Risk Factors for Psychosis: Paradigms, Mechanisms, and Prevention combines the related, but disparate research endeavors into a single text that considers all risk factors for psychosis, including biological, psychological and environmental factors. The book also introduces the ethics and current treatment evidence that attempts to ameliorate risk or reduce the number of individuals with risk factors developing a psychotic disorder. Finally, the book highlights new research paradigms that will further enhance the field in the future.
Psychotic disorders affect more than 50 million people worldwide, creating a devastating effect on lives and causing major financial and emotional impact on families and on society as a whole. The search for risk factors for psychosis has developed rapidly over the past decades, invigorated by changes in the thinking about the malleability and treatability of psychotic disorders. The paradigms for investigating psychosis risk have developed, often in parallel, but there has been no book to date that has summarized and synthesized the current approaches.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Contributors - p. ix 6. Foreword - p. xiii 7. Chapter 1. Historical perspectives on psychosis risk - p. 1 8. Chapter 2. Principles of risk, screening, and prevention in psychiatry - p. 11 9. I. Risk paradigms - p. 43 10. Chapter 3. At-risk mental states - p. 47 11. Chapter 4. Subjective disturbances in emerging psychosis: basic symptoms and self-disturbances - p. 59 12. Chapter 5. Schizotypy, schizotypal personality, and psychosis risk - p. 81 13. Chapter 6. Familial high risk and high-risk studies - p. 101 14. Chapter 7. Psychotic-like experiences in the general population - p. 119 15. Chapter 8. 22q11.2 deletion syndrome: a neurodevelopmental model of psychosis - p. 143 16. II. Specific areas and risk - p. 164 17. Chapter 9. Neuroimaging studies in people at clinical high risk for psychosis - p. 167 18. Chapter 10. Genetic studies of psychosis - p. 183 19. Chapter 11. Immune processes and risk of psychosis - p. 211 20. Chapter 12. Neurochemical models of psychosis risk and onset - p. 229 21. Chapter 13. Clinical risk factors for psychosis - p. 249 22. Chapter 14. Cognitive risk factors for psychosis - p. 269 23. Chapter 15. Society and risk of psychosis - p. 289 24. Chapter 16. Is there sufficient evidence that cannabis use is a risk factor for psychosis? - p. 305 25. III. Interventions - p. 331 26. Chapter 17. The ethics of identifying and treating psychosis risk - p. 335 27. Chapter 18. Indicated prevention in psychosis risk—psychological approaches - p. 351 28. Chapter 19. Pharmacological intervention for people at risk of psychotic disorder - p. 371 29. Chapter 20. International services for assessing and treating psychosis risk - p. 383 30. Chapter 21. New paradigms to study psychosis risk: clinical staging, pluripotency, and dynamic prediction - p. 399 31. Chapter 22. Future directions in risk research - p. 417 32. Index - p. 431
Risk Factors for Psychosis: Paradigms, Mechanisms, and Prevention combines the related, but disparate research endeavors into a single text that considers all risk factors for psychosis, including biological, psychological and environmental factors. The book also introduces the ethics and current treatment evidence that attempts to ameliorate risk or reduce the number of individuals with risk factors developing a psychotic disorder. Finally, the book highlights new research paradigms that will further enhance the field in the future.
Psychotic disorders affect more than 50 million people worldwide, creating a devastating effect on lives and causing major financial and emotional impact on families and on society as a whole. The search for risk factors for psychosis has developed rapidly over the past decades, invigorated by changes in the thinking about the malleability and treatability of psychotic disorders. The paradigms for investigating psychosis risk have developed, often in parallel, but there has been no book to date that has summarized and synthesized the current approaches.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Contributors - p. ix 6. Foreword - p. xiii 7. Chapter 1. Historical perspectives on psychosis risk - p. 1 8. Chapter 2. Principles of risk, screening, and prevention in psychiatry - p. 11 9. I. Risk paradigms - p. 43 10. Chapter 3. At-risk mental states - p. 47 11. Chapter 4. Subjective disturbances in emerging psychosis: basic symptoms and self-disturbances - p. 59 12. Chapter 5. Schizotypy, schizotypal personality, and psychosis risk - p. 81 13. Chapter 6. Familial high risk and high-risk studies - p. 101 14. Chapter 7. Psychotic-like experiences in the general population - p. 119 15. Chapter 8. 22q11.2 deletion syndrome: a neurodevelopmental model of psychosis - p. 143 16. II. Specific areas and risk - p. 164 17. Chapter 9. Neuroimaging studies in people at clinical high risk for psychosis - p. 167 18. Chapter 10. Genetic studies of psychosis - p. 183 19. Chapter 11. Immune processes and risk of psychosis - p. 211 20. Chapter 12. Neurochemical models of psychosis risk and onset - p. 229 21. Chapter 13. Clinical risk factors for psychosis - p. 249 22. Chapter 14. Cognitive risk factors for psychosis - p. 269 23. Chapter 15. Society and risk of psychosis - p. 289 24. Chapter 16. Is there sufficient evidence that cannabis use is a risk factor for psychosis? - p. 305 25. III. Interventions - p. 331 26. Chapter 17. The ethics of identifying and treating psychosis risk - p. 335 27. Chapter 18. Indicated prevention in psychosis risk—psychological approaches - p. 351 28. Chapter 19. Pharmacological intervention for people at risk of psychotic disorder - p. 371 29. Chapter 20. International services for assessing and treating psychosis risk - p. 383 30. Chapter 21. New paradigms to study psychosis risk: clinical staging, pluripotency, and dynamic prediction - p. 399 31. Chapter 22. Future directions in risk research - p. 417 32. Index - p. 431
