Women’s healthcare regarding polycystic ovarian syndrome remains challenging. Patients often go from one specialist to another trying to fully understand and management the disorder. Women often go years before a diagnosis, seeing three or more doctors before a confirmed diagnosis. Polycystic Ovarian Syndrome: Challenging Issues in the Modern Era of Individualized Medicine brings together multiple medical disciplines to improve the care of women with PCOS. Such a multidisciplinary clinical and scientific approach integrates obstetrics and gynecology, pediatric and medical endocrinology, internal medicine, genetics, psychology and laboratory medicine into relevant translational clinical and scientific discussions that update both the scientific understanding of PCOS and the diagnosis and management of all aspects of the syndrome. The impact of PCO on the onset of puberty is subdivided in sub sections to get a better understanding of this condition and the management at different stages in a woman’s life.
1. Polycystic Ovary Syndrome - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Dedication - p. Page v 7. Contributors - p. Page v 8. Author biography - p. Page vii 9. List of Illustrations - p. Page ix 10. List of Tables - p. Page x 11. Chapter 1 : Defining PCOS: A syndrome with an intrinsic heterogeneous nature - p. Page x 12. Chapter 2 : Secondary PCOS: Well-defined causes, leading to the PCOS phenotype - p. Page 11 13. Chapter 3 : Developmental origins of polycystic ovary syndrome: Everything starts in utero - p. Page 21 14. Chapter 4 : The multifarious role of insulin in PCOS: From pathophysiology to therapeutic management - p. Page 37 15. Chapter 5 : The pathogenic role of androgen excess in PCOS - p. Page 51 16. Chapter 6 : Intrinsic abnormalities of adipose tissue and adipose tissue dysfunction in PCOS - p. Page 69 17. Chapter 7 : Diet and exercise in the management of PCOS: Starting from the basics - p. Page 92 18. Chapter 8 : Targeting metabolism in the management of PCOS: Metformin and beyond - p. Page 114 19. Chapter 9 : Combined oral contraceptives: Why, when, where? - p. Page 129 20. Chapter 10 : Targeting infertility in PCOS: Unfolding “Ariadne's thread” - p. Page 152 21. Chapter 11 : Inositols and other supplements in the management of PCOS - p. Page 161 22. Chapter 12 : Polycystic ovary syndrome and nonalcoholic fatty liver disease - p. Page 182 23. Chapter 13 : Cardiometabolic risk in women with PCOS - p. Page 216 24. Chapter 14 : Endocrine-disrupting chemicals and PCOS: A novel contributor in the etiology of the syndrome - p. Page 223 25. Chapter 15 : Long-term health in women of age more than 40years with polycystic ovary syndrome - p. Page 240 26. Chapter 16 : Vitamin D metabolism in polycystic ovary syndrome (PCOS) - p. Page 283 27. Chapter 17 : The challenging role of antiandrogens in the management of polycystic ovary syndrome - p. Page 293 28. Chapter 18 : PCOS in adolescence: Pathophysiology, diagnostic challenges, and therapeutic controversies - p. Page 313 29. Chapter 19 : Obstructive sleep apnea and polycystic ovary syndrome: Clinical interactions and underlying pathophysiology - p. Page 321 30. Index - p. Page 339
Women’s healthcare regarding polycystic ovarian syndrome remains challenging. Patients often go from one specialist to another trying to fully understand and management the disorder. Women often go years before a diagnosis, seeing three or more doctors before a confirmed diagnosis. Polycystic Ovarian Syndrome: Challenging Issues in the Modern Era of Individualized Medicine brings together multiple medical disciplines to improve the care of women with PCOS. Such a multidisciplinary clinical and scientific approach integrates obstetrics and gynecology, pediatric and medical endocrinology, internal medicine, genetics, psychology and laboratory medicine into relevant translational clinical and scientific discussions that update both the scientific understanding of PCOS and the diagnosis and management of all aspects of the syndrome. The impact of PCO on the onset of puberty is subdivided in sub sections to get a better understanding of this condition and the management at different stages in a woman’s life.
1. Polycystic Ovary Syndrome - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Dedication - p. Page v 7. Contributors - p. Page v 8. Author biography - p. Page vii 9. List of Illustrations - p. Page ix 10. List of Tables - p. Page x 11. Chapter 1 : Defining PCOS: A syndrome with an intrinsic heterogeneous nature - p. Page x 12. Chapter 2 : Secondary PCOS: Well-defined causes, leading to the PCOS phenotype - p. Page 11 13. Chapter 3 : Developmental origins of polycystic ovary syndrome: Everything starts in utero - p. Page 21 14. Chapter 4 : The multifarious role of insulin in PCOS: From pathophysiology to therapeutic management - p. Page 37 15. Chapter 5 : The pathogenic role of androgen excess in PCOS - p. Page 51 16. Chapter 6 : Intrinsic abnormalities of adipose tissue and adipose tissue dysfunction in PCOS - p. Page 69 17. Chapter 7 : Diet and exercise in the management of PCOS: Starting from the basics - p. Page 92 18. Chapter 8 : Targeting metabolism in the management of PCOS: Metformin and beyond - p. Page 114 19. Chapter 9 : Combined oral contraceptives: Why, when, where? - p. Page 129 20. Chapter 10 : Targeting infertility in PCOS: Unfolding “Ariadne's thread” - p. Page 152 21. Chapter 11 : Inositols and other supplements in the management of PCOS - p. Page 161 22. Chapter 12 : Polycystic ovary syndrome and nonalcoholic fatty liver disease - p. Page 182 23. Chapter 13 : Cardiometabolic risk in women with PCOS - p. Page 216 24. Chapter 14 : Endocrine-disrupting chemicals and PCOS: A novel contributor in the etiology of the syndrome - p. Page 223 25. Chapter 15 : Long-term health in women of age more than 40years with polycystic ovary syndrome - p. Page 240 26. Chapter 16 : Vitamin D metabolism in polycystic ovary syndrome (PCOS) - p. Page 283 27. Chapter 17 : The challenging role of antiandrogens in the management of polycystic ovary syndrome - p. Page 293 28. Chapter 18 : PCOS in adolescence: Pathophysiology, diagnostic challenges, and therapeutic controversies - p. Page 313 29. Chapter 19 : Obstructive sleep apnea and polycystic ovary syndrome: Clinical interactions and underlying pathophysiology - p. Page 321 30. Index - p. Page 339
