Reciprocal Translation Between Pathophysiology and Practice in Health and Disease brings a novel perspective, closing the knowledge gap between normal/abnormal physiology. Chapters describe the basic mechanisms underlying a disease or trauma-related response, describe consequences in practice, and provide insights on how to use information to better understand disease outcomes. Other sections explore how these responses are beneficial and driven by similar hormones and inflammatory immune cell derived modulators. This is a must-have resource for those seeking an authoritative and comprehensive understanding on how to treat the basic mechanisms underlying disease or trauma-related responses.With contributions from Petronella L.M. Reijven.
1. Reciprocal Translation Between Pathophysiology and Practice in Health and Disease - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iv 5. Copyright - p. Page v 6. List of Illustrations - p. Page vi 7. List of Tables - p. Page vii 8. Chapter 1 : Reciprocal translation between pathophysiology and practice in health and disease - p. Page vii 9. Chapter 2 : General principles of the repair mechanism - p. Page 5 10. Chapter 3 : Cardiovascular responses to injury - p. Page 15 11. Chapter 4 : Insulin resistance as an adaptive mechanism - p. Page 26 12. Chapter 5 : Hypercholesterolemia, harm, or benefit? - p. Page 36 13. Chapter 6 : Macronutrient metabolism in starvation and stress - p. Page 46 14. Chapter 7 : The role of ectopic adipose tissue: Benefit or deleterious overflow? - p. Page 67 15. Chapter 8 : The gut/liver axis, inflammation, and the pathogenesis of metabolic syndrome - p. Page 87 16. Chapter 9 : Harm and benefit of the inflammatory response - p. Page 104 17. Chapter 10 : The beneficial role of inflammation and metabolic cycling (Warburg revisited) - p. Page 118 18. Chapter 11 : From hepatic encephalopathy to the quality of food protein and protein requirements: A serendipitous journey - p. Page 133 19. Chapter 12 : The underlying metabolism of hypoalbuminemia and its clinical effects - p. Page 148 20. Chapter 13 : Cardiovascular stress syndromes - p. Page 159 21. Chapter 14 : The benefit of moderate hyperglycemia and hyperlactatemia in critical illness or synthesis of biomass - p. Page 175 22. Chapter 15 : Anemia as an adaptive phenomenon - p. Page 190 23. Chapter 16 : Vitamin D in health and disease - p. Page 199 24. Chapter 17 : Decreases of plasma solutes in health and disease: Deficiency or resulting from changing binding proteins and distribution volume? - p. Page 215 25. Chapter 18 : Comparable metabolism in pregnancy and cancer: A universal role of the Warburg effect - p. Page 229 26. Chapter 19 : Nutritional assessment and the role of preexisting inflammation with a bearing on COVID-19 - p. Page 240 27. Chapter 20 : The harm afflicted by NSAIDs, statins, and oral antidiabetics by blocking adaptive inflammatory metabolism - p. Page 254 28. Chapter 21 : Benefit and concern of ketogenic and vegan diets: A revisit to pathophysiology - p. Page 265 29. Chapter 22 : Pathophysiology in practice: How to manage gastrointestinal surgery in acute and elective disease conditions - p. Page 276 30. Chapter 23 : The pathophysiology underlying the obesity and plasma cholesterol paradoxes - p. Page 299 31. Chapter 24 : The final conclusion: Dogma, bias, and big data - p. Page 308 32. Index - p. Page 320
Reciprocal Translation Between Pathophysiology and Practice in Health and Disease brings a novel perspective, closing the knowledge gap between normal/abnormal physiology. Chapters describe the basic mechanisms underlying a disease or trauma-related response, describe consequences in practice, and provide insights on how to use information to better understand disease outcomes. Other sections explore how these responses are beneficial and driven by similar hormones and inflammatory immune cell derived modulators. This is a must-have resource for those seeking an authoritative and comprehensive understanding on how to treat the basic mechanisms underlying disease or trauma-related responses.With contributions from Petronella L.M. Reijven.
1. Reciprocal Translation Between Pathophysiology and Practice in Health and Disease - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iv 5. Copyright - p. Page v 6. List of Illustrations - p. Page vi 7. List of Tables - p. Page vii 8. Chapter 1 : Reciprocal translation between pathophysiology and practice in health and disease - p. Page vii 9. Chapter 2 : General principles of the repair mechanism - p. Page 5 10. Chapter 3 : Cardiovascular responses to injury - p. Page 15 11. Chapter 4 : Insulin resistance as an adaptive mechanism - p. Page 26 12. Chapter 5 : Hypercholesterolemia, harm, or benefit? - p. Page 36 13. Chapter 6 : Macronutrient metabolism in starvation and stress - p. Page 46 14. Chapter 7 : The role of ectopic adipose tissue: Benefit or deleterious overflow? - p. Page 67 15. Chapter 8 : The gut/liver axis, inflammation, and the pathogenesis of metabolic syndrome - p. Page 87 16. Chapter 9 : Harm and benefit of the inflammatory response - p. Page 104 17. Chapter 10 : The beneficial role of inflammation and metabolic cycling (Warburg revisited) - p. Page 118 18. Chapter 11 : From hepatic encephalopathy to the quality of food protein and protein requirements: A serendipitous journey - p. Page 133 19. Chapter 12 : The underlying metabolism of hypoalbuminemia and its clinical effects - p. Page 148 20. Chapter 13 : Cardiovascular stress syndromes - p. Page 159 21. Chapter 14 : The benefit of moderate hyperglycemia and hyperlactatemia in critical illness or synthesis of biomass - p. Page 175 22. Chapter 15 : Anemia as an adaptive phenomenon - p. Page 190 23. Chapter 16 : Vitamin D in health and disease - p. Page 199 24. Chapter 17 : Decreases of plasma solutes in health and disease: Deficiency or resulting from changing binding proteins and distribution volume? - p. Page 215 25. Chapter 18 : Comparable metabolism in pregnancy and cancer: A universal role of the Warburg effect - p. Page 229 26. Chapter 19 : Nutritional assessment and the role of preexisting inflammation with a bearing on COVID-19 - p. Page 240 27. Chapter 20 : The harm afflicted by NSAIDs, statins, and oral antidiabetics by blocking adaptive inflammatory metabolism - p. Page 254 28. Chapter 21 : Benefit and concern of ketogenic and vegan diets: A revisit to pathophysiology - p. Page 265 29. Chapter 22 : Pathophysiology in practice: How to manage gastrointestinal surgery in acute and elective disease conditions - p. Page 276 30. Chapter 23 : The pathophysiology underlying the obesity and plasma cholesterol paradoxes - p. Page 299 31. Chapter 24 : The final conclusion: Dogma, bias, and big data - p. Page 308 32. Index - p. Page 320
