The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system. The chapters cover significant conceptual advances in the endocannabinoid field and shed light on the many brain disorders in which this biological system is involved.
Written by world-leading experts in the field, the topics covered in this book will have a positive impact on the area of molecular biology, including, but not limited to, cell biology, neuroscience, pharmacology, signaling, disease mechanisms, and therapeutics.
1. Introduction - p. xv 2. Chapter 1. Basic Mechanisms of Synthesis and Hydrolysis of Major Endocannabinoids - p. 1 3. Chapter 2. Cannabinoid Receptors and Their Signaling Mechanisms - p. 25 4. Introduction - p. 26 5. Endocannabinoid System - p. 28 6. Chapter 3. The Endocannabinoid System and Parkinson Disease - p. 63 7. Chapter 4. Putative Role of Endocannabinoids in Schizophrenia - p. 83 8. Chapter 5. The Endocannabinoid System and Human Brain Functions: Insight From Memory, Motor, and Mood Pathologies - p. 115 9. Endocannabinoid Activity in the Brain - p. 116 10. Endocannabinoids and Memory Dysfunction - p. 122 11. Endocannabinoids and Motor Dysfunction - p. 127 12. Endocannabinoids in Mood and Thought Dysfunction - p. 149 13. Conclusions - p. 161 14. Chapter 6. The Role of the Endocannabinoid System in Addiction - p. 187 15. Introduction - p. 187 16. The Endocannabinoid System: Overview - p. 188 17. Alcohol - p. 190 18. Nicotine - p. 196 19. Opioids - p. 205 20. Psychostimulants - p. 209 21. Cannabinoid - p. 215 22. Conclusions - p. 219 23. Index - p. 237
The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system. The chapters cover significant conceptual advances in the endocannabinoid field and shed light on the many brain disorders in which this biological system is involved.
Written by world-leading experts in the field, the topics covered in this book will have a positive impact on the area of molecular biology, including, but not limited to, cell biology, neuroscience, pharmacology, signaling, disease mechanisms, and therapeutics.
1. Introduction - p. xv 2. Chapter 1. Basic Mechanisms of Synthesis and Hydrolysis of Major Endocannabinoids - p. 1 3. Chapter 2. Cannabinoid Receptors and Their Signaling Mechanisms - p. 25 4. Introduction - p. 26 5. Endocannabinoid System - p. 28 6. Chapter 3. The Endocannabinoid System and Parkinson Disease - p. 63 7. Chapter 4. Putative Role of Endocannabinoids in Schizophrenia - p. 83 8. Chapter 5. The Endocannabinoid System and Human Brain Functions: Insight From Memory, Motor, and Mood Pathologies - p. 115 9. Endocannabinoid Activity in the Brain - p. 116 10. Endocannabinoids and Memory Dysfunction - p. 122 11. Endocannabinoids and Motor Dysfunction - p. 127 12. Endocannabinoids in Mood and Thought Dysfunction - p. 149 13. Conclusions - p. 161 14. Chapter 6. The Role of the Endocannabinoid System in Addiction - p. 187 15. Introduction - p. 187 16. The Endocannabinoid System: Overview - p. 188 17. Alcohol - p. 190 18. Nicotine - p. 196 19. Opioids - p. 205 20. Psychostimulants - p. 209 21. Cannabinoid - p. 215 22. Conclusions - p. 219 23. Index - p. 237
