Posttraumatic Epilepsy: Basic and Clinical Aspects provides a synthesized resource on recent basic and clinical science developments in the field of posttraumatic epilepsy. The book provides a clear understanding of the history of studies of posttraumatic epilepsy and the military and civilian data regarding risk of epilepsy after head trauma. It also covers the basic science of animal models of head injury and the necessary and sufficient changes that must occur to generate epilepsy after head trauma. The authors also explore novel therapeutic approaches to prevent posttraumatic epilepsy.
It is written for basic and clinical researchers in neuroscience, as well as clinicians treating patients with epilepsy.
1. Posttraumatic Epilepsy - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iv 5. Copyright - p. Page v 6. Dedication - p. Page vi 7. Preface - p. Page vii 8. Acknowledgments - p. Page viii 9. List of Illustrations - p. Page ix 10. List of Tables - p. Page x 11. Chapter 1 : History of posttraumatic epilepsy - p. Page x 12. Chapter 2 : Epidemiology of posttraumatic epilepsy - p. Page 24 13. Chapter 3 : Neuropathology of posttraumatic epilepsy - p. Page 39 14. Chapter 4 : Clinical trials of agents to prevent posttraumatic epilepsy - p. Page 64 15. Chapter 5 : Surgical treatment of posttraumatic epilepsy - p. Page 71 16. Chapter 6 : Animal models of traumatic brain injury - p. Page 89 17. Chapter 7 : Incidence of posttraumatic epilepsy in animal models of traumatic brain injury - p. Page 98 18. Chapter 8 : Cellular and molecular changes in animal models of posttraumatic epilepsy - p. Page 111 19. Chapter 9 : Blood-brain barrier disruption and posttraumatic epilepsy - p. Page 118 20. Chapter 10 : Inflammation and posttraumatic epilepsy - p. Page 133 21. Chapter 11 : Biomarkers and treatment trials in animal models to prevent posttraumatic epilepsy - p. Page 148 22. Chapter 12 : Therapeutic targets and future directions - p. Page 165 23. Index - p. Page 177
Posttraumatic Epilepsy: Basic and Clinical Aspects provides a synthesized resource on recent basic and clinical science developments in the field of posttraumatic epilepsy. The book provides a clear understanding of the history of studies of posttraumatic epilepsy and the military and civilian data regarding risk of epilepsy after head trauma. It also covers the basic science of animal models of head injury and the necessary and sufficient changes that must occur to generate epilepsy after head trauma. The authors also explore novel therapeutic approaches to prevent posttraumatic epilepsy.
It is written for basic and clinical researchers in neuroscience, as well as clinicians treating patients with epilepsy.
1. Posttraumatic Epilepsy - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iv 5. Copyright - p. Page v 6. Dedication - p. Page vi 7. Preface - p. Page vii 8. Acknowledgments - p. Page viii 9. List of Illustrations - p. Page ix 10. List of Tables - p. Page x 11. Chapter 1 : History of posttraumatic epilepsy - p. Page x 12. Chapter 2 : Epidemiology of posttraumatic epilepsy - p. Page 24 13. Chapter 3 : Neuropathology of posttraumatic epilepsy - p. Page 39 14. Chapter 4 : Clinical trials of agents to prevent posttraumatic epilepsy - p. Page 64 15. Chapter 5 : Surgical treatment of posttraumatic epilepsy - p. Page 71 16. Chapter 6 : Animal models of traumatic brain injury - p. Page 89 17. Chapter 7 : Incidence of posttraumatic epilepsy in animal models of traumatic brain injury - p. Page 98 18. Chapter 8 : Cellular and molecular changes in animal models of posttraumatic epilepsy - p. Page 111 19. Chapter 9 : Blood-brain barrier disruption and posttraumatic epilepsy - p. Page 118 20. Chapter 10 : Inflammation and posttraumatic epilepsy - p. Page 133 21. Chapter 11 : Biomarkers and treatment trials in animal models to prevent posttraumatic epilepsy - p. Page 148 22. Chapter 12 : Therapeutic targets and future directions - p. Page 165 23. Index - p. Page 177
