The Eye; Volume Four; the latest release in the Stem Cell Innovation in Health and Disease series; addresses the recent data accumulated on the potential applications of stem cells to treat eye diseases. This volume highlights the recent development of cutting-edge in vitro and in vivo research tools and approaches; including human and murine organoid cultures; genetic editing in vitro and in vivo; human iPSC models of disease; haploid cells for genetic as well as compound screening paradigms; genetically engineered mice; and stem cell transplantation to cure eye diseases.
The volume is written for researchers and scientists in stem cell therapy; cell biology; regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. This is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album on the fast-moving field of regenerative medicine and stem cell therapeutics.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. vi 7. List of contributors - p. xiii 8. About the editors - p. xv 9. Foreword - p. xvii 10. Preface - p. xix 11. Epigraph - p. xxi 12. Chapter 1. Stem cell-based organoid cultures as innovative approaches for ocular repair and regeneration - p. 1 13. Chapter 2. Organoid-based modality of eye function and cellular processes - p. 43 14. Chapter 3. Leveraging neural crest pluripotency to extend retinal and craniofacial niches for building neurovascular organoids—a theranostic and drug development perspective - p. 55 15. Chapter 4. Role of stem cell engineering and or gene-editing technologies in eye diseases degeneration, and therapy - p. 119 16. Chapter 5. Stem cells and genetic engineering empower therapeutic development for blinding eye diseases - p. 139 17. Chapter 6. Human stem cell-derived retinal pigment epithelial cells for retinal regeneration: differentiation and clinical translation - p. 171 18. Chapter 7. Mesenchymal stem cells therapy for retinal diseases - p. 193 19. Chapter 8. Retinal cone photoreceptors from pluripotent stem cells for macular regeneration - p. 221 20. Chapter 9. Update on stem/progenitor cell-based clinical trials for eye disease - p. 243 21. Chapter 10. Stem cell innovation in eye disease, repair and regeneration: general conclusion, challenges and prospective - p. 273 22. Index - p. 281
The Eye; Volume Four; the latest release in the Stem Cell Innovation in Health and Disease series; addresses the recent data accumulated on the potential applications of stem cells to treat eye diseases. This volume highlights the recent development of cutting-edge in vitro and in vivo research tools and approaches; including human and murine organoid cultures; genetic editing in vitro and in vivo; human iPSC models of disease; haploid cells for genetic as well as compound screening paradigms; genetically engineered mice; and stem cell transplantation to cure eye diseases.
The volume is written for researchers and scientists in stem cell therapy; cell biology; regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. This is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album on the fast-moving field of regenerative medicine and stem cell therapeutics.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. vi 7. List of contributors - p. xiii 8. About the editors - p. xv 9. Foreword - p. xvii 10. Preface - p. xix 11. Epigraph - p. xxi 12. Chapter 1. Stem cell-based organoid cultures as innovative approaches for ocular repair and regeneration - p. 1 13. Chapter 2. Organoid-based modality of eye function and cellular processes - p. 43 14. Chapter 3. Leveraging neural crest pluripotency to extend retinal and craniofacial niches for building neurovascular organoids—a theranostic and drug development perspective - p. 55 15. Chapter 4. Role of stem cell engineering and or gene-editing technologies in eye diseases degeneration, and therapy - p. 119 16. Chapter 5. Stem cells and genetic engineering empower therapeutic development for blinding eye diseases - p. 139 17. Chapter 6. Human stem cell-derived retinal pigment epithelial cells for retinal regeneration: differentiation and clinical translation - p. 171 18. Chapter 7. Mesenchymal stem cells therapy for retinal diseases - p. 193 19. Chapter 8. Retinal cone photoreceptors from pluripotent stem cells for macular regeneration - p. 221 20. Chapter 9. Update on stem/progenitor cell-based clinical trials for eye disease - p. 243 21. Chapter 10. Stem cell innovation in eye disease, repair and regeneration: general conclusion, challenges and prospective - p. 273 22. Index - p. 281
