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α-Tertiary Amines en Route to Natural Products presents the multistep synthesis of natural products using schematic diagrams. This approach provides a quick-and-easy way to review and understand new and novel synthetic strategies to construct structural frameworks of natural products. The book covers the class of natural products bearing the α,α-disubstituted α-amino acid motif. Featured natural product molecules include Altemicidin, Amathaspiramide (A-F), Kaitocephalin, Lactacystin, Salinosporamide, Manzacidins (A,C), Neooxazolomycin, Sphingofungins (E,F), (1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid (ACPD), Total synthesis of cephalotaxine and related molecules, α-amino acids based natural products, α amino acid based natural products and Tetrodotoxin.

This book is ideal for chemists working in the area of organic synthesis, especially those who are involved in the development of new, efficient and novel methodologies for natural product synthesis.

  • Outlines synthetic strategies for natural products bearing α-tertiary amines and α,α-disubstituted α-amino acid motif
  • Describes multistep synthetic routes that highlight key steps
  • Covers asymmetric and diastereoselective synthetic approaches towards targeted natural products
  • Illustrates multistep synthetic routes related to -amino acids based natural products and -amino acids based natural products

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Preface - p. iii 7. Natural products with α-tertiary amine - p. 1 8. Chapter 2. Altemicidin - p. 5 9. Chapter 3. Amathaspiramides A–F - p. 11 10. Chapter 4. Cephalotaxine - p. 19 11. Chapter 5. Kaitocephalin - p. 67 12. Chapter 6. Lactacystin - p. 81 13. Chapter 7. Salinosporamide A - p. 105 14. Chapter 8. Manzacidins - p. 119 15. Chapter 9. Neooxazolomycin - p. 139 16. Chapter 10. Sphingofungins - p. 149 17. Chapter 11. (−)-FR901483 and TAN1251 (A-D) - p. 167 18. Chapter 12. Synthetic approach to the TAN1251 alkaloids - p. 187 19. (1S,3R)-1-Aminocyclopentane-1,3-diarboxylic acid (ACPD) - p. 199 20. Chapter 14. Tetrodotoxin - p. 203 21. Abbreviations - p. 223 22. Index - p. 225

Descripcion
Descripción

α-Tertiary Amines en Route to Natural Products presents the multistep synthesis of natural products using schematic diagrams. This approach provides a quick-and-easy way to review and understand new and novel synthetic strategies to construct structural frameworks of natural products. The book covers the class of natural products bearing the α,α-disubstituted α-amino acid motif. Featured natural product molecules include Altemicidin, Amathaspiramide (A-F), Kaitocephalin, Lactacystin, Salinosporamide, Manzacidins (A,C), Neooxazolomycin, Sphingofungins (E,F), (1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid (ACPD), Total synthesis of cephalotaxine and related molecules, α-amino acids based natural products, α amino acid based natural products and Tetrodotoxin.

This book is ideal for chemists working in the area of organic synthesis, especially those who are involved in the development of new, efficient and novel methodologies for natural product synthesis.

  • Outlines synthetic strategies for natural products bearing α-tertiary amines and α,α-disubstituted α-amino acid motif
  • Describes multistep synthetic routes that highlight key steps
  • Covers asymmetric and diastereoselective synthetic approaches towards targeted natural products
  • Illustrates multistep synthetic routes related to -amino acids based natural products and -amino acids based natural products

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Preface - p. iii 7. Natural products with α-tertiary amine - p. 1 8. Chapter 2. Altemicidin - p. 5 9. Chapter 3. Amathaspiramides A–F - p. 11 10. Chapter 4. Cephalotaxine - p. 19 11. Chapter 5. Kaitocephalin - p. 67 12. Chapter 6. Lactacystin - p. 81 13. Chapter 7. Salinosporamide A - p. 105 14. Chapter 8. Manzacidins - p. 119 15. Chapter 9. Neooxazolomycin - p. 139 16. Chapter 10. Sphingofungins - p. 149 17. Chapter 11. (−)-FR901483 and TAN1251 (A-D) - p. 167 18. Chapter 12. Synthetic approach to the TAN1251 alkaloids - p. 187 19. (1S,3R)-1-Aminocyclopentane-1,3-diarboxylic acid (ACPD) - p. 199 20. Chapter 14. Tetrodotoxin - p. 203 21. Abbreviations - p. 223 22. Index - p. 225

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