Stem Cells in Medicine, Volume 199 in the Progress in Molecular Biology and Translational Science series, provides the most topical and informative research in the field of stem cells. Sections in this new release update on an Introduction to stem cells, Stem cell engineering, Xeno-free culture and proliferation of hPSCs on 2D biomaterials, 3D scaffold preparation for stem cell culture and differentiation, GMP grade production of hPSCs, Human hepatic stem cell assay, Cardiomyocyte cell sheets derived from hPSCs and muscle cells for myocardial infarction treatment, Stem cell therapy for osteoarthritis, hPSC-derived RPE transplantation for the treatment of macular degeneration, and much more.
The book provides not only fundamental aspects and cultural and production methods of stem cells, but also the critical engineering aspects of stem cells such as drug screening using hepatocytes and disease treatment by transplantation of retinal pigment epithelium and cardiomyocytes which are derived from human pluripotent stem cells.
1. Chapter One: Introduction to stem cells - p. 3 2. Chapter Two: Engineered adult stem cells: Current clinical trials status of disease treatment - p. 33 3. Chapter Three: Xeno-free culture and proliferation of hPSCs on 2D biomaterials - p. 62 4. Chapter Four: Stem cell culture and differentiation in 3-D scaffolds - p. 109 5. Clinical application - p. 127 6. Chapter Five: Current trends and promising clinical utility of IPSC-derived MSC (iMSC) - p. 131 7. Chapter Six: Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells - p. 156 8. Chapter Seven: Cardiac cell sheet engineering for regenerative medicine and tissue modeling - p. 179 9. Chapter Eight: Mesenchymal stem cells in osteoarthritis: The need for translation into clinical therapy - p. 200 10. Chapter Nine: hPSC-derived RPE transplantation for the treatment of macular degeneration - p. 227 11. Chapter Ten: Universal and hypoimmunogenic pluripotent stem cells for clinical usage - p. 271 12. Chapter Eleven: Clinical usage of dental stem cells and their derived extracellular vesicles - p. 297 13. Chapter Twelve: Vascularization of cutaneous wounds by stem cells - p. 327 14. Chapter Thirteen: Application of IPSC and Müller glia derivatives in retinal degenerative diseases - p. 350 15. Chapter Fourteen: Pluripotent stem cells as a therapy for type 1 diabetes - p. 363 16. Chapter Fifteen: Stem cell challenges and opportunities - p. 379 17. Index - p. 395
Stem Cells in Medicine, Volume 199 in the Progress in Molecular Biology and Translational Science series, provides the most topical and informative research in the field of stem cells. Sections in this new release update on an Introduction to stem cells, Stem cell engineering, Xeno-free culture and proliferation of hPSCs on 2D biomaterials, 3D scaffold preparation for stem cell culture and differentiation, GMP grade production of hPSCs, Human hepatic stem cell assay, Cardiomyocyte cell sheets derived from hPSCs and muscle cells for myocardial infarction treatment, Stem cell therapy for osteoarthritis, hPSC-derived RPE transplantation for the treatment of macular degeneration, and much more.
The book provides not only fundamental aspects and cultural and production methods of stem cells, but also the critical engineering aspects of stem cells such as drug screening using hepatocytes and disease treatment by transplantation of retinal pigment epithelium and cardiomyocytes which are derived from human pluripotent stem cells.
1. Chapter One: Introduction to stem cells - p. 3 2. Chapter Two: Engineered adult stem cells: Current clinical trials status of disease treatment - p. 33 3. Chapter Three: Xeno-free culture and proliferation of hPSCs on 2D biomaterials - p. 62 4. Chapter Four: Stem cell culture and differentiation in 3-D scaffolds - p. 109 5. Clinical application - p. 127 6. Chapter Five: Current trends and promising clinical utility of IPSC-derived MSC (iMSC) - p. 131 7. Chapter Six: Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells - p. 156 8. Chapter Seven: Cardiac cell sheet engineering for regenerative medicine and tissue modeling - p. 179 9. Chapter Eight: Mesenchymal stem cells in osteoarthritis: The need for translation into clinical therapy - p. 200 10. Chapter Nine: hPSC-derived RPE transplantation for the treatment of macular degeneration - p. 227 11. Chapter Ten: Universal and hypoimmunogenic pluripotent stem cells for clinical usage - p. 271 12. Chapter Eleven: Clinical usage of dental stem cells and their derived extracellular vesicles - p. 297 13. Chapter Twelve: Vascularization of cutaneous wounds by stem cells - p. 327 14. Chapter Thirteen: Application of IPSC and Müller glia derivatives in retinal degenerative diseases - p. 350 15. Chapter Fourteen: Pluripotent stem cells as a therapy for type 1 diabetes - p. 363 16. Chapter Fifteen: Stem cell challenges and opportunities - p. 379 17. Index - p. 395
