In this issue of Critical Care Clinics, guest editors Drs. Manu Shankar-Hari and Lieuwe D. J. Bos bring their considerable expertise to the topic of Sepsis and Systemic Inflammatory Syndromes. Sepsis and systemic inflammatory syndromes represent life-threatening medical emergencies and remain leading causes of morbidity and mortality worldwide. Advances in early detection, biomarker development, and targeted immunomodulatory therapies continue to reshape clinical practice, making this issue especially timely for clinicians in emergency medicine, critical care, and multiple medical specialties.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Post-Sepsis Syndrome after Critical Illness: Epidemiology and Long-term Outcomes - p. 683 9. Immune-Mediated Inflammatory Diseases and the Critically Ill - p. 701 10. Early Management of Sepsis - p. 719 11. Post-Sepsis Syndrome: From Pathogenesis Toward Novel Management Strategies - p. 745 12. Principles of Immunotherapeutic Drug Discovery for Severe Infections Using Extreme Phenotypes - p. 763 13. The Nonimmune Aspects of Sepsis - p. 777 14. Antimicrobial Resistance in Patients with Sepsis - p. 795 15. Sepsis and the Immunocompromised Host - p. 821 16. Real-time Subgrouping of Sepsis and Systemic Inflammatory Syndromes - p. 839 17. The Immunometabolic Architecture of Sepsis: Bridging Cellular Bioenergetics and Systemic Immune Dysregulation - p. 857 18. Immunosuppression in the Pathophysiology of Sepsis - p. 875 19. Sepsis and Systemic Inflammatory Syndromes: Effects of Systemic Inflammation on the Brain - p. 891
In this issue of Critical Care Clinics, guest editors Drs. Manu Shankar-Hari and Lieuwe D. J. Bos bring their considerable expertise to the topic of Sepsis and Systemic Inflammatory Syndromes. Sepsis and systemic inflammatory syndromes represent life-threatening medical emergencies and remain leading causes of morbidity and mortality worldwide. Advances in early detection, biomarker development, and targeted immunomodulatory therapies continue to reshape clinical practice, making this issue especially timely for clinicians in emergency medicine, critical care, and multiple medical specialties.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Post-Sepsis Syndrome after Critical Illness: Epidemiology and Long-term Outcomes - p. 683 9. Immune-Mediated Inflammatory Diseases and the Critically Ill - p. 701 10. Early Management of Sepsis - p. 719 11. Post-Sepsis Syndrome: From Pathogenesis Toward Novel Management Strategies - p. 745 12. Principles of Immunotherapeutic Drug Discovery for Severe Infections Using Extreme Phenotypes - p. 763 13. The Nonimmune Aspects of Sepsis - p. 777 14. Antimicrobial Resistance in Patients with Sepsis - p. 795 15. Sepsis and the Immunocompromised Host - p. 821 16. Real-time Subgrouping of Sepsis and Systemic Inflammatory Syndromes - p. 839 17. The Immunometabolic Architecture of Sepsis: Bridging Cellular Bioenergetics and Systemic Immune Dysregulation - p. 857 18. Immunosuppression in the Pathophysiology of Sepsis - p. 875 19. Sepsis and Systemic Inflammatory Syndromes: Effects of Systemic Inflammation on the Brain - p. 891
