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Descripción

Steroids in the Laboratory and Clinical Practice covers both basic chemistry and therapeutic application of steroids in a single source. The comprehensive reference addresses the specificity of steroid determinations to clarify confusion arising from the laboratory results. The book covers important advancements in the field and is a valuable addition in the literature addressing all existing knowledge gaps. This is a must have reference for pathologists, laboratorians, endocrinologists, analytical/clinical chemists and biochemists.

  • Addresses the normal production of steroids and concentrations found in biological fluids and tissues
  • Presents the changes in steroid concentrations at life events as reference points for clinical investigations
  • Reviews the genetic disorders of steroids in relation to specific enzyme changes and clinical presentation

1. 2.4.1 Introduction - p. 425 2. 2.4.2 Examination of column, thin layer and paper chromatograms - p. 425 3. 2.4.3 GLC detectors - p. 356 4. 2.4.4 Detectors for HPLC - p. 356 5. 2.4.5 Immunoassay of steroids - p. 357 6. 2.4.6 Mass spectrometry - p. 370 7. 2.4.7 Analysis of unconjugated neutral steroids - p. 406 8. 2.4.8 Plasma steroid profiles - p. 413 9. 2.4.9 Steroids in urine - p. 421 10. 2.4.10 Assay validation - p. 424 11. 2.4.11 Selected applications - p. 443 12. 2.4.12 Data analysis of MS data - p. 449 13. 2.4.13 Steroid conjugates (glucuronides and sulfates) - p. 453 14. 2.4.14 New techniques - p. 454 15. 2.4.15 Point of care testing - p. 458 16. 2.4.16 Summary and future developments - p. 458 17. 2.4.17 Further reading - p. 459 18. Appendix. References for interference in steroid immunoassays - p. 460 19. References - p. 463 20. Books - p. 471 21. Chapter 2.5. Normal concentrations of steroids and their regulators in blood - p. 473 22. Chapter 2.6. Steroids in urine, other fluids and tissues - p. 548 23. Chapter 2.7. Confirmatory tests in steroid endocrinology - p. 613 24. Part III: Steroids in clinical practice - p. 641 25. Chapter 3.1.1. Cortisol excess states - p. 649 26. Chapter 3.1.2. Cortisol deficiency - p. 699 27. Chapter 3.2.1. Hypergonadism - p. 753 28. Chapter 3.2.2. Hypogonadism - p. 829 29. Chapter 3.3.1. Mineralocorticoid excess - p. 879 30. Chapter 3.3.2. Hypoaldosteronism, pseudohypoaldosteronism and salt loss - p. 935 31. Index - p. 975

Descripcion
Descripción

Steroids in the Laboratory and Clinical Practice covers both basic chemistry and therapeutic application of steroids in a single source. The comprehensive reference addresses the specificity of steroid determinations to clarify confusion arising from the laboratory results. The book covers important advancements in the field and is a valuable addition in the literature addressing all existing knowledge gaps. This is a must have reference for pathologists, laboratorians, endocrinologists, analytical/clinical chemists and biochemists.

  • Addresses the normal production of steroids and concentrations found in biological fluids and tissues
  • Presents the changes in steroid concentrations at life events as reference points for clinical investigations
  • Reviews the genetic disorders of steroids in relation to specific enzyme changes and clinical presentation

1. 2.4.1 Introduction - p. 425 2. 2.4.2 Examination of column, thin layer and paper chromatograms - p. 425 3. 2.4.3 GLC detectors - p. 356 4. 2.4.4 Detectors for HPLC - p. 356 5. 2.4.5 Immunoassay of steroids - p. 357 6. 2.4.6 Mass spectrometry - p. 370 7. 2.4.7 Analysis of unconjugated neutral steroids - p. 406 8. 2.4.8 Plasma steroid profiles - p. 413 9. 2.4.9 Steroids in urine - p. 421 10. 2.4.10 Assay validation - p. 424 11. 2.4.11 Selected applications - p. 443 12. 2.4.12 Data analysis of MS data - p. 449 13. 2.4.13 Steroid conjugates (glucuronides and sulfates) - p. 453 14. 2.4.14 New techniques - p. 454 15. 2.4.15 Point of care testing - p. 458 16. 2.4.16 Summary and future developments - p. 458 17. 2.4.17 Further reading - p. 459 18. Appendix. References for interference in steroid immunoassays - p. 460 19. References - p. 463 20. Books - p. 471 21. Chapter 2.5. Normal concentrations of steroids and their regulators in blood - p. 473 22. Chapter 2.6. Steroids in urine, other fluids and tissues - p. 548 23. Chapter 2.7. Confirmatory tests in steroid endocrinology - p. 613 24. Part III: Steroids in clinical practice - p. 641 25. Chapter 3.1.1. Cortisol excess states - p. 649 26. Chapter 3.1.2. Cortisol deficiency - p. 699 27. Chapter 3.2.1. Hypergonadism - p. 753 28. Chapter 3.2.2. Hypogonadism - p. 829 29. Chapter 3.3.1. Mineralocorticoid excess - p. 879 30. Chapter 3.3.2. Hypoaldosteronism, pseudohypoaldosteronism and salt loss - p. 935 31. Index - p. 975

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Ficha Técnica