The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.
1. I. INTRODUCTION - p. 220 2. II. NUTRIENT REQUIREMENTS - p. 220 3. III. REQUIRED NUTRIENTS - p. 220 4. IV. NATURAL-OCCURRING CONTAMINANTS - p. 264 5. V. DIET RESTRICTION - p. 267 6. VI. CLASSIFICATION AND SELECTION OF DIETS - p. 269 7. VII. DIET STERILIZATION - p. 271 8. VIII. DIET FORMULATION - p. 273 9. IX. DIET MANUFACTURE - p. 274 10. X. PHYSICAL FORMS OF RAT DIETS - p. 274 11. XI. DIET STORAGE - p. 274 12. Chapter 10: Housing and Environment - p. 301 13. Chapter 11: Bacterial, Mycoplasmal and Mycotic Infections - p. 337 14. Publisher Summary - p. 337 15. I. INTRODUCTION - p. 339 16. II. BACTERIAL INFECTIONS - p. 340 17. III. MYCOTIC INFECTIONS - p. 382 18. IV. MYCOPLASMAL AND RICKETTSIAL INFECTIONS - p. 389 19. Chapter 12: Viral Disease - p. 421 20. Chapter 13: Parasitic Diseases - p. 451 21. Chapter 14: Neoplastic Disease - p. 478 22. Chapter 15: Metabolic, Traumatic, and Miscellaneous Diseases - p. 511 23. Publisher Summary - p. 511 24. I. INTRODUCTION - p. 514 25. II. CARDIOVASCULAR SYSTEM - p. 515 26. III. HEMOLYMPHATIC SYSTEM - p. 519 27. IV. RESPIRATORY SYSTEM - p. 520 28. V. GASTROINTESTINAL SYSTEM - p. 522 29. VI. URINARY SYSTEM - p. 525 30. VII. ENDOCRINE SYSTEM - p. 532 31. VIII. NEUROLOGICAL SYSTEM - p. 533 32. IX. OCULAR SYSTEM - p. 534 33. X. MUSCULOSKELETAL SYSTEM - p. 535 34. XI. INTEGUMENTARY SYSTEM - p. 537 35. XII. REPRODUCTIVE SYSTEM - p. 538 36. ACKNOWLEDGMENTS - p. 538 37. Chapter 16: Medical Management and Diagnostic Approaches - p. 546 38. Chapter 17: Occupational Health and Safety - p. 564 39. Chapter 18: Experimental Modeling and Research Methodology - p. 586 40. Chapter 19: Anesthesia and Analgesia - p. 625 41. Publisher Summary - p. 625 42. I. INTRODUCTION - p. 628 43. II. PREOPERATIVE CONSIDERATIONS - p. 628 44. III. PAIN ASSESSMENT AND TREATMENT - p. 635 45. IV. DRUG DOSES AND DOSE PREPARATION - p. 636 46. V. ADMINISTRATION ROUTES AND EQUIPMENT - p. 637 47. VI. INHALATION ANESTHETICS - p. 641 48. VII. PARENTERAL AGENTS - p. 645 49. VIII. SPECIAL ANESTHETIC CONSIDERATIONS - p. 658 50. Chapter 20: Euthanasia and Necropsy - p. 664 51. Chapter 21: Integrating Biology with Rat Genomic Tools - p. 678 52. Chapter 22: Gnotobiotics - p. 692 53. Chapter 23: Spontaneous, Surgically and Chemically Induced Models of Disease - p. 710 54. Chapter 24: The Nude Rat - p. 732 55. Chapter 25: Gerontology and Age-Associated Lesions - p. 759 56. Chapter 26: Cardiovascular Research - p. 772 57. Chapter 27: Toxicology - p. 802 58. Chapter 28: Embryology and Teratology - p. 816 59. Chapter 29: Immunology - p. 846 60. Chapter 30: Wild and Black Rats - p. 864 61. Appendix 1: Selected Normative Data - p. 882 62. Subject Index - p. 884
The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.
1. I. INTRODUCTION - p. 220 2. II. NUTRIENT REQUIREMENTS - p. 220 3. III. REQUIRED NUTRIENTS - p. 220 4. IV. NATURAL-OCCURRING CONTAMINANTS - p. 264 5. V. DIET RESTRICTION - p. 267 6. VI. CLASSIFICATION AND SELECTION OF DIETS - p. 269 7. VII. DIET STERILIZATION - p. 271 8. VIII. DIET FORMULATION - p. 273 9. IX. DIET MANUFACTURE - p. 274 10. X. PHYSICAL FORMS OF RAT DIETS - p. 274 11. XI. DIET STORAGE - p. 274 12. Chapter 10: Housing and Environment - p. 301 13. Chapter 11: Bacterial, Mycoplasmal and Mycotic Infections - p. 337 14. Publisher Summary - p. 337 15. I. INTRODUCTION - p. 339 16. II. BACTERIAL INFECTIONS - p. 340 17. III. MYCOTIC INFECTIONS - p. 382 18. IV. MYCOPLASMAL AND RICKETTSIAL INFECTIONS - p. 389 19. Chapter 12: Viral Disease - p. 421 20. Chapter 13: Parasitic Diseases - p. 451 21. Chapter 14: Neoplastic Disease - p. 478 22. Chapter 15: Metabolic, Traumatic, and Miscellaneous Diseases - p. 511 23. Publisher Summary - p. 511 24. I. INTRODUCTION - p. 514 25. II. CARDIOVASCULAR SYSTEM - p. 515 26. III. HEMOLYMPHATIC SYSTEM - p. 519 27. IV. RESPIRATORY SYSTEM - p. 520 28. V. GASTROINTESTINAL SYSTEM - p. 522 29. VI. URINARY SYSTEM - p. 525 30. VII. ENDOCRINE SYSTEM - p. 532 31. VIII. NEUROLOGICAL SYSTEM - p. 533 32. IX. OCULAR SYSTEM - p. 534 33. X. MUSCULOSKELETAL SYSTEM - p. 535 34. XI. INTEGUMENTARY SYSTEM - p. 537 35. XII. REPRODUCTIVE SYSTEM - p. 538 36. ACKNOWLEDGMENTS - p. 538 37. Chapter 16: Medical Management and Diagnostic Approaches - p. 546 38. Chapter 17: Occupational Health and Safety - p. 564 39. Chapter 18: Experimental Modeling and Research Methodology - p. 586 40. Chapter 19: Anesthesia and Analgesia - p. 625 41. Publisher Summary - p. 625 42. I. INTRODUCTION - p. 628 43. II. PREOPERATIVE CONSIDERATIONS - p. 628 44. III. PAIN ASSESSMENT AND TREATMENT - p. 635 45. IV. DRUG DOSES AND DOSE PREPARATION - p. 636 46. V. ADMINISTRATION ROUTES AND EQUIPMENT - p. 637 47. VI. INHALATION ANESTHETICS - p. 641 48. VII. PARENTERAL AGENTS - p. 645 49. VIII. SPECIAL ANESTHETIC CONSIDERATIONS - p. 658 50. Chapter 20: Euthanasia and Necropsy - p. 664 51. Chapter 21: Integrating Biology with Rat Genomic Tools - p. 678 52. Chapter 22: Gnotobiotics - p. 692 53. Chapter 23: Spontaneous, Surgically and Chemically Induced Models of Disease - p. 710 54. Chapter 24: The Nude Rat - p. 732 55. Chapter 25: Gerontology and Age-Associated Lesions - p. 759 56. Chapter 26: Cardiovascular Research - p. 772 57. Chapter 27: Toxicology - p. 802 58. Chapter 28: Embryology and Teratology - p. 816 59. Chapter 29: Immunology - p. 846 60. Chapter 30: Wild and Black Rats - p. 864 61. Appendix 1: Selected Normative Data - p. 882 62. Subject Index - p. 884