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The Chlamydomonas Sourcebook, 3rd Edition

Cell Motility and Behavior (Volume 3)

The gold-standard reference introducing this multidisciplinary science, fully revised and updated with the latest discoveries

Originally published as the standalone Chlamydomonas Sourcebook, then expanded as the third volume in a three-part comprehensive gold-standard reference, The Chlamydomonas Sourcebook: Cell Motility and Behavior has been fully revised and updated to include the wealth of new resources for the Chlamydomonas community. Reflecting the significant advancement in the understanding of the role of basal bodies and cilia play in human diseases, this volume employs quantitative proteomics and mass spectroscopy as well as cryo EM tomography and single particle cryo EM. Other topics such as current insights on mitosis and cytokinesis, ciliary assembly and motility, intraflagellar transport, and more help build an understanding of human diseases of the cilium.

Cell Motility and Behavior presents the latest in research and best practices, making this a must-have resource for researchers and students working in plant science and photosynthesis, fertility, mammalian vision, and biochemistry; crop scientists; plant physiologists; and plant, molecular, and human disease biologists.

  • Provides an essential reference to a model species for the study of mechanisms of motility in free living cells 
  • Includes methods for Chlamydomonas motility research 
  • Includes a table listing the known proteins (with NCBI accession numbers) for each structure discussed, and the known mutations that affect each structure and process

1. Introduction to Volume 3 - p. xv 2. Landmark contributions of Chlamydomonas to understanding cilia - p. 1 3. Chapter 2. Basal bodies - p. 35 4. Chapter 3. The ciliary transition zone - p. 57 5. Chapter 4. Axonemal dyneins: genetics, structure, and motor activity - p. 79 6. Chapter 5. Axonemal dynein preassembly - p. 133 7. Chapter 6. Ciliary radial spokes - p. 157 8. Chlamydomonas ciliary central apparatus - p. 177 9. Chapter 8. I1/f dynein and the nexin–dynein regulatory complex form two hubs to control dynein activity and ciliary beating - p. 205 10. Chapter 9. Ciliary asymmetries and their role in ciliary motility - p. 231 11. The Chlamydomonas ciliary membrane and its dynamic properties - p. 247 12. Chapter 11. Physics and mechanics of ciliary beating - p. 273 13. Chapter 12. Intraflagellar transport - p. 307 14. Genetic control of cilia length in Chlamydomonas - p. 337 15. Chapter 14. Ciliary disassembly - p. 357 16. Chapter 15. Deciliation - p. 373 17. Chapter 16. The eyespot and behavioral light responses - p. 391 18. Ciliary adhesion and cilium-generated signaling during fertilization in Chlamydomonas - p. 421 19. Chapter 18. The cellular cytoskeleton - p. 433 20. Index - p. 447

Descripcion
Descripción

The Chlamydomonas Sourcebook, 3rd Edition

Cell Motility and Behavior (Volume 3)

The gold-standard reference introducing this multidisciplinary science, fully revised and updated with the latest discoveries

Originally published as the standalone Chlamydomonas Sourcebook, then expanded as the third volume in a three-part comprehensive gold-standard reference, The Chlamydomonas Sourcebook: Cell Motility and Behavior has been fully revised and updated to include the wealth of new resources for the Chlamydomonas community. Reflecting the significant advancement in the understanding of the role of basal bodies and cilia play in human diseases, this volume employs quantitative proteomics and mass spectroscopy as well as cryo EM tomography and single particle cryo EM. Other topics such as current insights on mitosis and cytokinesis, ciliary assembly and motility, intraflagellar transport, and more help build an understanding of human diseases of the cilium.

Cell Motility and Behavior presents the latest in research and best practices, making this a must-have resource for researchers and students working in plant science and photosynthesis, fertility, mammalian vision, and biochemistry; crop scientists; plant physiologists; and plant, molecular, and human disease biologists.

  • Provides an essential reference to a model species for the study of mechanisms of motility in free living cells 
  • Includes methods for Chlamydomonas motility research 
  • Includes a table listing the known proteins (with NCBI accession numbers) for each structure discussed, and the known mutations that affect each structure and process

1. Introduction to Volume 3 - p. xv 2. Landmark contributions of Chlamydomonas to understanding cilia - p. 1 3. Chapter 2. Basal bodies - p. 35 4. Chapter 3. The ciliary transition zone - p. 57 5. Chapter 4. Axonemal dyneins: genetics, structure, and motor activity - p. 79 6. Chapter 5. Axonemal dynein preassembly - p. 133 7. Chapter 6. Ciliary radial spokes - p. 157 8. Chlamydomonas ciliary central apparatus - p. 177 9. Chapter 8. I1/f dynein and the nexin–dynein regulatory complex form two hubs to control dynein activity and ciliary beating - p. 205 10. Chapter 9. Ciliary asymmetries and their role in ciliary motility - p. 231 11. The Chlamydomonas ciliary membrane and its dynamic properties - p. 247 12. Chapter 11. Physics and mechanics of ciliary beating - p. 273 13. Chapter 12. Intraflagellar transport - p. 307 14. Genetic control of cilia length in Chlamydomonas - p. 337 15. Chapter 14. Ciliary disassembly - p. 357 16. Chapter 15. Deciliation - p. 373 17. Chapter 16. The eyespot and behavioral light responses - p. 391 18. Ciliary adhesion and cilium-generated signaling during fertilization in Chlamydomonas - p. 421 19. Chapter 18. The cellular cytoskeleton - p. 433 20. Index - p. 447

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