia - p. 418 29. Bystander Immune Hemolysis - p. 420 30. References - p. 430 31. 11. Blood Transfusion in Autoimmune Hemolytic Anemias - p. 443 32. 12. Management of Autoimmune Hemolytic Anemias - p. 472 33. 13. Immune Hemolysis Associated With Transplantation - p. 531 34. 14. Hemolytic Disease of the Fetus and Newborn - p. 584 35. 15. Pediatric Immune Hemolytic Anemia - p. 620 36. 16. Hemolytic Transfusion Reactions - p. 635 37. Index - p. 669

Descripcion
Descripción

Synthesizing the expertise of the world’s most respected authorities on these challenging conditions, Petz & Garratty's Immune Hemolytic Anemias, 3rd Edition, offers up-to-date, comprehensive coverage for today’s clinical hematologists, pathologists, transfusion medicine fellows, residents, and laboratory healthcare professionals. This extensively revised text examines the selection and interpretation of laboratory tests as well as all of today's best diagnostic and treatment methods for the full range of immune hemolytic anemias. Continuing the tradition of excellence begun by Drs. Lawrence D. Petz and George Garratty, this fully revised edition, now meticulously updated and edited by Drs. Waseem Anani and Gregory Denomme, remains the foremost resource on immune hemolytic anemias.

  • Provides critical information to help hematologists and other clinicians become more familiar with diagnosis and treatment of immune hemolytic anemias, and develop the rapid, informed decision-making skills that these conditions often demand
  • Includes both foundational knowledge and clinical guidance for diagnosis
  • Highlights laboratory features of individual disease states and provides guidance on tests used to determine differential diagnoses
  • Provides recommendations for navigating difficult cases where diagnostic testing and/or clinical presentation are unclear
  • Covers key topics including drug-induced hemolytic anemia, suppressed erythropoiesis in HDFN, blood transfusion in autoimmune hemolytic anemias, transplantation and autoimmune hemolytic anemias, with two new chapters on monoclonocal antibody therapies affecting red blood cells, and pediatric immune hemolytic anemia
  • Any additional digital ancillary content may publish up to 6 weeks following the publication date

1. Introduction - p. 289 2. The Immune Response to Drugs - p. 297 3. Suggested Mechanisms of Drug-induced Hemolytic Anemia and/or Positive Direct Antiglobulin Test - p. 312 4. Serologic and Clinical Findings Associated With Drug-Induced Immune Hemolytic Anemia - p. 316 5. Drugs Associated With Each Category of Drug-Induced Immune Hemolytic Anemia - p. 318 6. Cephalosporin Antibodies - p. 320 7. Piperacillin Antibodies - p. 324 8. Methyldopa Antibodies - p. 325 9. Autoimmune Hemolytic Anemia Caused by Drugs Other Than Methyldopa - p. 331 10. Serologic Methods for Investigating Drug-Induced Immune Hemolytic Anemia - p. 339 11. Preparation of Drug Solutions - p. 341 12. Preparation of Drug-Treated Red Blood Cells - p. 343 13. Use of Carbodiimide to Couple Drugs to Red Blood Cells, - p. 343 14. Testing of Drug-Treated Red Blood Cells - p. 344 15. Drug (Hapten) Inhibition - p. 345 16. Detection of Antibodies to Drugs by the Immune Complex Method - p. 347 17. Questions - p. 348 18. Answers - p. 351 19. References - p. 353 20. 9. Biological (Monoclonal Antibody) Therapies Affecting Red Blood Cells - p. 364 21. 10. Unusual Aspects of Acquired Immune Hemolytic Anemias - p. 378 22. Chapter Outline - p. 378 23. Autoimmune Hemolytic Anemia With a Negative Direct Antiglobulin Test - p. 379 24. Development of Red Blood Cell Autoantibodies and Autoimmune Hemolytic Anemia Following Transfusion - p. 402 25. Autoimmune Hemolytic Anemia During Pregnancy - p. 408 26. Familial Autoimmune Hemolytic Anemia - p. 414 27. Cardiac Surgery and Cold Autoantibodies - p. 415 28. Differentiating Delayed Hemolytic Transfusion Reactions From Autoimmune Hemolytic Anemia - p. 418 29. Bystander Immune Hemolysis - p. 420 30. References - p. 430 31. 11. Blood Transfusion in Autoimmune Hemolytic Anemias - p. 443 32. 12. Management of Autoimmune Hemolytic Anemias - p. 472 33. 13. Immune Hemolysis Associated With Transplantation - p. 531 34. 14. Hemolytic Disease of the Fetus and Newborn - p. 584 35. 15. Pediatric Immune Hemolytic Anemia - p. 620 36. 16. Hemolytic Transfusion Reactions - p. 635 37. Index - p. 669

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