The Lung: Development, Aging and the Environment, Third Edition provides an understanding of the multifaceted nature of lung development, aging and the environment influences of these processes. As an essential resource to respiratory, pulmonary and thoracic scientists and physicians, this book provides an interface between the "normal" and "disease" cluster of chapters, allowing for a natural complement. The interface between different lung diseases affecting the pediatric lung also adds a useful source for comparing how different lung diseases share key pathophysiological features. This same complementarity comes across in the logical line up of chapters dealing with the "normal" pediatric lung.
New research, including cell-based strategies for infant lung function, epigenetics and prenatal environmental exposure (including wildfires) on lung development and function are some of the important additions to this edition of this reference work.
1. Introduction to the Third Edition - p. xvii 2. Part I: Critical events in normal development and aging - p. xvii 3. Chapter 1. Lung progenitor cell specification and morphogenesis - p. 3 4. Chapter 2. Alveolar development - p. 13 5. Chapter 3. Development of the innervation of the lower airways: structure and function - p. 29 6. Chapter 4. Pulmonary vascular development - p. 71 7. Chapter 5. Developmental physiology of the pulmonary circulation - p. 111 8. Chapter 6. Physical, endocrine, and growth factors in lung development - p. 131 9. Chapter 7. The development and function of the pulmonary surfactant system in health, prematurity, and genetic disease - p. 159 10. Chapter 8. Ontogeny of the pulmonary immune system - p. 203 11. Chapter 9. Macrophages and the lung - p. 219 12. Chapter 10. Adaptation to mechanical signals in the lung: Recruitment of reserves, remodeling, and regrowth - p. 229 13. Chapter 11. Pulmonary transition at birth - p. 253 14. Chapter 12. Normal aging of the lung - p. 269 15. Part II: Environmental and disease influences on lung development and aging - p. 290 16. Chapter 13. Epigenetics and the developmental origins of lung disease - p. 295 17. Chapter 14. Pulmonary consequences of preterm birth - p. 309 18. Chapter 15. Preterm birth and the developing lung: Long-term programming effects on respiratory function - p. 329 19. Chapter 16. The effects of neonatal oxygen exposure on lung development - p. 357 20. Chapter 17. Restricted growth during early development: long-term effects on lung structure and function - p. 377 21. Chapter 18. Cell-based strategies for the treatment of injury to the developing lung - p. 403 22. Chapter 19. Effects of environmental tobacco smoke during early life stages - p. 427 23. Chapter 20. Nicotine exposure during early development: Effects on the lung - p. 447 24. Chapter 21. Implications of early life exposures to electronic nicotine delivery system (ENDS) aerosols - p. 461 25. Chapter 22. Exposure to allergens during development - p. 495 26. Chapter 23. Effect of environment on the developing and adult pulmonary surfactant system and in the aging lung - p. 505 27. Chapter 24. Environmental determinants of lung aging - p. 543 28. Chapter 25. The role of epigenetic mechanisms in lung diseases and environmental exposure - p. 577 29. Chapter 26. Dynamic microbiotal changes in the human lung - p. 603 30. Chapter 27. Viral respiratory pathogens and acute lung injury in pregnancy, with a focus on epidemiology and pathophysiology of ARDS amidst the COVID-19 pandemic - p. 615 31. Chapter 28. The lung exposome: Accelerating precision respiratory health - p. 629 32. Index - p. 647
The Lung: Development, Aging and the Environment, Third Edition provides an understanding of the multifaceted nature of lung development, aging and the environment influences of these processes. As an essential resource to respiratory, pulmonary and thoracic scientists and physicians, this book provides an interface between the "normal" and "disease" cluster of chapters, allowing for a natural complement. The interface between different lung diseases affecting the pediatric lung also adds a useful source for comparing how different lung diseases share key pathophysiological features. This same complementarity comes across in the logical line up of chapters dealing with the "normal" pediatric lung.
New research, including cell-based strategies for infant lung function, epigenetics and prenatal environmental exposure (including wildfires) on lung development and function are some of the important additions to this edition of this reference work.
1. Introduction to the Third Edition - p. xvii 2. Part I: Critical events in normal development and aging - p. xvii 3. Chapter 1. Lung progenitor cell specification and morphogenesis - p. 3 4. Chapter 2. Alveolar development - p. 13 5. Chapter 3. Development of the innervation of the lower airways: structure and function - p. 29 6. Chapter 4. Pulmonary vascular development - p. 71 7. Chapter 5. Developmental physiology of the pulmonary circulation - p. 111 8. Chapter 6. Physical, endocrine, and growth factors in lung development - p. 131 9. Chapter 7. The development and function of the pulmonary surfactant system in health, prematurity, and genetic disease - p. 159 10. Chapter 8. Ontogeny of the pulmonary immune system - p. 203 11. Chapter 9. Macrophages and the lung - p. 219 12. Chapter 10. Adaptation to mechanical signals in the lung: Recruitment of reserves, remodeling, and regrowth - p. 229 13. Chapter 11. Pulmonary transition at birth - p. 253 14. Chapter 12. Normal aging of the lung - p. 269 15. Part II: Environmental and disease influences on lung development and aging - p. 290 16. Chapter 13. Epigenetics and the developmental origins of lung disease - p. 295 17. Chapter 14. Pulmonary consequences of preterm birth - p. 309 18. Chapter 15. Preterm birth and the developing lung: Long-term programming effects on respiratory function - p. 329 19. Chapter 16. The effects of neonatal oxygen exposure on lung development - p. 357 20. Chapter 17. Restricted growth during early development: long-term effects on lung structure and function - p. 377 21. Chapter 18. Cell-based strategies for the treatment of injury to the developing lung - p. 403 22. Chapter 19. Effects of environmental tobacco smoke during early life stages - p. 427 23. Chapter 20. Nicotine exposure during early development: Effects on the lung - p. 447 24. Chapter 21. Implications of early life exposures to electronic nicotine delivery system (ENDS) aerosols - p. 461 25. Chapter 22. Exposure to allergens during development - p. 495 26. Chapter 23. Effect of environment on the developing and adult pulmonary surfactant system and in the aging lung - p. 505 27. Chapter 24. Environmental determinants of lung aging - p. 543 28. Chapter 25. The role of epigenetic mechanisms in lung diseases and environmental exposure - p. 577 29. Chapter 26. Dynamic microbiotal changes in the human lung - p. 603 30. Chapter 27. Viral respiratory pathogens and acute lung injury in pregnancy, with a focus on epidemiology and pathophysiology of ARDS amidst the COVID-19 pandemic - p. 615 31. Chapter 28. The lung exposome: Accelerating precision respiratory health - p. 629 32. Index - p. 647
