Stem Cells in Neurotoxicology, Volume Twelve in the Advances in Neurotoxicology series, presents interesting chapters written by an international board of authors. Chapters in this new release include Brain organoids as a translational model of human developmental neurotoxicity, Self-organizing human neuronal cultures in the modeling of environmental impacts on learning and intelligence, Utilization of human stem cell/neural progenitor tests to examine neurotoxic impacts on differentiation, Characterization of neuronal and other cellular sub-types in human stem cell cortical neuron differentiations, Utility of human stem cell models to study persistent neurotoxicity, and Utility of human stem cell models to study chronic neurotoxicity.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Contributors - p. xi 6. Preface - p. xiii 7. Chapter One: The long road to the development of stem cells as a model for central nervous system health and disease - p. 1 8. Chapter Two: Immortalized neuronal lines versus human induced pluripotent stem cell-derived neurons as in vitro toxicology models - p. 47 9. Chapter Three: Brain organoids as a translational model of human developmental neurotoxicity - p. 83 10. Chapter Four: Self-organizing human neuronal cultures in the modeling of environmental impacts on learning and intelligence - p. 107 11. Chapter Five: Utilization of human stem cells to examine neurotoxic impacts on differentiation - p. 137 12. Chapter Six: The role of stem cells in the study and treatment of neurodegenerative diseases with environmental etiology - p. 173 13. Chapter Seven: The use of human iPSC-derived neuronal cultures for the study of persistent neurotoxic effects - p. 207 14. Chapter Eight: Simple and reproducible directed differentiation of cortical neural cells from hiPSCs in chemically defined media for toxicological studies - p. 237
Stem Cells in Neurotoxicology, Volume Twelve in the Advances in Neurotoxicology series, presents interesting chapters written by an international board of authors. Chapters in this new release include Brain organoids as a translational model of human developmental neurotoxicity, Self-organizing human neuronal cultures in the modeling of environmental impacts on learning and intelligence, Utilization of human stem cell/neural progenitor tests to examine neurotoxic impacts on differentiation, Characterization of neuronal and other cellular sub-types in human stem cell cortical neuron differentiations, Utility of human stem cell models to study persistent neurotoxicity, and Utility of human stem cell models to study chronic neurotoxicity.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Contributors - p. xi 6. Preface - p. xiii 7. Chapter One: The long road to the development of stem cells as a model for central nervous system health and disease - p. 1 8. Chapter Two: Immortalized neuronal lines versus human induced pluripotent stem cell-derived neurons as in vitro toxicology models - p. 47 9. Chapter Three: Brain organoids as a translational model of human developmental neurotoxicity - p. 83 10. Chapter Four: Self-organizing human neuronal cultures in the modeling of environmental impacts on learning and intelligence - p. 107 11. Chapter Five: Utilization of human stem cells to examine neurotoxic impacts on differentiation - p. 137 12. Chapter Six: The role of stem cells in the study and treatment of neurodegenerative diseases with environmental etiology - p. 173 13. Chapter Seven: The use of human iPSC-derived neuronal cultures for the study of persistent neurotoxic effects - p. 207 14. Chapter Eight: Simple and reproducible directed differentiation of cortical neural cells from hiPSCs in chemically defined media for toxicological studies - p. 237
