In this issue of Clinics in Liver Disease, guest editor Dr. John V. Binu brings his considerable expertise to the topic of Primary Biliary Cholangitis. PBC leads to inflammation and scarring of the small bile ducts, and, if untreated, can lead to cirrhosis and liver failure. In this issue, top experts provide a state-of-the-art review of diagnosis and treatment for this chronic, progressive liver disorder.
Contains 13 practice-oriented topics including genetics of primary biliary cholangitis; prognostic scoring systems in PBC; overlap syndromes and PBC; non-invasive evaluation of fibrosis and portal hypertension in PBC; treatment of PBC: first- and second-line therapies; novel therapies for PBC; and more.
Provides in-depth clinical reviews on primary biliary cholangitis, offering actionable insights for clinical practice.
Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Contemporary Epidemiology of Primary Biliary Cholangitis - p. 555 9. Genetics of Primary Biliary Cholangitis - p. 571 10. Immunologic Responses and the Pathophysiology of Primary Biliary Cholangitis - p. 583 11. Autoantibodies in Primary Biliary Cholangitis - p. 613 12. Prognostic Scoring Systems in Primary Biliary Cholangitis: An Update - p. 629 13. Primary Biliary Cholangitis in Males: Pathogenesis, Clinical Presentation, and Prognosis - p. 643 14. The Inconvenient Truth of Primary Biliary Cholangitis/Autoimmune Hepatitis Overlap Syndrome - p. 657 15. Noninvasive Evaluation of Fibrosis and Portal Hypertension in Primary Biliary Cholangitis - p. 681 16. Hepatocellular Carcinoma in Primary Biliary Cholangitis - p. 691 17. Treatment of Primary Biliary Cholangitis: First-Line and Second-Line Therapies - p. 705 18. Evaluation and Management of Pruritus in Primary Biliary Cholangitis - p. 727 19. Novel Therapies in Primary Biliary Cholangitis: What Is in the Pipeline? - p. 747 20. Liver Transplantation for Primary Biliary Cholangitis - p. 765
In this issue of Clinics in Liver Disease, guest editor Dr. John V. Binu brings his considerable expertise to the topic of Primary Biliary Cholangitis. PBC leads to inflammation and scarring of the small bile ducts, and, if untreated, can lead to cirrhosis and liver failure. In this issue, top experts provide a state-of-the-art review of diagnosis and treatment for this chronic, progressive liver disorder.
Contains 13 practice-oriented topics including genetics of primary biliary cholangitis; prognostic scoring systems in PBC; overlap syndromes and PBC; non-invasive evaluation of fibrosis and portal hypertension in PBC; treatment of PBC: first- and second-line therapies; novel therapies for PBC; and more.
Provides in-depth clinical reviews on primary biliary cholangitis, offering actionable insights for clinical practice.
Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Contemporary Epidemiology of Primary Biliary Cholangitis - p. 555 9. Genetics of Primary Biliary Cholangitis - p. 571 10. Immunologic Responses and the Pathophysiology of Primary Biliary Cholangitis - p. 583 11. Autoantibodies in Primary Biliary Cholangitis - p. 613 12. Prognostic Scoring Systems in Primary Biliary Cholangitis: An Update - p. 629 13. Primary Biliary Cholangitis in Males: Pathogenesis, Clinical Presentation, and Prognosis - p. 643 14. The Inconvenient Truth of Primary Biliary Cholangitis/Autoimmune Hepatitis Overlap Syndrome - p. 657 15. Noninvasive Evaluation of Fibrosis and Portal Hypertension in Primary Biliary Cholangitis - p. 681 16. Hepatocellular Carcinoma in Primary Biliary Cholangitis - p. 691 17. Treatment of Primary Biliary Cholangitis: First-Line and Second-Line Therapies - p. 705 18. Evaluation and Management of Pruritus in Primary Biliary Cholangitis - p. 727 19. Novel Therapies in Primary Biliary Cholangitis: What Is in the Pipeline? - p. 747 20. Liver Transplantation for Primary Biliary Cholangitis - p. 765
