RNA Modification, Volume 41 examines the powerful ability to regulate the function of RNA molecules or modify the message transmitted by RNA molecules. Chapters in this newly released volume include The Importance of Being Modified: Modifications Shape RNA Function through Chemistry, Structure and Dynamics, The evolution of multi-substrate specificity by RNA modification enzymes, TrmD: a methyl transferase for tRNA methylation with m1G37, Structures and activities of the Elongator complex and its co-factors, RNA pseudouridylation: Mechanism and Function, The activity of 5’3' exonucleases on hypo modified tRNA substrates and other structured RNAs, and the Synthesis, heterogeneity and function of post-transcriptional nucleotide modifications in eukaryotic ribosomal RNAs.
This field has recently seen a very rapid progress in the understanding of the mechanism and enzymes involved in RNA modification. This volume presents some of the most recent advances in the identification and function of enzymes involved in modifying RNA molecules.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. ix 6. Preface - p. xi 7. Chapter One: The Importance of Being Modified: The Role of RNA Modifications in Translational Fidelity - p. xi 8. Chapter Two: The Evolution of Substrate Specificity by tRNA Modification Enzymes - p. 50 9. Chapter Three: TrmD: A Methyl Transferase for tRNA Methylation With m1G37 - p. 88 10. Chapter Four: Structures and Activities of the Elongator Complex and Its Cofactors - p. 115 11. Chapter Five: Posttranscriptional RNA Pseudouridylation - p. 149 12. Chapter Six: Synthesis, Function, and Heterogeneity of snoRNA-Guided Posttranscriptional Nucleoside Modifications in Eukaryotic Ribosomal RNAs - p. 167 13. Chapter Seven: Adenosine Deaminases That Act on RNA (ADARs) - p. 213 14. Chapter Eight: Reading the Epitranscriptome: New Techniques and Perspectives - p. 268 15. Chapter Nine: Impact of RNA Modifications and RNA-Modifying Enzymes on Eukaryotic Ribonucleases - p. 298
RNA Modification, Volume 41 examines the powerful ability to regulate the function of RNA molecules or modify the message transmitted by RNA molecules. Chapters in this newly released volume include The Importance of Being Modified: Modifications Shape RNA Function through Chemistry, Structure and Dynamics, The evolution of multi-substrate specificity by RNA modification enzymes, TrmD: a methyl transferase for tRNA methylation with m1G37, Structures and activities of the Elongator complex and its co-factors, RNA pseudouridylation: Mechanism and Function, The activity of 5’3' exonucleases on hypo modified tRNA substrates and other structured RNAs, and the Synthesis, heterogeneity and function of post-transcriptional nucleotide modifications in eukaryotic ribosomal RNAs.
This field has recently seen a very rapid progress in the understanding of the mechanism and enzymes involved in RNA modification. This volume presents some of the most recent advances in the identification and function of enzymes involved in modifying RNA molecules.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. ix 6. Preface - p. xi 7. Chapter One: The Importance of Being Modified: The Role of RNA Modifications in Translational Fidelity - p. xi 8. Chapter Two: The Evolution of Substrate Specificity by tRNA Modification Enzymes - p. 50 9. Chapter Three: TrmD: A Methyl Transferase for tRNA Methylation With m1G37 - p. 88 10. Chapter Four: Structures and Activities of the Elongator Complex and Its Cofactors - p. 115 11. Chapter Five: Posttranscriptional RNA Pseudouridylation - p. 149 12. Chapter Six: Synthesis, Function, and Heterogeneity of snoRNA-Guided Posttranscriptional Nucleoside Modifications in Eukaryotic Ribosomal RNAs - p. 167 13. Chapter Seven: Adenosine Deaminases That Act on RNA (ADARs) - p. 213 14. Chapter Eight: Reading the Epitranscriptome: New Techniques and Perspectives - p. 268 15. Chapter Nine: Impact of RNA Modifications and RNA-Modifying Enzymes on Eukaryotic Ribonucleases - p. 298
