Part of the in-depth and practical Pattern Recognition series, Practical Surgical Soft Tissue Pathology, 2nd Edition, helps you arrive at an accurate diagnosis by using a proven pattern-based approach. Leading diagnosticians guide you through the most common patterns seen in soft tissue pathology, applying appropriate immunohistochemistry and molecular testing, avoiding pitfalls, and making the best diagnosis. High-quality illustrations capture key morphologic patterns for a full range of common and rare tumor types, and a "visual index" at the beginning of the book directs you to the exact location of in-depth diagnostic guidance.
1. 1 Introduction - p. 1 2. 2 Biologic Potential, Grading, Staging, and Reporting of Sarcomas - p. 9 3. 3 Spindle Cell Tumors of Adults - p. 15 4. General Concepts - p. 16 5. Nonmesenchymal Neoplasms With Spindle Cell Cytomorphology - p. 18 6. Malignant Mesothelioma - p. 19 7. Nodular Fasciitis and Similar Pseudosarcomatous Myofibroblastic Lesions - p. 20 8. Myofibroma and Myopericytoma - p. 27 9. Phosphaturic Mesenchymal Tumor - p. 30 10. Myofibroblastoma and Variants - p. 31 11. Fibroma - p. 33 12. Calcifying Fibrous Tumor - p. 37 13. Angiofibroma of Soft Tissue - p. 37 14. Fibrous Histiocytoma and Variants - p. 39 15. Solitary Fibrous Tumor and Variants - p. 40 16. Fibromatoses - p. 46 17. Spindle Cell Lipoma - p. 50 18. Atypical Spindle Cell Lipomatous Tumor - p. 50 19. Schwannoma and Variants - p. 51 20. Neurofibroma - p. 57 21. Perineurioma - p. 61 22. Ganglioneuroma - p. 63 23. Benign Smooth Muscle Tumors - p. 64 24. Leiomyosarcoma - p. 66 25. Epstein-Barr Virus–Associated Smooth Muscle Neoplasm - p. 68 26. Lymphangiomyoma and Lymphangiomyomatosis - p. 68 27. Angiomatoid Fibrous Histiocytoma - p. 68 28. Synovial Sarcoma - p. 72 29. Malignant Peripheral Nerve Sheath Tumor - p. 76 30. Biphenotypic Sinonasal Sarcoma - p. 79 31. Sarcomas With Fibroblastic Differentiation - p. 81 32. Low-Grade Myofibroblastic Sarcoma - p. 84 33. Spindle Cell Rhabdomyosarcoma - p. 86 34. Clear Cell Sarcoma - p. 87 35. Pseudomyogenic Hemangioendothelioma - p. 89 36. Unclassified Spindle Cell Sarcomas - p. 92 37. References - p. 92 38. 4 Pediatric Spindle Cell Tumors - p. 101 39. 5 Tumors With Myxoid Stroma - p. 135 40. 6 Epithelioid and Epithelial-Like Tumors - p. 165 41. Approach to the Diagnosis of Epithelioid Tumors of Soft Tissue - p. 165 42. Epithelioid Hemangioma - p. 168 43. Glomus Tumor - p. 171 44. Myoepithelioma/Mixed Tumor/Myoepithelial Carcinoma of Soft Tissue - p. 173 45. PEComa of Soft Tissue - p. 177 46. Adult-Type Rhabdomyoma - p. 181 47. Epithelioid Schwannoma - p. 182 48. Granular Cell Tumor - p. 182 49. Sclerosing Perineurioma - p. 184 50. Extracranial Meningioma - p. 184 51. Ossifying Fibromyxoid Tumor - p. 185 52. Ependymoma of Soft Tissue - p. 185 53. Alveolar Soft Part Sarcoma - p. 186 54. Epithelioid Hemangioendothelioma - p. 188 55. Epithelioid Sarcoma - p. 192 56. SMARCA4-Deficient Thoracic Sarcoma - p. 195 57. Extrarenal Malignant Rhabdoid Tumor - p. 195 58. Sclerosing Epithelioid Fibrosarcoma - p. 197 59. Epithelioid and Epithelial-Like Variants of Other Sarcomas - p. 199 60. Epithelioid Angiosarcoma - p. 199 61. Epithelioid Malignant Peripheral Nerve Sheath Tumor - p. 201 62. Epithelioid Gastrointestinal Stromal Tumor - p. 202 63. Epithelioid Myxofibrosarcoma - p. 202 64. Pleomorphic Liposarcoma, Epithelioid Variant - p. 202 65. Synovial Sarcoma, Epithelial/Glandular Variant - p. 203 66. Glandular Malignant Peripheral Nerve Sheath Tumor - p. 204 67. Other Epithelioid Variants of Specific Sarcomas - p. 204 68. References - p. 205 69. 7 Pleomorphic Sarcomas - p. 209 70. 8 Round Cell Tumors - p. 233 71. 9 Biphasic Tumors and Tumors With Mixed Patterns - p. 249 72. 10 Soft Tissue Tumors With Prominent Inflammatory Cells - p. 269 73. 11 Giant Cell–Rich Tumors - p. 297 74. 12 Adipocytic Tumors - p. 311 75. 13 Vascular Tumors - p. 341 76. Immunohistochemistry - p. 341 77. Classification of Vascular Tumors - p. 342 78. Vasoformative Pattern - p. 344 79. Epithelioid Lesions - p. 372 80. Spindle Cell Lesions - p. 379 81. References - p. 384 82. 14 Cartilaginous and Osseous Soft Tissue Lesions - p. 391 83. 15 Cutaneous Mesenchymal Tumors - p. 403 84. Spindle Cell Tumors - p. 405 85. Myxoid Tumors - p. 427 86. Epithelioid Tumors - p. 432 87. Pleomorphic Tumors - p. 449 88. Adipocytic Tumors - p. 452 89. References - p. 454 90. 16 Mesenchymal Tumors of the Gastrointestinal Tract - p. 459 91. 17 Lower Genital Soft Tissue Tumors - p. 499 92. 18 Applications of Molecular Testing to Differential Diagnosis - p. 513 93. Genetic Classification of Sarcomas - p. 513 94. Approaches to Molecular Diagnostics - p. 514 95. Molecular Features of Particular Entities - p. 524 96. Practical Applications of Molecular Diagnostic Testing - p. 545 97. Significance of Detecting an EWSR1 Gene Rearrangement by Fluorescence In Situ Hybridization - p. 549 98. Conclusions - p. 549 99. References - p. 551 100. Index - p. 557
Part of the in-depth and practical Pattern Recognition series, Practical Surgical Soft Tissue Pathology, 2nd Edition, helps you arrive at an accurate diagnosis by using a proven pattern-based approach. Leading diagnosticians guide you through the most common patterns seen in soft tissue pathology, applying appropriate immunohistochemistry and molecular testing, avoiding pitfalls, and making the best diagnosis. High-quality illustrations capture key morphologic patterns for a full range of common and rare tumor types, and a "visual index" at the beginning of the book directs you to the exact location of in-depth diagnostic guidance.
1. 1 Introduction - p. 1 2. 2 Biologic Potential, Grading, Staging, and Reporting of Sarcomas - p. 9 3. 3 Spindle Cell Tumors of Adults - p. 15 4. General Concepts - p. 16 5. Nonmesenchymal Neoplasms With Spindle Cell Cytomorphology - p. 18 6. Malignant Mesothelioma - p. 19 7. Nodular Fasciitis and Similar Pseudosarcomatous Myofibroblastic Lesions - p. 20 8. Myofibroma and Myopericytoma - p. 27 9. Phosphaturic Mesenchymal Tumor - p. 30 10. Myofibroblastoma and Variants - p. 31 11. Fibroma - p. 33 12. Calcifying Fibrous Tumor - p. 37 13. Angiofibroma of Soft Tissue - p. 37 14. Fibrous Histiocytoma and Variants - p. 39 15. Solitary Fibrous Tumor and Variants - p. 40 16. Fibromatoses - p. 46 17. Spindle Cell Lipoma - p. 50 18. Atypical Spindle Cell Lipomatous Tumor - p. 50 19. Schwannoma and Variants - p. 51 20. Neurofibroma - p. 57 21. Perineurioma - p. 61 22. Ganglioneuroma - p. 63 23. Benign Smooth Muscle Tumors - p. 64 24. Leiomyosarcoma - p. 66 25. Epstein-Barr Virus–Associated Smooth Muscle Neoplasm - p. 68 26. Lymphangiomyoma and Lymphangiomyomatosis - p. 68 27. Angiomatoid Fibrous Histiocytoma - p. 68 28. Synovial Sarcoma - p. 72 29. Malignant Peripheral Nerve Sheath Tumor - p. 76 30. Biphenotypic Sinonasal Sarcoma - p. 79 31. Sarcomas With Fibroblastic Differentiation - p. 81 32. Low-Grade Myofibroblastic Sarcoma - p. 84 33. Spindle Cell Rhabdomyosarcoma - p. 86 34. Clear Cell Sarcoma - p. 87 35. Pseudomyogenic Hemangioendothelioma - p. 89 36. Unclassified Spindle Cell Sarcomas - p. 92 37. References - p. 92 38. 4 Pediatric Spindle Cell Tumors - p. 101 39. 5 Tumors With Myxoid Stroma - p. 135 40. 6 Epithelioid and Epithelial-Like Tumors - p. 165 41. Approach to the Diagnosis of Epithelioid Tumors of Soft Tissue - p. 165 42. Epithelioid Hemangioma - p. 168 43. Glomus Tumor - p. 171 44. Myoepithelioma/Mixed Tumor/Myoepithelial Carcinoma of Soft Tissue - p. 173 45. PEComa of Soft Tissue - p. 177 46. Adult-Type Rhabdomyoma - p. 181 47. Epithelioid Schwannoma - p. 182 48. Granular Cell Tumor - p. 182 49. Sclerosing Perineurioma - p. 184 50. Extracranial Meningioma - p. 184 51. Ossifying Fibromyxoid Tumor - p. 185 52. Ependymoma of Soft Tissue - p. 185 53. Alveolar Soft Part Sarcoma - p. 186 54. Epithelioid Hemangioendothelioma - p. 188 55. Epithelioid Sarcoma - p. 192 56. SMARCA4-Deficient Thoracic Sarcoma - p. 195 57. Extrarenal Malignant Rhabdoid Tumor - p. 195 58. Sclerosing Epithelioid Fibrosarcoma - p. 197 59. Epithelioid and Epithelial-Like Variants of Other Sarcomas - p. 199 60. Epithelioid Angiosarcoma - p. 199 61. Epithelioid Malignant Peripheral Nerve Sheath Tumor - p. 201 62. Epithelioid Gastrointestinal Stromal Tumor - p. 202 63. Epithelioid Myxofibrosarcoma - p. 202 64. Pleomorphic Liposarcoma, Epithelioid Variant - p. 202 65. Synovial Sarcoma, Epithelial/Glandular Variant - p. 203 66. Glandular Malignant Peripheral Nerve Sheath Tumor - p. 204 67. Other Epithelioid Variants of Specific Sarcomas - p. 204 68. References - p. 205 69. 7 Pleomorphic Sarcomas - p. 209 70. 8 Round Cell Tumors - p. 233 71. 9 Biphasic Tumors and Tumors With Mixed Patterns - p. 249 72. 10 Soft Tissue Tumors With Prominent Inflammatory Cells - p. 269 73. 11 Giant Cell–Rich Tumors - p. 297 74. 12 Adipocytic Tumors - p. 311 75. 13 Vascular Tumors - p. 341 76. Immunohistochemistry - p. 341 77. Classification of Vascular Tumors - p. 342 78. Vasoformative Pattern - p. 344 79. Epithelioid Lesions - p. 372 80. Spindle Cell Lesions - p. 379 81. References - p. 384 82. 14 Cartilaginous and Osseous Soft Tissue Lesions - p. 391 83. 15 Cutaneous Mesenchymal Tumors - p. 403 84. Spindle Cell Tumors - p. 405 85. Myxoid Tumors - p. 427 86. Epithelioid Tumors - p. 432 87. Pleomorphic Tumors - p. 449 88. Adipocytic Tumors - p. 452 89. References - p. 454 90. 16 Mesenchymal Tumors of the Gastrointestinal Tract - p. 459 91. 17 Lower Genital Soft Tissue Tumors - p. 499 92. 18 Applications of Molecular Testing to Differential Diagnosis - p. 513 93. Genetic Classification of Sarcomas - p. 513 94. Approaches to Molecular Diagnostics - p. 514 95. Molecular Features of Particular Entities - p. 524 96. Practical Applications of Molecular Diagnostic Testing - p. 545 97. Significance of Detecting an EWSR1 Gene Rearrangement by Fluorescence In Situ Hybridization - p. 549 98. Conclusions - p. 549 99. References - p. 551 100. Index - p. 557
