Protein Aggregation, book provides valuable insights into the factors driving protein aggregation, the impact on cellular function, and the role in various diseases, offering a comprehensive overview for researchers and professionals in the field of biomedicine and biochemistry.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Contributors - p. xi 6. Chapter One: Accurate coarse grained models for protein association and recognition - p. 1 7. Chapter Two: Deciphering protein aggregation: Insights into morphology, contributing factors, and molecular pathologies - p. 23 8. Chapter Three: Role of protein aggregates in bacteria - p. 73 9. Chapter Four: Investigation of new non-toxic inhibitors of fibril formation and preservatives for insulin preparations its analogues - p. 113 10. Chapter Five: Protein aggregation in health and disease: A looking glass of two faces - p. 145 11. Abstract - p. 146 12. 1 The way proteins fold - p. 146 13. 2 Protein aggregation - p. 153 14. 3 Phase separation and transition - p. 160 15. 4 In sickness: when aggregation turns bad - p. 164 16. 5 In health: functional amyloids and filaments - p. 176 17. 6 Dynamics: the dance that leads to fibrillation - p. 182 18. 7 Concluding remarks - p. 188 19. Acknowledgments - p. 189 20. References - p. 189 21. Chapter Six: Exploring therapeutic strategies based on chaperon-mediated disaggregation - p. 219 22. Chapter Seven: Tau PET probes for Alzheimer’s disease detection and their structural characterization - p. 255 23. Chapter Eight: Small molecule-mediated therapeutic approaches to target Tau and Alzheimer’s disease - p. 287
Protein Aggregation, book provides valuable insights into the factors driving protein aggregation, the impact on cellular function, and the role in various diseases, offering a comprehensive overview for researchers and professionals in the field of biomedicine and biochemistry.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Contributors - p. xi 6. Chapter One: Accurate coarse grained models for protein association and recognition - p. 1 7. Chapter Two: Deciphering protein aggregation: Insights into morphology, contributing factors, and molecular pathologies - p. 23 8. Chapter Three: Role of protein aggregates in bacteria - p. 73 9. Chapter Four: Investigation of new non-toxic inhibitors of fibril formation and preservatives for insulin preparations its analogues - p. 113 10. Chapter Five: Protein aggregation in health and disease: A looking glass of two faces - p. 145 11. Abstract - p. 146 12. 1 The way proteins fold - p. 146 13. 2 Protein aggregation - p. 153 14. 3 Phase separation and transition - p. 160 15. 4 In sickness: when aggregation turns bad - p. 164 16. 5 In health: functional amyloids and filaments - p. 176 17. 6 Dynamics: the dance that leads to fibrillation - p. 182 18. 7 Concluding remarks - p. 188 19. Acknowledgments - p. 189 20. References - p. 189 21. Chapter Six: Exploring therapeutic strategies based on chaperon-mediated disaggregation - p. 219 22. Chapter Seven: Tau PET probes for Alzheimer’s disease detection and their structural characterization - p. 255 23. Chapter Eight: Small molecule-mediated therapeutic approaches to target Tau and Alzheimer’s disease - p. 287
