Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.
Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.
1. Introduction - p. 101 2. Occurrence of poly-glycosidic iridoids in plants - p. 102 3. Chemophenetic value of poly-glycosidic iridoids - p. 145 4. Biological effects of poly-glycosidic iridoids - p. 146 5. Conclusion - p. 165 6. Chapter 5. Recent advances in oxylipin-driven repair mechanisms in vascular dysfunction-related diseases - p. 193 7. Chapter 6. Biotechnological approaches to the production of commercially important cardiac glycosides from Digitalis L. (foxglove) - p. 235 8. Chapter 7. Starch-based antioxidant formulations for pharmaceutical purposes - p. 279 9. Natural antioxidant compounds - p. 279 10. Natural sources of antioxidant compounds - p. 280 11. Food loss and waste as sources of antioxidant compounds - p. 282 12. Methods for the obtention of antioxidant-rich ingredients for pharmaceutical formulations - p. 283 13. Drying as a pretreatment for extraction of antioxidant compounds - p. 283 14. Extraction methods of antioxidant compounds - p. 283 15. Ultrasound-assisted extraction - p. 285 16. Microwave-assisted extraction - p. 303 17. High-pressure extraction: supercritical fluids extraction, pressurized liquids extraction, and subcritical water extraction - p. 304 18. Concentration and fractionation methods - p. 306 19. Particle formation processes - p. 307 20. Antioxidant products containing starch - p. 312 21. Liquid formulations - p. 312 22. Gels - p. 313 23. Films - p. 313 24. Powders and granules - p. 315 25. Capsules - p. 315 26. Tablets - p. 315 27. Characterization of pharmaceutical formulations with antioxidants - p. 316 28. Antioxidant quantification - p. 317 29. Antioxidant capacity - p. 321 30. Other critical quality characterizations - p. 323 31. Concluding remark - p. 324 32. Chapter 8. Emerging tools to study phenolic compounds from tropical fruits: Extraction, identification, protection, and computational approaches - p. 347 33. Chapter 9. Strigolactones: From plant hormones to medicinal agents - p. 385 34. Chapter 10. Natural products as potential therapeutic agents against microplastic-induced neurodegenerative disease - p. 425 35. Chapter 11. Recent developments in the treatment of leishmaniasis: Natural compounds, drug targets, in silico molecular docking approaches, and nanocarriers - p. 461 36. Chapter 12. Phenolic compounds from marine invertebrates: Bioprospecting and chemical synthesis - p. 495 37. Index - p. 525
Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.
Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.
1. Introduction - p. 101 2. Occurrence of poly-glycosidic iridoids in plants - p. 102 3. Chemophenetic value of poly-glycosidic iridoids - p. 145 4. Biological effects of poly-glycosidic iridoids - p. 146 5. Conclusion - p. 165 6. Chapter 5. Recent advances in oxylipin-driven repair mechanisms in vascular dysfunction-related diseases - p. 193 7. Chapter 6. Biotechnological approaches to the production of commercially important cardiac glycosides from Digitalis L. (foxglove) - p. 235 8. Chapter 7. Starch-based antioxidant formulations for pharmaceutical purposes - p. 279 9. Natural antioxidant compounds - p. 279 10. Natural sources of antioxidant compounds - p. 280 11. Food loss and waste as sources of antioxidant compounds - p. 282 12. Methods for the obtention of antioxidant-rich ingredients for pharmaceutical formulations - p. 283 13. Drying as a pretreatment for extraction of antioxidant compounds - p. 283 14. Extraction methods of antioxidant compounds - p. 283 15. Ultrasound-assisted extraction - p. 285 16. Microwave-assisted extraction - p. 303 17. High-pressure extraction: supercritical fluids extraction, pressurized liquids extraction, and subcritical water extraction - p. 304 18. Concentration and fractionation methods - p. 306 19. Particle formation processes - p. 307 20. Antioxidant products containing starch - p. 312 21. Liquid formulations - p. 312 22. Gels - p. 313 23. Films - p. 313 24. Powders and granules - p. 315 25. Capsules - p. 315 26. Tablets - p. 315 27. Characterization of pharmaceutical formulations with antioxidants - p. 316 28. Antioxidant quantification - p. 317 29. Antioxidant capacity - p. 321 30. Other critical quality characterizations - p. 323 31. Concluding remark - p. 324 32. Chapter 8. Emerging tools to study phenolic compounds from tropical fruits: Extraction, identification, protection, and computational approaches - p. 347 33. Chapter 9. Strigolactones: From plant hormones to medicinal agents - p. 385 34. Chapter 10. Natural products as potential therapeutic agents against microplastic-induced neurodegenerative disease - p. 425 35. Chapter 11. Recent developments in the treatment of leishmaniasis: Natural compounds, drug targets, in silico molecular docking approaches, and nanocarriers - p. 461 36. Chapter 12. Phenolic compounds from marine invertebrates: Bioprospecting and chemical synthesis - p. 495 37. Index - p. 525
