Significant biological differences exist between men and women that contribute to sex-specific differences in cardiovascular disease (CVD) risk factors, pathophysiology, presentation, response to therapy, and prognosis. It is essential for clinicians to be cognizant of these sex-specific differences in order to reduce the disparity in diagnosis and management of cardiovascular diseases in both genders.Sex Differences in Cardiac Disease provides a timely review of the contemporary data on these sex-specific differences in pathophysiology, clinical presentation, diagnostic evaluation, and management of cardiovascular diseases that fills a void for clinicians in practice and training. With contributions from renowned experts in the field and guideline writers, the text provides a state-of-the-art review of each topic encompassing the full spectrum of CVD in men and women. Sex-specific guideline-based recommendations are highlighted when available. Tailored to meet the needs of the busy clinicians and researchers, this text provides concise practical data to care for men and women at risk for or with CVD. The book serves as an essential resource for researchers, cardiologists, obstetricians, gynecologists, internists, family practitioners, nurse practitioners and physician assistants, and respective trainees who treat men and women with CVD.
1. Section I: Introduction - p. xvii 2. Chapter 1. Introduction: Past, Present, and Future of Heart Disease in Men and Women - p. 3 3. Section II: Epidemiology and Prevalence - p. 6 4. Chapter 2. Epidemiology and Prevalence - p. 9 5. Section III: Ischemic Heart Disease - p. 29 6. Chapter 3. Prevention of Cardiovascular Disease - p. 33 7. Chapter 4. Acute Coronary Syndrome - p. 62 8. Chapter 5. Spontaneous Coronary Artery Dissection - p. 75 9. Chapter 6. Interventions in Ischemic Heart Disease - p. 95 10. Chapter 7. Stable Ischemic Heart Disease - p. 109 11. Chapter 8. Coronary Microvascular Dysfunction - p. 141 12. Chapter 9. Myocardial Infarction With Nonobstructive Coronary Disease - p. 163 13. Section IV: Heart Failure - p. 182 14. Chapter 10. Heart Failure With Reduced Ejection Fraction - p. 190 15. Chapter 11. Heart Failure With Preserved Ejection Fraction - p. 201 16. Chapter 12. Pulmonary Arterial Hypertension - p. 223 17. Chapter 13. Takotsubo Syndrome - p. 235 18. Chapter 14. Peripartum Cardiomyopathy - p. 251 19. Section V: Valvular Heart Disease - p. 274 20. Chapter 15. Valvular Heart Disease - p. 277 21. Section VI: Arrhythmias - p. 305 22. Chapter 16. Atrial Fibrillation - p. 309 23. Chapter 17. Ventricular Arrhythmias - p. 331 24. Chapter 18. Role of ICD and CRT - p. 350 25. Section VII: Vascular Disease - p. 362 26. Chapter 19. Peripheral Arterial Disease - p. 368 27. Section VIII: Congenital Heart Disease - p. 379 28. Chapter 20. Congenital Heart Disease - p. 390 29. Section IX: Pregnancy-Related Heart Disease - p. 399 30. Chapter 21. Pregnancy and Cardiovascular Disease - p. 411 31. Chapter 22. Unique Features of Cardiovascular Pharmacology in Pregnancy and Lactation - p. 443 32. Section X: Cardiac Disorders Unique or More Specific to Women - p. 478 33. Chapter 23. CardioRheumatology - p. 481 34. Chapter 24. CardioOncology - p. 505 35. Chapter 25. Sex Hormones and Their Impact on Cardiovascular Health - p. 554 36. Section XI: Psychological Health in CVD - p. 565 37. Chapter 26. Psychosocial Issues in Cardiovascular Disease - p. 573 38. Section XII: Pharmacotherapy Considerations in Men and Women - p. 592 39. Chapter 27. Cardiovascular Medications - p. 601 40. Section XIII: Current Challenges, Opportunities, and Next Steps for Clinicians - p. 642 41. Chapter 28. Disparity in Care Across the CVD Spectrum - p. 645 42. Chapter 29. Women’s Heart Programs - p. 671 43. Index - p. 689
Significant biological differences exist between men and women that contribute to sex-specific differences in cardiovascular disease (CVD) risk factors, pathophysiology, presentation, response to therapy, and prognosis. It is essential for clinicians to be cognizant of these sex-specific differences in order to reduce the disparity in diagnosis and management of cardiovascular diseases in both genders.Sex Differences in Cardiac Disease provides a timely review of the contemporary data on these sex-specific differences in pathophysiology, clinical presentation, diagnostic evaluation, and management of cardiovascular diseases that fills a void for clinicians in practice and training. With contributions from renowned experts in the field and guideline writers, the text provides a state-of-the-art review of each topic encompassing the full spectrum of CVD in men and women. Sex-specific guideline-based recommendations are highlighted when available. Tailored to meet the needs of the busy clinicians and researchers, this text provides concise practical data to care for men and women at risk for or with CVD. The book serves as an essential resource for researchers, cardiologists, obstetricians, gynecologists, internists, family practitioners, nurse practitioners and physician assistants, and respective trainees who treat men and women with CVD.
1. Section I: Introduction - p. xvii 2. Chapter 1. Introduction: Past, Present, and Future of Heart Disease in Men and Women - p. 3 3. Section II: Epidemiology and Prevalence - p. 6 4. Chapter 2. Epidemiology and Prevalence - p. 9 5. Section III: Ischemic Heart Disease - p. 29 6. Chapter 3. Prevention of Cardiovascular Disease - p. 33 7. Chapter 4. Acute Coronary Syndrome - p. 62 8. Chapter 5. Spontaneous Coronary Artery Dissection - p. 75 9. Chapter 6. Interventions in Ischemic Heart Disease - p. 95 10. Chapter 7. Stable Ischemic Heart Disease - p. 109 11. Chapter 8. Coronary Microvascular Dysfunction - p. 141 12. Chapter 9. Myocardial Infarction With Nonobstructive Coronary Disease - p. 163 13. Section IV: Heart Failure - p. 182 14. Chapter 10. Heart Failure With Reduced Ejection Fraction - p. 190 15. Chapter 11. Heart Failure With Preserved Ejection Fraction - p. 201 16. Chapter 12. Pulmonary Arterial Hypertension - p. 223 17. Chapter 13. Takotsubo Syndrome - p. 235 18. Chapter 14. Peripartum Cardiomyopathy - p. 251 19. Section V: Valvular Heart Disease - p. 274 20. Chapter 15. Valvular Heart Disease - p. 277 21. Section VI: Arrhythmias - p. 305 22. Chapter 16. Atrial Fibrillation - p. 309 23. Chapter 17. Ventricular Arrhythmias - p. 331 24. Chapter 18. Role of ICD and CRT - p. 350 25. Section VII: Vascular Disease - p. 362 26. Chapter 19. Peripheral Arterial Disease - p. 368 27. Section VIII: Congenital Heart Disease - p. 379 28. Chapter 20. Congenital Heart Disease - p. 390 29. Section IX: Pregnancy-Related Heart Disease - p. 399 30. Chapter 21. Pregnancy and Cardiovascular Disease - p. 411 31. Chapter 22. Unique Features of Cardiovascular Pharmacology in Pregnancy and Lactation - p. 443 32. Section X: Cardiac Disorders Unique or More Specific to Women - p. 478 33. Chapter 23. CardioRheumatology - p. 481 34. Chapter 24. CardioOncology - p. 505 35. Chapter 25. Sex Hormones and Their Impact on Cardiovascular Health - p. 554 36. Section XI: Psychological Health in CVD - p. 565 37. Chapter 26. Psychosocial Issues in Cardiovascular Disease - p. 573 38. Section XII: Pharmacotherapy Considerations in Men and Women - p. 592 39. Chapter 27. Cardiovascular Medications - p. 601 40. Section XIII: Current Challenges, Opportunities, and Next Steps for Clinicians - p. 642 41. Chapter 28. Disparity in Care Across the CVD Spectrum - p. 645 42. Chapter 29. Women’s Heart Programs - p. 671 43. Index - p. 689