For over 60 years, residents and practicing pathologists have turned to Rosai and Ackerman's Surgical Pathology for definitive guidance on every aspect of the field, delivered in a readable, easy-to-digest, and engaging manner. In the two-volume 11th Edition, a dynamic new author team ensures that this classic text retains its signature anecdotal style, while revising the content to bring you fully up to date. Widely used for board exam preparation, as well as for everyday reference in practice, this leading resource equips you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities.
1. 1 Introduction - p. 1 2. Section 1 Dermatopathology - p. 3 3. 2 Dermatoses - p. 6 4. Abstract - p. 6 5. Introduction to Dermatopathology - p. 7 6. Normal Anatomy - p. 6.e1 7. Inflammatory Dermatoses - p. 8 8. Inflammatory Dermatoses With Epidermal Change - p. 8 9. Inflammatory Dermatoses With Dermal but Not Epidermal Change - p. 15 10. Sclerosing Disorders - p. 22 11. Panniculitis - p. 23 12. Vesiculobullous Diseases - p. 25 13. Infections - p. 29 14. Miscellaneous Disorders - p. 35 15. References - p. 37 16. 3 Tumors and Tumorlike Conditions of the Skin - p. 45 17. Abstract - p. 45 18. Epidermis - p. 45.e1 19. Squamous Cell Carcinoma - p. 48 20. Pseudoepitheliomatous Hyperplasia - p. 50 21. Basal Cell Carcinoma - p. 50 22. Skin Adnexa - p. 54 23. Melanocytes - p. 67 24. Neuroendocrine Cells - p. 87 25. Dermis - p. 90 26. Vascular Tumors and Tumorlike Conditions - p. 98 27. Lymphoid Tumors and Tumorlike Conditions - p. 105 28. Other Primary Tumors and Tumorlike Conditions - p. 111 29. Metastatic Tumors - p. 111 30. References - p. 113 31. Section 2 Head and Neck Pathology - p. 143 32. 4 Upper Aerodigestive Tract - p. 146 33. Abstract - p. 146 34. Oral Cavity and Oropharynx - p. 147 35. Respiratory Tract - p. 164 36. Larynx - p. 183 37. Trachea - p. 196 38. References - p. 197 39. 5 Mandible and Maxilla - p. 212 40. 6 Major and Minor Salivary Glands - p. 235 41. Abstract - p. 235 42. Normal Anatomy - p. 236 43. Heterotopia - p. 235.e1 44. Sialolithiasis - p. 235.e1 45. Sialadenitis - p. 235.e1 46. Benign Lymphoepithelial Cysts and HIV-Related Lesions - p. 237 47. Lymphoepithelial Sialadenitis (Mikulicz Disease) and Sjögren Syndrome - p. 238 48. Irradiation Effect - p. 239 49. Other Non-Neoplastic Lesions - p. 239 50. Epithelial Tumors - p. 240 51. Malignant Lymphoma - p. 256 52. Other Primary Tumors - p. 256 53. Metastatic Tumors - p. 257 54. General Features of Salivary Gland Tumors - p. 257 55. References - p. 259 56. 7 Ear - p. 269 57. 8 Thyroid Gland - p. 278 58. Abstract - p. 278 59. Normal Anatomy and Thyroid Gland Development - p. 279 60. Congenital Abnormalities - p. 280 61. Thyroiditis - p. 282 62. Hyperplasia - p. 287 63. Tumors - p. 293 64. References - p. 335 65. 9 Parathyroid Glands - p. 355 66. Section 3 Thoracic Pathology - p. 369 67. 10 Lung - p. 372 68. Abstract - p. 372 69. Normal Anatomy - p. 373 70. Non-Neoplastic Lesions - p. 372.e1 71. Carcinoma - p. 399 72. Other Primary Tumors - p. 418 73. Metastatic Tumors - p. 429 74. References - p. 431 75. 11 Pleura - p. 444 76. 12 Mediastinum - p. 457 77. Abstract - p. 457 78. Generalities - p. 458 79. Inflammatory Diseases - p. 458 80. Cysts (Other Than Thymic) - p. 459 81. Thymus - p. 460 82. Malignant Lymphoma - p. 484 83. Neurogenic Tumors - p. 489 84. Tumors of Paraganglia - p. 490 85. Mesenchymal Tumors - p. 491 86. Metastatic Tumors - p. 492 87. References - p. 492 88. Section 4 Gastrointestinal and Hepatobiliary Tract - p. 500 89. 13 Esophagus - p. 502 90. 14 Stomach - p. 528 91. Abstract - p. 528 92. Normal Anatomy - p. 529 93. Heterotopic Tissues - p. 528.e1 94. Hypertrophic Pyloric Stenosis - p. 530 95. Chronic Gastritis - p. 530 96. Other Types of Gastritis - p. 532 97. Peptic and Other Benign Ulcers - p. 533 98. Other Non-Neoplastic Lesions - p. 535 99. Polyps - p. 536 100. Ménétrier Disease and Zollinger–Ellison Syndrome - p. 539 101. Regenerative Changes and Dysplasia - p. 539 102. Carcinoma - p. 541 103. Well-Differentiated Neuroendocrine Tumors (“Carcinoid Tumors”) - p. 548 104. Stromal Tumors (Gastrointestinal Stromal Tumors and Related Lesions) - p. 550 105. Lymphoid Tumors and Tumorlike Conditions - p. 553 106. Other Tumors - p. 557 107. References - p. 559 108. 15 Small Bowel - p. 568 109. Abstract - p. 568 110. Normal Anatomy - p. 569 111. Congenital Defects - p. 570 112. Inflammatory Disorders - p. 572 113. Polyps and Tumors - p. 590 114. References - p. 605 115. 16 Appendix - p. 617 116. 17 Large Bowel - p. 648 117. Abstract - p. 648 118. Normal Anatomy of the Large Bowel - p. 649 119. Hirschsprung Disease and Related Disorders - p. 648.e1 120. Diverticulosis - p. 651 121. Colitis - p. 652 122. Other Non-Neoplastic Lesions - p. 663 123. Tumors - p. 668 124. References - p. 689 125. 18 Anus - p. 703 126. 19 Liver - p. 726 127. Abstract - p. 726 128. Normal Anatomy - p. 727 129. Biopsy - p. 726.e1 130. Viral Hepatitis - p. 728 131. Drug-Induced and Toxic Liver Injury - p. 739 132. Steatosis and Steatohepatitis - p. 744 133. Cholestasis, Biliary Diseases, and Autoimmune Hepatitis - p. 750 134. Cirrhosis - p. 761 135. Childhood Disorders and Disorders of Metabolism - p. 762 136. Disorders of Copper and Iron Metabolism - p. 769 137. Fibropolycystic Diseases (Ductal Plate Malformation) - p. 772 138. Vascular Disorders - p. 775 139. Liver Disease in Pregnancy - p. 777 140. Liver Involvement in Systemic Diseases - p. 777 141. Liver Pathology in Organ Transplantation - p. 781 142. References - p. 785 143. 20 Liver - p. 803 144. Abstract - p. 803 145. Hepatic Tumors and Tumorlike Conditions - p. 804 146. Bile Duct Tumors and Tumorlike Conditions - p. 819 147. Mesenchymal Tumors and Tumorlike Conditions - p. 824 148. Malignant Lymphoma and Related Lesions - p. 829 149. Other Primary Tumors and Tumorlike Conditions - p. 831 150. Metastatic Tumors - p. 831 151. References - p. 833 152. 21 Gallbladder and Extrahepatic Bile Ducts - p. 844 153. 22 Pancreas and Ampullary Region - p. 886 154. Abstract - p. 886 155. Pancreas - p. 887 156. Ampullary Region - p. 921 157. References - p. 923 158. Section 5 Genitourinary Pathology - p. 933 159. 23 Kidney - p. 936 160. Abstract - p. 936 161. Renal Biopsy - p. 936.e1 162. Normal Structure of the Glomerulus - p. 938 163. Classification of Glomerular Disease - p. 940 164. Glomerular Lesions Associated With the Nephrotic Syndrome - p. 940 165. Glomerular Lesions Associated With the Syndrome of Acute Nephritis - p. 958 166. Glomerular Lesions Associated With Vascular Diseases - p. 973 167. Renal Diseases of Pregnancy - p. 979 168. Hereditary Glomerular Diseases - p. 980 169. Renal Transplant Pathology - p. 984 170. Tubulointerstitial Diseases - p. 989 171. Renal Vascular Disease - p. 995 172. Radiation Nephropathy - p. 998 173. Cystic Diseases of the Kidney - p. 998 174. References - p. 1002 175. 24 Kidney - p. 1014 176. Abstract - p. 1014 177. Pediatric Tumors and Tumorlike Conditions - p. 1015 178. Adult Tumors and Tumorlike Conditions - p. 1025 179. References - p. 1049 180. 25 Bladder - p. 1066 181. 26 Prostate and Seminal Vesicles - p. 1097 182. Abstract - p. 1097 183. Prostate - p. 1098 184. Prostatic Urethra - p. 1121 185. Seminal Vesicles and Cowper's Glands - p. 1121 186. References - p. 1122 187. 27 Testis and Testicular Adnexa - p. 1135 188. Abstract - p. 1135 189. Testis - p. 1136 190. Testicular Adnexa - p. 1157 191. References - p. 1164 192. 28 Penis and Scrotum - p. 1175 193. 29 Adrenal Gland and Other Paraganglia - p. 1190 194. Section 6 Female Reproductive System - p. 1221 195. 30 Vulva - p. 1224 196. 31 Vagina - p. 1248 197. 32 Uterus - p. 1260 198. Abstract - p. 1260 199. Normal Anatomy - p. 1261 200. Remnants and Ectopias - p. 1261 201. Squamous and Other Metaplasias - p. 1260.e1 202. Inflammatory Lesions - p. 1263 203. Non-Neoplastic Glandular Lesions - p. 1263 204. Non-Neoplastic Stromal Lesions (Including Endometriosis and Related Processes) - p. 1265 205. Human Papilloma Virus and the Lower Female Genital Tract - p. 1266 206. Tumors - p. 1267 207. References - p. 1284 208. 33 Uterus - p. 1294 209. Abstract - p. 1294 210. Normal Anatomy - p. 1295 211. Effects of Hormone Administration - p. 1296 212. Endometritis - p. 1297 213. Metaplasia - p. 1298 214. Adenomyosis and Endometriosis - p. 1300 215. Dysfunctional Uterine Bleeding - p. 1302 216. Endometrial Hyperplasia Without Atypia, Atypical Hyperplasia, and Variants - p. 1303 217. Curettage and Biopsy - p. 1305 218. Tumors - p. 1306 219. References - p. 1340 220. 34 Fallopian Tube - p. 1356 221. 35 Ovary - p. 1367 222. Abstract - p. 1367 223. Normal Anatomy - p. 1368 224. Gonadal Dysgenesis - p. 1367.e1 225. Cysts, Stromal Hyperplasia, and Other Non-Neoplastic Lesions - p. 1369 226. Inflammation - p. 1373 227. Endometriosis - p. 1374 228. Tumors - p. 1374 229. References - p. 1417 230. Section 7 Breast - p. 1431 231. 36 Breast - p. 1434 232. Abstract - p. 1434 233. Normal Anatomy - p. 1435 234. Ectopia - p. 1436 235. Inflammatory and Related Lesions - p. 1437 236. Benign Breast Disease - p. 1440 237. Intraductal Proliferative Lesions and Nonproliferative Changes - p. 1440 238. Fibroepithelial Lesions - p. 1447 239. Adenosis and Sclerosing Lesions - p. 1451 240. Papillary Lesions - p. 1456 241. Nipple Lesions - p. 1462 242. Carcinoma - p. 1464 243. Salivary Gland and Skin Adnexal-Type Tumors (Including Myoepithelial Tumors) - p. 1503 244. Stromal and Vascular Tumors and Tumorlike Conditions - p. 1504 245. Lymphoid Tumors and Tumorlike Conditions - p. 1506 246. Other Primary Tumors and Tumorlike Conditions - p. 1507 247. Metastatic Tumors - p. 1509 248. Breast Diseases in Children and Adolescents - p. 1510 249. Breast Diseases in Males - p. 1511 250. References - p. 1512 251. Section 8 Hematopathology - p. 1527 252. 37 Lymph Nodes - p. 1530 253. Abstract - p. 1530 254. Normal Anatomy - p. 1531 255. Lymph Node Evaluation - p. 1530.e1 256. Primary Immunodeficiencies - p. 1538 257. Patterns of Hyperplasia - p. 1539 258. Inflammatory/Hyperplastic Diseases - p. 1543 259. Malignant Lymphoma - p. 1561 260. Tumors of the Accessory Immune System - p. 1594 261. Vascular Tumors and Tumorlike Conditions - p. 1597 262. Other Primary Tumors and Tumorlike Conditions - p. 1598 263. Lymph Node Inclusions - p. 1601 264. Other Non-Neoplastic Lesions - p. 1604 265. Metastatic Tumors - p. 1605 266. References - p. 1610 267. 38 Spleen - p. 1632 268. 39 Bone Marrow - p. 1658 269. Abstract - p. 1658 270. Biopsy Procedure and Processing of Specimen - p. 1659 271. Immunohistochemistry - p. 1660 272. Normocellular Bone Marrow - p. 1662 273. Alterations in Cellularity - p. 1663 274. Osteopetrosis - p. 1665 275. Bone Marrow Necrosis - p. 1665 276. Inflammatory Disorders - p. 1666 277. Human Immunodeficiency Virus Syndrome (HIV, AIDS) - p. 1669 278. Leukemias and Related Disorders - p. 1670 279. Systemic Mastocytosis - p. 1684 280. Mature B-Cell Neoplasms - p. 1687 281. Non-Hodgkin Lymphoma - p. 1693 282. Benign Lymphocytic Aggregates - p. 1703 283. Hodgkin Lymphoma - p. 1704 284. Histiocytic Disorders - p. 1706 285. Plasma Cell Dyscrasias - p. 1709 286. Systemic Polyclonal B-Immunoblastic Proliferation - p. 1716 287. Metastatic Tumors - p. 1717 288. Lipid Storage Diseases - p. 1719 289. Hematopoietic Cell Transplantation - p. 1721 290. Acknowledgment - p. 1724 291. References - p. 1724 292. Section 9 Bone and Soft Tissue Pathology - p. 1737 293. 40 Bone and Joints - p. 1740 294. Abstract - p. 1740 295. Bone - p. 1741 296. Joints and Related Structures - p. 1789 297. References - p. 1797 298. 41 Soft Tissues - p. 1810 299. Abstract - p. 1810 300. Normal Anatomy - p. 1811 301. Infections and Hematomas - p. 1810.e1 302. Tumors - p. 1810.e1 303. References - p. 1892 304. Section 10 Cardiovascular Pathology - p. 1914 305. 42 Cardiovascular System - p. 1916 306. Section 11 Central Nervous System - p. 1945 307. 43 Central Nervous System - p. 1948 308. Abstract - p. 1948 309. Normal Anatomy - p. 1949 310. Developmental Abnormalities - p. 1948.e1 311. Cerebrovascular Disorders - p. 1955 312. Inflammatory Diseases - p. 1962 313. Infectious Diseases - p. 1967 314. Primary Tumors - p. 1977 315. Secondary/Metastatic Tumors - p. 2059 316. Acknowledgments - p. 2061 317. References - p. 2061 318. 44 Pituitary Gland - p. 2086 319. 45 Eye and Ocular Adnexa - p. 2112 320. Index - p. I-1
For over 60 years, residents and practicing pathologists have turned to Rosai and Ackerman's Surgical Pathology for definitive guidance on every aspect of the field, delivered in a readable, easy-to-digest, and engaging manner. In the two-volume 11th Edition, a dynamic new author team ensures that this classic text retains its signature anecdotal style, while revising the content to bring you fully up to date. Widely used for board exam preparation, as well as for everyday reference in practice, this leading resource equips you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities.
1. 1 Introduction - p. 1 2. Section 1 Dermatopathology - p. 3 3. 2 Dermatoses - p. 6 4. Abstract - p. 6 5. Introduction to Dermatopathology - p. 7 6. Normal Anatomy - p. 6.e1 7. Inflammatory Dermatoses - p. 8 8. Inflammatory Dermatoses With Epidermal Change - p. 8 9. Inflammatory Dermatoses With Dermal but Not Epidermal Change - p. 15 10. Sclerosing Disorders - p. 22 11. Panniculitis - p. 23 12. Vesiculobullous Diseases - p. 25 13. Infections - p. 29 14. Miscellaneous Disorders - p. 35 15. References - p. 37 16. 3 Tumors and Tumorlike Conditions of the Skin - p. 45 17. Abstract - p. 45 18. Epidermis - p. 45.e1 19. Squamous Cell Carcinoma - p. 48 20. Pseudoepitheliomatous Hyperplasia - p. 50 21. Basal Cell Carcinoma - p. 50 22. Skin Adnexa - p. 54 23. Melanocytes - p. 67 24. Neuroendocrine Cells - p. 87 25. Dermis - p. 90 26. Vascular Tumors and Tumorlike Conditions - p. 98 27. Lymphoid Tumors and Tumorlike Conditions - p. 105 28. Other Primary Tumors and Tumorlike Conditions - p. 111 29. Metastatic Tumors - p. 111 30. References - p. 113 31. Section 2 Head and Neck Pathology - p. 143 32. 4 Upper Aerodigestive Tract - p. 146 33. Abstract - p. 146 34. Oral Cavity and Oropharynx - p. 147 35. Respiratory Tract - p. 164 36. Larynx - p. 183 37. Trachea - p. 196 38. References - p. 197 39. 5 Mandible and Maxilla - p. 212 40. 6 Major and Minor Salivary Glands - p. 235 41. Abstract - p. 235 42. Normal Anatomy - p. 236 43. Heterotopia - p. 235.e1 44. Sialolithiasis - p. 235.e1 45. Sialadenitis - p. 235.e1 46. Benign Lymphoepithelial Cysts and HIV-Related Lesions - p. 237 47. Lymphoepithelial Sialadenitis (Mikulicz Disease) and Sjögren Syndrome - p. 238 48. Irradiation Effect - p. 239 49. Other Non-Neoplastic Lesions - p. 239 50. Epithelial Tumors - p. 240 51. Malignant Lymphoma - p. 256 52. Other Primary Tumors - p. 256 53. Metastatic Tumors - p. 257 54. General Features of Salivary Gland Tumors - p. 257 55. References - p. 259 56. 7 Ear - p. 269 57. 8 Thyroid Gland - p. 278 58. Abstract - p. 278 59. Normal Anatomy and Thyroid Gland Development - p. 279 60. Congenital Abnormalities - p. 280 61. Thyroiditis - p. 282 62. Hyperplasia - p. 287 63. Tumors - p. 293 64. References - p. 335 65. 9 Parathyroid Glands - p. 355 66. Section 3 Thoracic Pathology - p. 369 67. 10 Lung - p. 372 68. Abstract - p. 372 69. Normal Anatomy - p. 373 70. Non-Neoplastic Lesions - p. 372.e1 71. Carcinoma - p. 399 72. Other Primary Tumors - p. 418 73. Metastatic Tumors - p. 429 74. References - p. 431 75. 11 Pleura - p. 444 76. 12 Mediastinum - p. 457 77. Abstract - p. 457 78. Generalities - p. 458 79. Inflammatory Diseases - p. 458 80. Cysts (Other Than Thymic) - p. 459 81. Thymus - p. 460 82. Malignant Lymphoma - p. 484 83. Neurogenic Tumors - p. 489 84. Tumors of Paraganglia - p. 490 85. Mesenchymal Tumors - p. 491 86. Metastatic Tumors - p. 492 87. References - p. 492 88. Section 4 Gastrointestinal and Hepatobiliary Tract - p. 500 89. 13 Esophagus - p. 502 90. 14 Stomach - p. 528 91. Abstract - p. 528 92. Normal Anatomy - p. 529 93. Heterotopic Tissues - p. 528.e1 94. Hypertrophic Pyloric Stenosis - p. 530 95. Chronic Gastritis - p. 530 96. Other Types of Gastritis - p. 532 97. Peptic and Other Benign Ulcers - p. 533 98. Other Non-Neoplastic Lesions - p. 535 99. Polyps - p. 536 100. Ménétrier Disease and Zollinger–Ellison Syndrome - p. 539 101. Regenerative Changes and Dysplasia - p. 539 102. Carcinoma - p. 541 103. Well-Differentiated Neuroendocrine Tumors (“Carcinoid Tumors”) - p. 548 104. Stromal Tumors (Gastrointestinal Stromal Tumors and Related Lesions) - p. 550 105. Lymphoid Tumors and Tumorlike Conditions - p. 553 106. Other Tumors - p. 557 107. References - p. 559 108. 15 Small Bowel - p. 568 109. Abstract - p. 568 110. Normal Anatomy - p. 569 111. Congenital Defects - p. 570 112. Inflammatory Disorders - p. 572 113. Polyps and Tumors - p. 590 114. References - p. 605 115. 16 Appendix - p. 617 116. 17 Large Bowel - p. 648 117. Abstract - p. 648 118. Normal Anatomy of the Large Bowel - p. 649 119. Hirschsprung Disease and Related Disorders - p. 648.e1 120. Diverticulosis - p. 651 121. Colitis - p. 652 122. Other Non-Neoplastic Lesions - p. 663 123. Tumors - p. 668 124. References - p. 689 125. 18 Anus - p. 703 126. 19 Liver - p. 726 127. Abstract - p. 726 128. Normal Anatomy - p. 727 129. Biopsy - p. 726.e1 130. Viral Hepatitis - p. 728 131. Drug-Induced and Toxic Liver Injury - p. 739 132. Steatosis and Steatohepatitis - p. 744 133. Cholestasis, Biliary Diseases, and Autoimmune Hepatitis - p. 750 134. Cirrhosis - p. 761 135. Childhood Disorders and Disorders of Metabolism - p. 762 136. Disorders of Copper and Iron Metabolism - p. 769 137. Fibropolycystic Diseases (Ductal Plate Malformation) - p. 772 138. Vascular Disorders - p. 775 139. Liver Disease in Pregnancy - p. 777 140. Liver Involvement in Systemic Diseases - p. 777 141. Liver Pathology in Organ Transplantation - p. 781 142. References - p. 785 143. 20 Liver - p. 803 144. Abstract - p. 803 145. Hepatic Tumors and Tumorlike Conditions - p. 804 146. Bile Duct Tumors and Tumorlike Conditions - p. 819 147. Mesenchymal Tumors and Tumorlike Conditions - p. 824 148. Malignant Lymphoma and Related Lesions - p. 829 149. Other Primary Tumors and Tumorlike Conditions - p. 831 150. Metastatic Tumors - p. 831 151. References - p. 833 152. 21 Gallbladder and Extrahepatic Bile Ducts - p. 844 153. 22 Pancreas and Ampullary Region - p. 886 154. Abstract - p. 886 155. Pancreas - p. 887 156. Ampullary Region - p. 921 157. References - p. 923 158. Section 5 Genitourinary Pathology - p. 933 159. 23 Kidney - p. 936 160. Abstract - p. 936 161. Renal Biopsy - p. 936.e1 162. Normal Structure of the Glomerulus - p. 938 163. Classification of Glomerular Disease - p. 940 164. Glomerular Lesions Associated With the Nephrotic Syndrome - p. 940 165. Glomerular Lesions Associated With the Syndrome of Acute Nephritis - p. 958 166. Glomerular Lesions Associated With Vascular Diseases - p. 973 167. Renal Diseases of Pregnancy - p. 979 168. Hereditary Glomerular Diseases - p. 980 169. Renal Transplant Pathology - p. 984 170. Tubulointerstitial Diseases - p. 989 171. Renal Vascular Disease - p. 995 172. Radiation Nephropathy - p. 998 173. Cystic Diseases of the Kidney - p. 998 174. References - p. 1002 175. 24 Kidney - p. 1014 176. Abstract - p. 1014 177. Pediatric Tumors and Tumorlike Conditions - p. 1015 178. Adult Tumors and Tumorlike Conditions - p. 1025 179. References - p. 1049 180. 25 Bladder - p. 1066 181. 26 Prostate and Seminal Vesicles - p. 1097 182. Abstract - p. 1097 183. Prostate - p. 1098 184. Prostatic Urethra - p. 1121 185. Seminal Vesicles and Cowper's Glands - p. 1121 186. References - p. 1122 187. 27 Testis and Testicular Adnexa - p. 1135 188. Abstract - p. 1135 189. Testis - p. 1136 190. Testicular Adnexa - p. 1157 191. References - p. 1164 192. 28 Penis and Scrotum - p. 1175 193. 29 Adrenal Gland and Other Paraganglia - p. 1190 194. Section 6 Female Reproductive System - p. 1221 195. 30 Vulva - p. 1224 196. 31 Vagina - p. 1248 197. 32 Uterus - p. 1260 198. Abstract - p. 1260 199. Normal Anatomy - p. 1261 200. Remnants and Ectopias - p. 1261 201. Squamous and Other Metaplasias - p. 1260.e1 202. Inflammatory Lesions - p. 1263 203. Non-Neoplastic Glandular Lesions - p. 1263 204. Non-Neoplastic Stromal Lesions (Including Endometriosis and Related Processes) - p. 1265 205. Human Papilloma Virus and the Lower Female Genital Tract - p. 1266 206. Tumors - p. 1267 207. References - p. 1284 208. 33 Uterus - p. 1294 209. Abstract - p. 1294 210. Normal Anatomy - p. 1295 211. Effects of Hormone Administration - p. 1296 212. Endometritis - p. 1297 213. Metaplasia - p. 1298 214. Adenomyosis and Endometriosis - p. 1300 215. Dysfunctional Uterine Bleeding - p. 1302 216. Endometrial Hyperplasia Without Atypia, Atypical Hyperplasia, and Variants - p. 1303 217. Curettage and Biopsy - p. 1305 218. Tumors - p. 1306 219. References - p. 1340 220. 34 Fallopian Tube - p. 1356 221. 35 Ovary - p. 1367 222. Abstract - p. 1367 223. Normal Anatomy - p. 1368 224. Gonadal Dysgenesis - p. 1367.e1 225. Cysts, Stromal Hyperplasia, and Other Non-Neoplastic Lesions - p. 1369 226. Inflammation - p. 1373 227. Endometriosis - p. 1374 228. Tumors - p. 1374 229. References - p. 1417 230. Section 7 Breast - p. 1431 231. 36 Breast - p. 1434 232. Abstract - p. 1434 233. Normal Anatomy - p. 1435 234. Ectopia - p. 1436 235. Inflammatory and Related Lesions - p. 1437 236. Benign Breast Disease - p. 1440 237. Intraductal Proliferative Lesions and Nonproliferative Changes - p. 1440 238. Fibroepithelial Lesions - p. 1447 239. Adenosis and Sclerosing Lesions - p. 1451 240. Papillary Lesions - p. 1456 241. Nipple Lesions - p. 1462 242. Carcinoma - p. 1464 243. Salivary Gland and Skin Adnexal-Type Tumors (Including Myoepithelial Tumors) - p. 1503 244. Stromal and Vascular Tumors and Tumorlike Conditions - p. 1504 245. Lymphoid Tumors and Tumorlike Conditions - p. 1506 246. Other Primary Tumors and Tumorlike Conditions - p. 1507 247. Metastatic Tumors - p. 1509 248. Breast Diseases in Children and Adolescents - p. 1510 249. Breast Diseases in Males - p. 1511 250. References - p. 1512 251. Section 8 Hematopathology - p. 1527 252. 37 Lymph Nodes - p. 1530 253. Abstract - p. 1530 254. Normal Anatomy - p. 1531 255. Lymph Node Evaluation - p. 1530.e1 256. Primary Immunodeficiencies - p. 1538 257. Patterns of Hyperplasia - p. 1539 258. Inflammatory/Hyperplastic Diseases - p. 1543 259. Malignant Lymphoma - p. 1561 260. Tumors of the Accessory Immune System - p. 1594 261. Vascular Tumors and Tumorlike Conditions - p. 1597 262. Other Primary Tumors and Tumorlike Conditions - p. 1598 263. Lymph Node Inclusions - p. 1601 264. Other Non-Neoplastic Lesions - p. 1604 265. Metastatic Tumors - p. 1605 266. References - p. 1610 267. 38 Spleen - p. 1632 268. 39 Bone Marrow - p. 1658 269. Abstract - p. 1658 270. Biopsy Procedure and Processing of Specimen - p. 1659 271. Immunohistochemistry - p. 1660 272. Normocellular Bone Marrow - p. 1662 273. Alterations in Cellularity - p. 1663 274. Osteopetrosis - p. 1665 275. Bone Marrow Necrosis - p. 1665 276. Inflammatory Disorders - p. 1666 277. Human Immunodeficiency Virus Syndrome (HIV, AIDS) - p. 1669 278. Leukemias and Related Disorders - p. 1670 279. Systemic Mastocytosis - p. 1684 280. Mature B-Cell Neoplasms - p. 1687 281. Non-Hodgkin Lymphoma - p. 1693 282. Benign Lymphocytic Aggregates - p. 1703 283. Hodgkin Lymphoma - p. 1704 284. Histiocytic Disorders - p. 1706 285. Plasma Cell Dyscrasias - p. 1709 286. Systemic Polyclonal B-Immunoblastic Proliferation - p. 1716 287. Metastatic Tumors - p. 1717 288. Lipid Storage Diseases - p. 1719 289. Hematopoietic Cell Transplantation - p. 1721 290. Acknowledgment - p. 1724 291. References - p. 1724 292. Section 9 Bone and Soft Tissue Pathology - p. 1737 293. 40 Bone and Joints - p. 1740 294. Abstract - p. 1740 295. Bone - p. 1741 296. Joints and Related Structures - p. 1789 297. References - p. 1797 298. 41 Soft Tissues - p. 1810 299. Abstract - p. 1810 300. Normal Anatomy - p. 1811 301. Infections and Hematomas - p. 1810.e1 302. Tumors - p. 1810.e1 303. References - p. 1892 304. Section 10 Cardiovascular Pathology - p. 1914 305. 42 Cardiovascular System - p. 1916 306. Section 11 Central Nervous System - p. 1945 307. 43 Central Nervous System - p. 1948 308. Abstract - p. 1948 309. Normal Anatomy - p. 1949 310. Developmental Abnormalities - p. 1948.e1 311. Cerebrovascular Disorders - p. 1955 312. Inflammatory Diseases - p. 1962 313. Infectious Diseases - p. 1967 314. Primary Tumors - p. 1977 315. Secondary/Metastatic Tumors - p. 2059 316. Acknowledgments - p. 2061 317. References - p. 2061 318. 44 Pituitary Gland - p. 2086 319. 45 Eye and Ocular Adnexa - p. 2112 320. Index - p. I-1