Now Ettinger’s trusted, all-in-one veterinary resource is even better! Trusted by small animal veterinarians for more than 45 years, Ettinger’s Textbook of Veterinary Internal Medicine adds new content on the field’s leading issues and trends to its unmatched, “gold standard coverage of the diagnosis and treatment of medical problems of dogs and cats. Coverage begins with the basics of veterinary medicine, followed by sections on differential diagnosis for chief complaints and for clinicopathologic abnormalities, and continues with techniques, minimally invasive interventional therapies, critical care, toxicology, diseases by body system, and comorbidities. Clinical information is presented in a way that reflects the practitioner’s thought process.
1. 169. Immunologic and Hematologic Disease: Introduction and Drug Therapy - p. 853 2. 170. Coagulation Testing - p. 857 3. 171. Hyper- and Hypocoagulable States - p. 863 4. 172. Nonregenerative Anemia - p. 870 5. 173. Erythrocytosis and Primary Polycythemia - p. 878 6. 174. Immune-Mediated Hemolytic Anemia and Other Regenerative Anemias - p. 881 7. 175. Immune Thrombocytopenia, von Willebrand Disease, and Other Platelet Disorders - p. 883 8. 176. Nonneoplastic White Blood Cell Disorders and Pancytopenia - p. 903 9. 177. Immune-Mediated Polyarthritis and Other Polyarthropathies - p. 908 10. 178. Immune-Mediated Dermatologic Diseases - p. 915 11. 179. Systemic Lupus Erythematosus - p. 922 12. 180. Immunodeficiencies - p. 926 13. 181. Vasculitides - p. 931 14. 182. Diseases of the Spleen - p. 934 15. Section XI Infectious Disease - p. 948.e1 16. General - p. 948.e1 17. 183. Does This Dog or Cat Have an Infectious Disease? - p. 949 18. 184. Laboratory Diagnosis of Infectious Disease - p. 954 19. 185. Companion Animal Vaccinations - p. 961 20. 186. Hospital-Associated (Nosocomial) Infections - p. 967 21. Bacterial Diseases - p. 970 22. 187. Lyme Disease - p. 971 23. 188. Mycobacterial Infections, Actinomycosis, and Nocardiosis - p. 976 24. 189. Brucellosis - p. 982 25. 190. Tetanus and Botulism - p. 985 26. 191. Bartonellosis - p. 989 27. 192. Leptospirosis - p. 997 28. 193. Ehrlichiosis, Anaplasmosis, Rocky Mountain Spotted Fever, and Neorickettsiosis - p. 1003 29. 194. Hemotropic Mycoplasmas - p. 1011 30. 195. Enteric Bacterial Diseases - p. 1017 31. Protozoal Diseases - p. 1022.e1 32. 196. Enteric Protozoan Diseases - p. 1023 33. 197. Systemic Protozoal Diseases - p. 1030 34. Viral Diseases - p. 1039.e1 35. 198. Feline Immunodeficiency Virus Infection - p. 1037 36. 199. Feline Leukemia Virus Infection - p. 1042 37. 200. Coronavirus Infection - p. 1050 38. 201. Canine and Feline Parvovirus Infection - p. 1060 39. 202. Rabies - p. 1065 40. 203. Canine Infectious Respiratory Disease Complex - p. 1071 41. 204. Canine Distemper - p. 1075 42. 205. Feline Upper Respiratory Infections - p. 1079 43. 206. Emerging Viral Infections of Cats - p. 1085 44. Fungal Diseases - p. 1087 45. 207. Cryptococcosis - p. 1088 46. 208. Coccidioidomycosis - p. 1092 47. 209. Blastomycosis and Histoplasmosis - p. 1096 48. 210. Sinonasal and Sino-Orbital Aspergillosis - p. 1107 49. 211. Disseminated Invasive Aspergillosis and Systemic Mold Infections - p. 1112 50. Volume 2 - p. 1115 51. Section XII Respiratory Disease - p. 1115 52. 212. Clinical Evaluation of the Respiratory Tract - p. 1117 53. 213. Diseases of the Nose, Sinuses, and Nasopharynx - p. 1128 54. 214. Laryngeal Diseases - p. 1152 55. 215. Large Airway Diseases - p. 1158 56. 216. Small Airway Diseases - p. 1173 57. 217. Pulmonary Parenchymal Diseases - p. 1175 58. 218. Pulmonary Hypertension - p. 1198 59. 219. Pulmonary Thromboembolism - p. 1205 60. 220. Pleural Space Diseases - p. 1208 61. 221. Aerodigestive Disorders - p. 1217 62. 222. Diseases of the Mediastinum, Chest Wall, and Diaphragm - p. 1221 63. Section XIII Comorbidities - p. 1231 64. 223. Heart Disease and Kidney Disease - p. 1233 65. 224. Comorbidities: Diabetes Mellitus and Corticosteroid-Responsive Disease - p. 1239 66. 225. Feline Triaditis - p. 1248 67. 226. Obesity and Immobility - p. 1253 68. 227. Concurrent Infection and Immune Suppression - p. 1256 69. Section XIV Cardiovascular Disease - p. 1261 70. 228. Pathophysiology of Heart Failure - p. 1263 71. 229. Heart Failure: Diagnosis and Management - p. 1274 72. 230. Cardiac Arrhythmias - p. 1288 73. 231. Congenital Heart Disease - p. 1313 74. 232. Valvular Heart Diseases of Adult Dogs and Cats - p. 1348 75. 233. Myocardial Diseases of Dogs - p. 1367 76. 234. Feline Myocardial Diseases - p. 1377 77. 235. Pericardial Diseases - p. 1409 78. 236. Systemic Hypertension - p. 1422 79. 237. Heartworm Disease in Dogs and Cats - p. 1434 80. 238. Arterial Thromboembolic Disease - p. 1457 81. 239. Venous and Lymphatic Disorders - p. 1463 82. Section XV Neurologic Disease - p. 1477 83. 240. Neurophysiology - p. 1470 84. 241. Neurologic Examination and Neuroanatomic Diagnosis - p. 1483 85. 242. Inflammatory, Infectious, and Other Multifocal Brain Diseases - p. 1495 86. 243. Vascular Brain Diseases - p. 1508 87. 244. Developmental, Degenerative and Metabolic Brain Diseases and Sleep Disorders - p. 1513 88. 245. Neoplastic Brain Diseases - p. 1535 89. 246. Traumatic Brain Disease - p. 1545 90. 247. Epilepsy - p. 1552 91. 248. Vestibular Disease - p. 1559 92. 249. Cranial Neuropathies - p. 1565 93. 250. Spinal Cord Diseases: Congenital (Developmental), Inflammatory, and Degenerative Disorders - p. 1570 94. 251. Spinal Cord Diseases: Traumatic, Vascular, and Neoplastic - p. 1591 95. 252. Peripheral Neuropathies - p. 1603 96. 253. Neuromuscular Junction Disorders - p. 1608 97. 254. Autonomic Nervous System Disorders - p. 1612 98. 255. Unique Feline Neurologic Disorders - p. 1615 99. 256. Physical Therapy and Rehabilitation - p. 1616 100. Section XVI Gastrointestinal Disease - p. 1620 101. 257. Laboratory Evaluation of the Gastrointestinal Tract - p. 1631 102. 258. Oral Cavity and Salivary Gland Disorders - p. 1637 103. 259. Pharyngeal and Esophageal Diseases - p. 1644 104. 260. Host-Microbial Interactions in Gastrointestinal Health - p. 1659 105. 261. Gastric Diseases - p. 1667 106. 262. Small Intestinal Diseases - p. 1683 107. 263. Diseases of the Large Intestine - p. 1728 108. 264. Rectoanal Diseases - p. 1754 109. 265. Peritoneal Diseases - p. 1766 110. Section XVII Hepatobiliary Disease - p. 1772 111. 266. Pathophysiology of Liver Disease - p. 1773 112. 267. Congenital Vascular Liver Diseases - p. 1782 113. 268. Congenital Ductal Plate Abnormalities - p. 1801 114. 269. Acute Toxic and Other Parenchymal Liver Disease - p. 1809 115. 270. Chronic Hepatitis in Dogs - p. 1822 116. 271. Chronic Hepatic Diseases in Cats - p. 1830 117. 272. Infectious Biliary Tract and Gallbladder Disease - p. 1837 118. 273. Non-infectious Biliary Tract and Gallbladder Disease - p. 1840 119. 274. Vacuolar Hepatopathies - p. 1847 120. 275. Neoplasia of the Liver and Biliary Tree - p. 1852 121. Section XVIII Pancreatic Disease - p. 1858 122. 276. Pancreatitis: Etiology, Pathogenesis, and Pathophysiologic Consequences - p. 1859 123. 277. Pancreatitis in Dogs: Diagnosis and Management - p. 1862 124. 278. Pancreatitis in Cats - p. 1869 125. 279. Exocrine Pancreatic Insufficiency and Rare Conditions of the Exocrine Pancreas - p. 1875 126. Section XIX Endocrine Disease - p. 1880 127. 280. Growth Hormone Disorders in Cats - p. 1881 128. 281. Canine Growth Hormone Disorders - p. 1890 129. 282. Diabetes Insipidus - p. 1895 130. 283. Primary Hyperparathyroidism - p. 1901 131. 284. Hypoparathyroidism - p. 1916 132. 285. Hypothyroidism in Dogs - p. 1920 133. 286. Feline Hypothyroidism - p. 1935 134. 287. Hyperthyroidism in Cats - p. 1940 135. 288. Canine Hyperthyroidism - p. 1952 136. 289. Insulin-Secreting Tumors - p. 1959 137. 290. Diabetic Ketoacidosis and the Hyperosmolar Hyperglycemic State - p. 1966 138. 291. Diabetes Mellitus in Dogs - p. 1974 139. 292. Diabetes Mellitus in Cats - p. 1990 140. 293. Hyperadrenocorticism (Cushing's Syndrome) in Dogs - p. 2004 141. 294. Feline Hyperadrenocorticism - p. 2022 142. 295. Non-Cortisol-Secreting Adrenocortical Tumors - p. 2028 143. 296. Hypoadrenocorticism - p. 2036 144. 297. Gastrointestinal Endocrinology - p. 2045 145. 298. Pheochromocytoma - p. 2050 146. Section XX Renal Disease - p. 2056 147. 299. Clinical Approach and Laboratory Evaluation of Renal Disease - p. 2057 148. 300. Acute Kidney Injury - p. 2073 149. 301. Chronic Kidney Disease - p. 2089 150. 302. Glomerular Diseases - p. 2107 151. 303. Renal Tubular Diseases - p. 2120 152. 304. Pyelonephritis - p. 2127 153. 305. Familial and Congenital Renal Diseases of Cats and Dogs - p. 2130 154. Section XXI Lower Urinary Tract Disease - p. 2136 155. 306. Ureteral Disorders - p. 2137 156. 307. Lower Urinary Tract Infections - p. 2144 157. 308. Lower Urinary Tract Urolithiasis in Dogs - p. 2148 158. 309. Lower Urinary Tract Urolithiasis—Feline - p. 2158 159. 310. Diseases of Abnormal Micturition - p. 2164 160. 311. Feline Idiopathic/Interstitial Cystitis - p. 2171 161. 312. Urethral Disorders - p. 2179 162. 313. Congenital Lower Urinary Tract Disorders - p. 2183 163. 314. Prostatic Diseases - p. 2190 164. 315. Reproductive Disorders in Neutered Male and Female Dogs and Cats - p. 2199 165. Section XXII Cancer - p. 2206 166. 316. Tumor Biology - p. 2207 167. 317. Principles and Practice of Chemotherapy - p. 2211 168. 318. Principles and Practice of Radiation Oncology - p. 2215 169. 319. Cancer Immunotherapy - p. 2224 170. 320. Molecular Targeted Therapy - p. 2227 171. 321. Complications of Cancer Therapy - p. 2230 172. 322. Hematopoietic Tumors - p. 2240 173. 323. Tumors of the Skin - p. 2255 174. 324. Soft Tissue Sarcomas - p. 2262 175. 325. Hemangiosarcoma - p. 2270 176. 326. Primary Bone Tumors in Dogs - p. 2280 177. 327. Mast Cell Disease - p. 2288 178. 328. Canine and Feline Histiocytic Diseases - p. 2295 179. 329. Mammary Gland Tumors - p. 2301 180. 330. Urogenital Tumors - p. 2306 181. 331. Paraneoplastic Syndromes - p. 2315 182. Index - p. I-1
Now Ettinger’s trusted, all-in-one veterinary resource is even better! Trusted by small animal veterinarians for more than 45 years, Ettinger’s Textbook of Veterinary Internal Medicine adds new content on the field’s leading issues and trends to its unmatched, “gold standard coverage of the diagnosis and treatment of medical problems of dogs and cats. Coverage begins with the basics of veterinary medicine, followed by sections on differential diagnosis for chief complaints and for clinicopathologic abnormalities, and continues with techniques, minimally invasive interventional therapies, critical care, toxicology, diseases by body system, and comorbidities. Clinical information is presented in a way that reflects the practitioner’s thought process.
1. 169. Immunologic and Hematologic Disease: Introduction and Drug Therapy - p. 853 2. 170. Coagulation Testing - p. 857 3. 171. Hyper- and Hypocoagulable States - p. 863 4. 172. Nonregenerative Anemia - p. 870 5. 173. Erythrocytosis and Primary Polycythemia - p. 878 6. 174. Immune-Mediated Hemolytic Anemia and Other Regenerative Anemias - p. 881 7. 175. Immune Thrombocytopenia, von Willebrand Disease, and Other Platelet Disorders - p. 883 8. 176. Nonneoplastic White Blood Cell Disorders and Pancytopenia - p. 903 9. 177. Immune-Mediated Polyarthritis and Other Polyarthropathies - p. 908 10. 178. Immune-Mediated Dermatologic Diseases - p. 915 11. 179. Systemic Lupus Erythematosus - p. 922 12. 180. Immunodeficiencies - p. 926 13. 181. Vasculitides - p. 931 14. 182. Diseases of the Spleen - p. 934 15. Section XI Infectious Disease - p. 948.e1 16. General - p. 948.e1 17. 183. Does This Dog or Cat Have an Infectious Disease? - p. 949 18. 184. Laboratory Diagnosis of Infectious Disease - p. 954 19. 185. Companion Animal Vaccinations - p. 961 20. 186. Hospital-Associated (Nosocomial) Infections - p. 967 21. Bacterial Diseases - p. 970 22. 187. Lyme Disease - p. 971 23. 188. Mycobacterial Infections, Actinomycosis, and Nocardiosis - p. 976 24. 189. Brucellosis - p. 982 25. 190. Tetanus and Botulism - p. 985 26. 191. Bartonellosis - p. 989 27. 192. Leptospirosis - p. 997 28. 193. Ehrlichiosis, Anaplasmosis, Rocky Mountain Spotted Fever, and Neorickettsiosis - p. 1003 29. 194. Hemotropic Mycoplasmas - p. 1011 30. 195. Enteric Bacterial Diseases - p. 1017 31. Protozoal Diseases - p. 1022.e1 32. 196. Enteric Protozoan Diseases - p. 1023 33. 197. Systemic Protozoal Diseases - p. 1030 34. Viral Diseases - p. 1039.e1 35. 198. Feline Immunodeficiency Virus Infection - p. 1037 36. 199. Feline Leukemia Virus Infection - p. 1042 37. 200. Coronavirus Infection - p. 1050 38. 201. Canine and Feline Parvovirus Infection - p. 1060 39. 202. Rabies - p. 1065 40. 203. Canine Infectious Respiratory Disease Complex - p. 1071 41. 204. Canine Distemper - p. 1075 42. 205. Feline Upper Respiratory Infections - p. 1079 43. 206. Emerging Viral Infections of Cats - p. 1085 44. Fungal Diseases - p. 1087 45. 207. Cryptococcosis - p. 1088 46. 208. Coccidioidomycosis - p. 1092 47. 209. Blastomycosis and Histoplasmosis - p. 1096 48. 210. Sinonasal and Sino-Orbital Aspergillosis - p. 1107 49. 211. Disseminated Invasive Aspergillosis and Systemic Mold Infections - p. 1112 50. Volume 2 - p. 1115 51. Section XII Respiratory Disease - p. 1115 52. 212. Clinical Evaluation of the Respiratory Tract - p. 1117 53. 213. Diseases of the Nose, Sinuses, and Nasopharynx - p. 1128 54. 214. Laryngeal Diseases - p. 1152 55. 215. Large Airway Diseases - p. 1158 56. 216. Small Airway Diseases - p. 1173 57. 217. Pulmonary Parenchymal Diseases - p. 1175 58. 218. Pulmonary Hypertension - p. 1198 59. 219. Pulmonary Thromboembolism - p. 1205 60. 220. Pleural Space Diseases - p. 1208 61. 221. Aerodigestive Disorders - p. 1217 62. 222. Diseases of the Mediastinum, Chest Wall, and Diaphragm - p. 1221 63. Section XIII Comorbidities - p. 1231 64. 223. Heart Disease and Kidney Disease - p. 1233 65. 224. Comorbidities: Diabetes Mellitus and Corticosteroid-Responsive Disease - p. 1239 66. 225. Feline Triaditis - p. 1248 67. 226. Obesity and Immobility - p. 1253 68. 227. Concurrent Infection and Immune Suppression - p. 1256 69. Section XIV Cardiovascular Disease - p. 1261 70. 228. Pathophysiology of Heart Failure - p. 1263 71. 229. Heart Failure: Diagnosis and Management - p. 1274 72. 230. Cardiac Arrhythmias - p. 1288 73. 231. Congenital Heart Disease - p. 1313 74. 232. Valvular Heart Diseases of Adult Dogs and Cats - p. 1348 75. 233. Myocardial Diseases of Dogs - p. 1367 76. 234. Feline Myocardial Diseases - p. 1377 77. 235. Pericardial Diseases - p. 1409 78. 236. Systemic Hypertension - p. 1422 79. 237. Heartworm Disease in Dogs and Cats - p. 1434 80. 238. Arterial Thromboembolic Disease - p. 1457 81. 239. Venous and Lymphatic Disorders - p. 1463 82. Section XV Neurologic Disease - p. 1477 83. 240. Neurophysiology - p. 1470 84. 241. Neurologic Examination and Neuroanatomic Diagnosis - p. 1483 85. 242. Inflammatory, Infectious, and Other Multifocal Brain Diseases - p. 1495 86. 243. Vascular Brain Diseases - p. 1508 87. 244. Developmental, Degenerative and Metabolic Brain Diseases and Sleep Disorders - p. 1513 88. 245. Neoplastic Brain Diseases - p. 1535 89. 246. Traumatic Brain Disease - p. 1545 90. 247. Epilepsy - p. 1552 91. 248. Vestibular Disease - p. 1559 92. 249. Cranial Neuropathies - p. 1565 93. 250. Spinal Cord Diseases: Congenital (Developmental), Inflammatory, and Degenerative Disorders - p. 1570 94. 251. Spinal Cord Diseases: Traumatic, Vascular, and Neoplastic - p. 1591 95. 252. Peripheral Neuropathies - p. 1603 96. 253. Neuromuscular Junction Disorders - p. 1608 97. 254. Autonomic Nervous System Disorders - p. 1612 98. 255. Unique Feline Neurologic Disorders - p. 1615 99. 256. Physical Therapy and Rehabilitation - p. 1616 100. Section XVI Gastrointestinal Disease - p. 1620 101. 257. Laboratory Evaluation of the Gastrointestinal Tract - p. 1631 102. 258. Oral Cavity and Salivary Gland Disorders - p. 1637 103. 259. Pharyngeal and Esophageal Diseases - p. 1644 104. 260. Host-Microbial Interactions in Gastrointestinal Health - p. 1659 105. 261. Gastric Diseases - p. 1667 106. 262. Small Intestinal Diseases - p. 1683 107. 263. Diseases of the Large Intestine - p. 1728 108. 264. Rectoanal Diseases - p. 1754 109. 265. Peritoneal Diseases - p. 1766 110. Section XVII Hepatobiliary Disease - p. 1772 111. 266. Pathophysiology of Liver Disease - p. 1773 112. 267. Congenital Vascular Liver Diseases - p. 1782 113. 268. Congenital Ductal Plate Abnormalities - p. 1801 114. 269. Acute Toxic and Other Parenchymal Liver Disease - p. 1809 115. 270. Chronic Hepatitis in Dogs - p. 1822 116. 271. Chronic Hepatic Diseases in Cats - p. 1830 117. 272. Infectious Biliary Tract and Gallbladder Disease - p. 1837 118. 273. Non-infectious Biliary Tract and Gallbladder Disease - p. 1840 119. 274. Vacuolar Hepatopathies - p. 1847 120. 275. Neoplasia of the Liver and Biliary Tree - p. 1852 121. Section XVIII Pancreatic Disease - p. 1858 122. 276. Pancreatitis: Etiology, Pathogenesis, and Pathophysiologic Consequences - p. 1859 123. 277. Pancreatitis in Dogs: Diagnosis and Management - p. 1862 124. 278. Pancreatitis in Cats - p. 1869 125. 279. Exocrine Pancreatic Insufficiency and Rare Conditions of the Exocrine Pancreas - p. 1875 126. Section XIX Endocrine Disease - p. 1880 127. 280. Growth Hormone Disorders in Cats - p. 1881 128. 281. Canine Growth Hormone Disorders - p. 1890 129. 282. Diabetes Insipidus - p. 1895 130. 283. Primary Hyperparathyroidism - p. 1901 131. 284. Hypoparathyroidism - p. 1916 132. 285. Hypothyroidism in Dogs - p. 1920 133. 286. Feline Hypothyroidism - p. 1935 134. 287. Hyperthyroidism in Cats - p. 1940 135. 288. Canine Hyperthyroidism - p. 1952 136. 289. Insulin-Secreting Tumors - p. 1959 137. 290. Diabetic Ketoacidosis and the Hyperosmolar Hyperglycemic State - p. 1966 138. 291. Diabetes Mellitus in Dogs - p. 1974 139. 292. Diabetes Mellitus in Cats - p. 1990 140. 293. Hyperadrenocorticism (Cushing's Syndrome) in Dogs - p. 2004 141. 294. Feline Hyperadrenocorticism - p. 2022 142. 295. Non-Cortisol-Secreting Adrenocortical Tumors - p. 2028 143. 296. Hypoadrenocorticism - p. 2036 144. 297. Gastrointestinal Endocrinology - p. 2045 145. 298. Pheochromocytoma - p. 2050 146. Section XX Renal Disease - p. 2056 147. 299. Clinical Approach and Laboratory Evaluation of Renal Disease - p. 2057 148. 300. Acute Kidney Injury - p. 2073 149. 301. Chronic Kidney Disease - p. 2089 150. 302. Glomerular Diseases - p. 2107 151. 303. Renal Tubular Diseases - p. 2120 152. 304. Pyelonephritis - p. 2127 153. 305. Familial and Congenital Renal Diseases of Cats and Dogs - p. 2130 154. Section XXI Lower Urinary Tract Disease - p. 2136 155. 306. Ureteral Disorders - p. 2137 156. 307. Lower Urinary Tract Infections - p. 2144 157. 308. Lower Urinary Tract Urolithiasis in Dogs - p. 2148 158. 309. Lower Urinary Tract Urolithiasis—Feline - p. 2158 159. 310. Diseases of Abnormal Micturition - p. 2164 160. 311. Feline Idiopathic/Interstitial Cystitis - p. 2171 161. 312. Urethral Disorders - p. 2179 162. 313. Congenital Lower Urinary Tract Disorders - p. 2183 163. 314. Prostatic Diseases - p. 2190 164. 315. Reproductive Disorders in Neutered Male and Female Dogs and Cats - p. 2199 165. Section XXII Cancer - p. 2206 166. 316. Tumor Biology - p. 2207 167. 317. Principles and Practice of Chemotherapy - p. 2211 168. 318. Principles and Practice of Radiation Oncology - p. 2215 169. 319. Cancer Immunotherapy - p. 2224 170. 320. Molecular Targeted Therapy - p. 2227 171. 321. Complications of Cancer Therapy - p. 2230 172. 322. Hematopoietic Tumors - p. 2240 173. 323. Tumors of the Skin - p. 2255 174. 324. Soft Tissue Sarcomas - p. 2262 175. 325. Hemangiosarcoma - p. 2270 176. 326. Primary Bone Tumors in Dogs - p. 2280 177. 327. Mast Cell Disease - p. 2288 178. 328. Canine and Feline Histiocytic Diseases - p. 2295 179. 329. Mammary Gland Tumors - p. 2301 180. 330. Urogenital Tumors - p. 2306 181. 331. Paraneoplastic Syndromes - p. 2315 182. Index - p. I-1
