The Complement FactsBook, Second Edition, provides in-depth insights and an overview of the components of the complement system. This new edition highlights the use of newly recommended complement nomenclature, covering new pathways and proteins and adding information on mouse homologs. It is a completely revised and updated edition containing entries on all components of the complement system, and is an excellent source of one-stop shopping for complement information and references. It is the most convenient compilation of biochemical, biological and molecular biology for complementologists and those new in the field.
This new edition is expanded to include relevant updates and topics that have evolved since the last edition was published, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families.
1. Chapter 1. Introduction - p. 1 2. Chapter 2. The Complement System - p. 7 3. Part I. Collectins - p. 20 4. Chapter 3. C1q - p. 23 5. Chapter 4. Mannose-Binding Lectin - p. 33 6. Chapter 5. Ficolins - p. 45 7. Chapter 6. The Collectins - p. 57 8. Part II. Serine Proteases - p. 65 9. Chapter 7. MASP-1 - p. 69 10. Chapter 8. MASP-2 - p. 79 11. Chapter 9. MASP-3 - p. 89 12. Chapter 10. C1r - p. 99 13. Chapter 11. C1s - p. 107 14. Chapter 12. Factor D - p. 117 15. Chapter 13. C2 - p. 127 16. Chapter 14. Factor B - p. 135 17. Chapter 15. Factor I - p. 147 18. Part III. C3 Family - p. 154 19. Chapter 16. C3 - p. 157 20. Chapter 17. C4 - p. 171 21. Chapter 18. C5 - p. 187 22. Part IV. Terminal Pathway Components - p. 201 23. Chapter 19. C6 - p. 205 24. Chapter 20. C7 - p. 213 25. Chapter 21. C8 - p. 221 26. Chapter 22. C9 - p. 231 27. Part V. Regulatory Proteins - p. 237 28. Chapter 23. C1 Inhibitor - p. 241 29. Chapter 24. C4b-Binding Protein - p. 251 30. Chapter 25. Decay-Accelerating Factor - p. 261 31. Chapter 26. Membrane Cofactor Protein - p. 271 32. Chapter 27. Properdin - p. 283 33. Chapter 28. CR1 - p. 295 34. Chapter 29. CRIg - p. 309 35. Chapter 30. Factor H and Factor H-like Protein 1 - p. 317 36. Chapter 31. Factor H-Related Proteins 1–5 - p. 329 37. Chapter 32. Clusterin - p. 341 38. Chapter 33. Vitronectin - p. 351 39. Chapter 34. CD59 - p. 361 40. Chapter 35. CSMD1 - p. 369 41. Part VI. Anaphylatoxin and Leucocyte Receptors - p. 381 42. Chapter 36. C3aR1 - p. 385 43. Chapter 37. C5aR1 - p. 397 44. Chapter 38. C5aR2 - p. 407 45. Chapter 39. C1q Receptors - p. 415 46. Chapter 40. CR2 - p. 423 47. Chapter 41. CR3 - p. 435 48. Chapter 42. CR4 - p. 451 49. Appendix A. Complement Nomenclature 2014 - p. 463 50. Index - p. 471
The Complement FactsBook, Second Edition, provides in-depth insights and an overview of the components of the complement system. This new edition highlights the use of newly recommended complement nomenclature, covering new pathways and proteins and adding information on mouse homologs. It is a completely revised and updated edition containing entries on all components of the complement system, and is an excellent source of one-stop shopping for complement information and references. It is the most convenient compilation of biochemical, biological and molecular biology for complementologists and those new in the field.
This new edition is expanded to include relevant updates and topics that have evolved since the last edition was published, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families.
1. Chapter 1. Introduction - p. 1 2. Chapter 2. The Complement System - p. 7 3. Part I. Collectins - p. 20 4. Chapter 3. C1q - p. 23 5. Chapter 4. Mannose-Binding Lectin - p. 33 6. Chapter 5. Ficolins - p. 45 7. Chapter 6. The Collectins - p. 57 8. Part II. Serine Proteases - p. 65 9. Chapter 7. MASP-1 - p. 69 10. Chapter 8. MASP-2 - p. 79 11. Chapter 9. MASP-3 - p. 89 12. Chapter 10. C1r - p. 99 13. Chapter 11. C1s - p. 107 14. Chapter 12. Factor D - p. 117 15. Chapter 13. C2 - p. 127 16. Chapter 14. Factor B - p. 135 17. Chapter 15. Factor I - p. 147 18. Part III. C3 Family - p. 154 19. Chapter 16. C3 - p. 157 20. Chapter 17. C4 - p. 171 21. Chapter 18. C5 - p. 187 22. Part IV. Terminal Pathway Components - p. 201 23. Chapter 19. C6 - p. 205 24. Chapter 20. C7 - p. 213 25. Chapter 21. C8 - p. 221 26. Chapter 22. C9 - p. 231 27. Part V. Regulatory Proteins - p. 237 28. Chapter 23. C1 Inhibitor - p. 241 29. Chapter 24. C4b-Binding Protein - p. 251 30. Chapter 25. Decay-Accelerating Factor - p. 261 31. Chapter 26. Membrane Cofactor Protein - p. 271 32. Chapter 27. Properdin - p. 283 33. Chapter 28. CR1 - p. 295 34. Chapter 29. CRIg - p. 309 35. Chapter 30. Factor H and Factor H-like Protein 1 - p. 317 36. Chapter 31. Factor H-Related Proteins 1–5 - p. 329 37. Chapter 32. Clusterin - p. 341 38. Chapter 33. Vitronectin - p. 351 39. Chapter 34. CD59 - p. 361 40. Chapter 35. CSMD1 - p. 369 41. Part VI. Anaphylatoxin and Leucocyte Receptors - p. 381 42. Chapter 36. C3aR1 - p. 385 43. Chapter 37. C5aR1 - p. 397 44. Chapter 38. C5aR2 - p. 407 45. Chapter 39. C1q Receptors - p. 415 46. Chapter 40. CR2 - p. 423 47. Chapter 41. CR3 - p. 435 48. Chapter 42. CR4 - p. 451 49. Appendix A. Complement Nomenclature 2014 - p. 463 50. Index - p. 471
