Strategies and Tactics in Organic Synthesis, Volume 15, provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project present the excitement of conception, the frustration of failure and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project.
Readers will be educated, challenged and inspired by these accounts, which portray the idea that triumphs do not come without challenges. This innovative approach also helps illustrate how challenges to further advance the science and art of organic synthesis can be overcome, driving the field forward to meet the demands of society by discovering new reactions, creating new designs and building molecules with atom and step economies that provide functional solutions to create a better world.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Front Matter - p. iii 5. Front Matter - p. iii 6. Copyright - p. iii 7. Dedication - p. iii 8. Contributors - p. iii 9. Preface - p. xvii 10. Chapter 1: Amaryllidaceae isocarbostyril alkaloids - p. 1 11. Chapter 2: Enzymatic dihydroxylation of aromatic compounds: Nature's unique reaction and its impact on the synthesis of natural products - p. 53 12. Chapter 3: Intermolecular oxidopyrylium [5 + 2] cycloaddition chemistry and its application toward the synthesis and study of highly oxygenated troponoids - p. 99 13. Chapter 4: Aryne-mediated construction of fluorene skeletons and its applications to total synthesis of selaginpulvilins - p. 149 14. Chapter 5: Cycloisomerizations across three states: the total synthesis of gelsenicine - p. 177 15. Chapter 6: Tetrapetalones ruminations, trials and tribulations - p. 211 16. Chapter 7: The synthesis of herqulines B and C - p. 247 17. Chapter 8: First total synthesis of the dimeric naphthoquinonopyrano-γ-lactone natural product (−)-crisamicin A. How procrastination may be of help in binaphthyl synthesis - p. 281 18. Chapter 9: Strategies and discoveries leading to the synthesis of trichoaurantianolide natural products - p. 335 19. Chapter 10: 4-exo-dig cyclocarbopalladation, discovery and application in the synthesis of complex polycyclic molecules - p. 365 20. Index - p. 415
Strategies and Tactics in Organic Synthesis, Volume 15, provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project present the excitement of conception, the frustration of failure and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project.
Readers will be educated, challenged and inspired by these accounts, which portray the idea that triumphs do not come without challenges. This innovative approach also helps illustrate how challenges to further advance the science and art of organic synthesis can be overcome, driving the field forward to meet the demands of society by discovering new reactions, creating new designs and building molecules with atom and step economies that provide functional solutions to create a better world.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Front Matter - p. iii 5. Front Matter - p. iii 6. Copyright - p. iii 7. Dedication - p. iii 8. Contributors - p. iii 9. Preface - p. xvii 10. Chapter 1: Amaryllidaceae isocarbostyril alkaloids - p. 1 11. Chapter 2: Enzymatic dihydroxylation of aromatic compounds: Nature's unique reaction and its impact on the synthesis of natural products - p. 53 12. Chapter 3: Intermolecular oxidopyrylium [5 + 2] cycloaddition chemistry and its application toward the synthesis and study of highly oxygenated troponoids - p. 99 13. Chapter 4: Aryne-mediated construction of fluorene skeletons and its applications to total synthesis of selaginpulvilins - p. 149 14. Chapter 5: Cycloisomerizations across three states: the total synthesis of gelsenicine - p. 177 15. Chapter 6: Tetrapetalones ruminations, trials and tribulations - p. 211 16. Chapter 7: The synthesis of herqulines B and C - p. 247 17. Chapter 8: First total synthesis of the dimeric naphthoquinonopyrano-γ-lactone natural product (−)-crisamicin A. How procrastination may be of help in binaphthyl synthesis - p. 281 18. Chapter 9: Strategies and discoveries leading to the synthesis of trichoaurantianolide natural products - p. 335 19. Chapter 10: 4-exo-dig cyclocarbopalladation, discovery and application in the synthesis of complex polycyclic molecules - p. 365 20. Index - p. 415
