The Hidden World of Protein Aggregation, Volume 206 provides a comprehensive exploration of protein aggregation, uncovering the factors behind the formation of amorphous aggregates and ordered structures called amyloid fibrils. It delves into the advantages and disadvantages of protein aggregates, addressing topics such as cytotoxicity and disorders linked to misfolding. Specific chapters in this release include Protein Aggregation: An Overview, Pathways of Amyloid Fibril Formation and Aggregation, Factors Influencing Amyloid Fibril Formation, Morphological Features and Types of Aggregated Structures, Each big journey starts with a first step: Importance of Oligomerization, Liquid-Liquid Phase Separation as Triggering Factor of Fibril Formation, and more.
Additional sections cover Experimental Techniques for Detecting and Evaluating the Amyloid Fibrils, Prediction of Protein Aggregation, Amyloid Fibril Cytotoxicity and Associated Disorders, Inhibitors of Amyloid Fibril Formation, Therapeutic Approaches in Proteinopathies, Functional Amyloids, Biotechnological Applications of Amyloid Fibrils, and The Hidden World of Protein Aggregation.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. Chapter One: Protein aggregation: An overview - p. 2 8. Chapter Two: Pathways of amyloid fibril formation and protein aggregation - p. 12 9. Chapter Three: Factors influencing amyloid fibril formation - p. 56 10. Chapter Four: Morphological features and types of aggregated structures - p. 86 11. Chapter Five: Each big journey starts with a first step: Importance of oligomerization - p. 112 12. Chapter Six: Liquid-liquid phase separation as triggering factor of fibril formation - p. 144 13. Chapter Seven: Experimental techniques for detecting and evaluating the amyloid fibrils - p. 185 14. Chapter Eight: Prediction of protein aggregation - p. 230 15. Chapter Nine: Amyloid fibril cytotoxicity and associated disorders - p. 266 16. Chapter Ten: Inhibitors of amyloid fibril formation - p. 292 17. Chapter Eleven: Therapeutic approaches in proteinopathies - p. 342 18. Chapter Twelve: Functional amyloids - p. 390 19. Chapter Thirteen: Biotechnological applications of amyloid fibrils - p. 436 20. Chapter Fourteen: The hidden world of protein aggregation - p. 474 21. Index - p. 494
The Hidden World of Protein Aggregation, Volume 206 provides a comprehensive exploration of protein aggregation, uncovering the factors behind the formation of amorphous aggregates and ordered structures called amyloid fibrils. It delves into the advantages and disadvantages of protein aggregates, addressing topics such as cytotoxicity and disorders linked to misfolding. Specific chapters in this release include Protein Aggregation: An Overview, Pathways of Amyloid Fibril Formation and Aggregation, Factors Influencing Amyloid Fibril Formation, Morphological Features and Types of Aggregated Structures, Each big journey starts with a first step: Importance of Oligomerization, Liquid-Liquid Phase Separation as Triggering Factor of Fibril Formation, and more.
Additional sections cover Experimental Techniques for Detecting and Evaluating the Amyloid Fibrils, Prediction of Protein Aggregation, Amyloid Fibril Cytotoxicity and Associated Disorders, Inhibitors of Amyloid Fibril Formation, Therapeutic Approaches in Proteinopathies, Functional Amyloids, Biotechnological Applications of Amyloid Fibrils, and The Hidden World of Protein Aggregation.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. Chapter One: Protein aggregation: An overview - p. 2 8. Chapter Two: Pathways of amyloid fibril formation and protein aggregation - p. 12 9. Chapter Three: Factors influencing amyloid fibril formation - p. 56 10. Chapter Four: Morphological features and types of aggregated structures - p. 86 11. Chapter Five: Each big journey starts with a first step: Importance of oligomerization - p. 112 12. Chapter Six: Liquid-liquid phase separation as triggering factor of fibril formation - p. 144 13. Chapter Seven: Experimental techniques for detecting and evaluating the amyloid fibrils - p. 185 14. Chapter Eight: Prediction of protein aggregation - p. 230 15. Chapter Nine: Amyloid fibril cytotoxicity and associated disorders - p. 266 16. Chapter Ten: Inhibitors of amyloid fibril formation - p. 292 17. Chapter Eleven: Therapeutic approaches in proteinopathies - p. 342 18. Chapter Twelve: Functional amyloids - p. 390 19. Chapter Thirteen: Biotechnological applications of amyloid fibrils - p. 436 20. Chapter Fourteen: The hidden world of protein aggregation - p. 474 21. Index - p. 494
