Pharmacological Advances in Central Nervous System Stimulants, Volume 99 in the Mechanisms, Therapeutic Uses, and Abuse of Stimulants series, showcases recent pharmacological progress investigating both therapeutic (ADHD, binge-eating and narcolepsy) and abuse aspects of a number of stimulants, some of which are long-standing (amphetamines, cocaine and nicotine) while others are emerging (cathinones). Specific chapters in this new release include Transgenerational Epigenetic Inheritance of Phenotypes Associated with Parental Exposure to Drugs of Abuse, Dysregulation Of Brain Cholesterol Homeostasis by Psychostimulants, Modeling Methamphetamine Use Disorder in Mammals: Sex Differences in Behavioral Consequences and Gene Expression, and much more.
Additional sections focus on Second Generation Stimulants – Pharmacological and Clinical Advances in The Treatment of ADHD And Binge-eating disorder, Pharmacology Of Stimulant – Opioid Co-Use, Role Of Age and Sex in Determining the Risk For Adverse Consequences Following Exposure To Amphetamines, Modafinil, An Atypical CNS Stimulant, Modulators Of Nicotine Reward-Related and Reinforcement-Related Behaviors, Methamphetamine Effects on Peripheral Immune System, Post-Translational Mechanisms in Neurotransmitter Efflux, The Many Enigmas of Nicotine, Genetic Variation in The Neuregulin-Erbb Signaling Pathway And Substance Use Disorders, Pharmacology And Neurotoxicology of Synthetic Cathinones, and more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. Obituary: S.J. Enna, PhDDecember 19, 1944–June 15, 2023 - p. iii 8. Chapter One: Post-translational mechanisms in psychostimulant-induced neurotransmitter efflux - p. 2 9. Chapter Two: Cholesterol modulation of interactions between psychostimulants and dopamine transporters - p. 31 10. Chapter Three: The pharmacology and neurotoxicology of synthetic cathinones - p. 62 11. Chapter Four: Structural and functional perspectives on interactions between synthetic cathinones and monoamine transporters - p. 84 12. Chapter Five: The role of sex and drug use during adolescence in determining the risk for adverse consequences of amphetamines - p. p145 13. Chapter Six: Modeling methamphetamine use disorder in mammals: Sex differences in behavioral, biochemical, and transcriptional consequences - p. p144 14. Chapter Seven: Epigenetic inheritance of phenotypes associated with parental exposure to cocaine - p. p170 15. Chapter Eight: Immunity on ice: The impact of methamphetamine on peripheral immunity - p. 218 16. Chapter Nine: Stimulant prodrugs: A pharmacological and clinical assessment of their role in treating ADHD and binge-eating disorder - p. 252 17. Chapter Ten: Modafinil, an atypical CNS stimulant? - p. 288 18. Chapter Eleven: The many enigmas of nicotine - p. 328 19. Chapter Twelve: Modulators of nicotine reward and reinforcement - p. 356 20. Chapter Thirteen: Nicotine use disorder and Neuregulin 3: Opportunities for precision medicine - p. 388
Pharmacological Advances in Central Nervous System Stimulants, Volume 99 in the Mechanisms, Therapeutic Uses, and Abuse of Stimulants series, showcases recent pharmacological progress investigating both therapeutic (ADHD, binge-eating and narcolepsy) and abuse aspects of a number of stimulants, some of which are long-standing (amphetamines, cocaine and nicotine) while others are emerging (cathinones). Specific chapters in this new release include Transgenerational Epigenetic Inheritance of Phenotypes Associated with Parental Exposure to Drugs of Abuse, Dysregulation Of Brain Cholesterol Homeostasis by Psychostimulants, Modeling Methamphetamine Use Disorder in Mammals: Sex Differences in Behavioral Consequences and Gene Expression, and much more.
Additional sections focus on Second Generation Stimulants – Pharmacological and Clinical Advances in The Treatment of ADHD And Binge-eating disorder, Pharmacology Of Stimulant – Opioid Co-Use, Role Of Age and Sex in Determining the Risk For Adverse Consequences Following Exposure To Amphetamines, Modafinil, An Atypical CNS Stimulant, Modulators Of Nicotine Reward-Related and Reinforcement-Related Behaviors, Methamphetamine Effects on Peripheral Immune System, Post-Translational Mechanisms in Neurotransmitter Efflux, The Many Enigmas of Nicotine, Genetic Variation in The Neuregulin-Erbb Signaling Pathway And Substance Use Disorders, Pharmacology And Neurotoxicology of Synthetic Cathinones, and more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. Obituary: S.J. Enna, PhDDecember 19, 1944–June 15, 2023 - p. iii 8. Chapter One: Post-translational mechanisms in psychostimulant-induced neurotransmitter efflux - p. 2 9. Chapter Two: Cholesterol modulation of interactions between psychostimulants and dopamine transporters - p. 31 10. Chapter Three: The pharmacology and neurotoxicology of synthetic cathinones - p. 62 11. Chapter Four: Structural and functional perspectives on interactions between synthetic cathinones and monoamine transporters - p. 84 12. Chapter Five: The role of sex and drug use during adolescence in determining the risk for adverse consequences of amphetamines - p. p145 13. Chapter Six: Modeling methamphetamine use disorder in mammals: Sex differences in behavioral, biochemical, and transcriptional consequences - p. p144 14. Chapter Seven: Epigenetic inheritance of phenotypes associated with parental exposure to cocaine - p. p170 15. Chapter Eight: Immunity on ice: The impact of methamphetamine on peripheral immunity - p. 218 16. Chapter Nine: Stimulant prodrugs: A pharmacological and clinical assessment of their role in treating ADHD and binge-eating disorder - p. 252 17. Chapter Ten: Modafinil, an atypical CNS stimulant? - p. 288 18. Chapter Eleven: The many enigmas of nicotine - p. 328 19. Chapter Twelve: Modulators of nicotine reward and reinforcement - p. 356 20. Chapter Thirteen: Nicotine use disorder and Neuregulin 3: Opportunities for precision medicine - p. 388
