The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon.
The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research.
1. Introduction - p. xix 2. Part A: The Microbiota of the Gastrointestinal Tract - p. xxii 3. Chapter 1: The Upper Gastrointestinal Tract—Esophagus and Stomach - p. xxii 4. Chapter 2: Characterizing and Functionally Defining the Gut Microbiota: Methodology and Implications - p. 13 5. Chapter 3: Microbiota of the Gastrointestinal Tract in Infancy - p. 25 6. Chapter 4: Identification of the Microbiota in the Aging Process - p. 35 7. Part B: Common Organisms and Probiotics - p. 56 8. Chapter 5: Escherichia coli Nissle 1917 - p. 56 9. Chapter 6: Probiotics of the Acidophilus Group: Lactobacillus acidophilus, delbrueckii subsp. bulgaricus and johnsonii - p. 69 10. Chapter 7: Lactobacillus rhamnosus GG - p. 78 11. Chapter 8: Lactobacillus reuteri - p. 88 12. Chapter 9: The Use of Lactobacillus casei and Lactobacillus paracasei in Clinical Trials for the Improvement of Human Health - p. 97 13. Chapter 10: Beneficial Influences of Lactobacillus plantarum on Human Health and Disease - p. 108 14. Chapter 11: Use of Bacillus in Human Intestinal Probiotic Applications - p. 117 15. Chapter 12: Bifidobacteria as Probiotic Organisms: An Introduction - p. 123 16. Chapter 13: Bifidobacterium animalis spp. lactis - p. 126 17. Chapter 14: Bifidobacterium bifidum - p. 130 18. Chapter 15: Bifidobacterium breve - p. 133 19. Chapter 16: Bifidobacterium longum - p. 137 20. Chapter 17: Bifidobacterium longum spp. infantis - p. 141 21. Chapter 18: Common Organisms and Probiotics: Saccharomyces boulardii - p. 144 22. Chapter 19: Common Organisms and Probiotics: Streptococcus thermophilus (Streptococcus salivarius subsp. thermophilus) - p. 164 23. Chapter 20: Complexities and Pitfalls in the Production of Multispecies Probiotics: The Paradigmatic Case of VSL#3 Formulation and Visbiome - p. 169 24. Chapter 21: The Viruses of the Gut Microbiota - p. 178 25. Part C: Food Substrates Important to the Microbiota - p. 183 26. Chapter 22: Dietary Fiber, Soluble and Insoluble, Carbohydrates, Fructose, and Lipids - p. 183 27. Chapter 23: Prebiotics: Inulin and Other Oligosaccharides - p. 200 28. Chapter 24: The Benefits of Yogurt, Cultures, and Fermentation - p. 208 29. Part D: Basic Physiologic Effects of Microbiota - p. 223 30. Chapter 25: Dysbiosis - p. 223 31. Chapter 26: Immunologic Response in the Host - p. 232 32. Chapter 27: Gastrointestinal Microbiota and the Neural System - p. 241 33. Chapter 28: Effect on the Host Metabolism - p. 247 34. Chapter 29: Relationship Between Gut Microbiota, Energy Metabolism, and Obesity - p. 253 35. Chapter 30: Taxonomic and Metagenomic Alterations of Microbiota in Bariatric Surgery - p. 258 36. Chapter 31: The Influence of Microbiota on Mechanisms of Bariatric Surgery - p. 265 37. Part E: Management of Disease and Disorders by Prebiotics and Probiotic Therapy - p. 281 38. Chapter 32: Allergic and Immunologic Disorders - p. 281 39. Chapter 33: Probiotics Use in Infectious Disease (Respiratory, Diarrhea, and Antibiotic-Associated Diarrhea) - p. 298 40. Chapter 34: FMT in Clostridium difficile and Other Potential Uses - p. 313 41. Chapter 35: Probiotics in the Treatment of Pouchitis - p. 326 42. Chapter 36: Probiotic Treatment in Crohn’s Disease - p. 330 43. Chapter 37: Treatment of Inflammatory Bowel Disease in Ulcerative Colitis - p. 341 44. Chapter 38: Treatment of Functional Bowel Disorders With Prebiotics and Probiotics - p. 354 45. Chapter 39: Celiac Disease, the Microbiome, and Probiotics - p. 364 46. Chapter 40: Probiotics for the Treatment of Liver Disease - p. 371 47. Chapter 41: The Prevention and Treatment of Radiation and Chemotherapy-Induced Intestinal Mucositis - p. 381 48. Chapter 42: The Role of the Brain–Gut–Microbiome in Mental Health and Mental Disorders - p. 387 49. Chapter 43: Management of Disease and Disorders by Prebiotics and Probiotic Therapy: Probiotics in Bacterial Vaginosis - p. 397 50. Index - p. 407
The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon.
The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research.
1. Introduction - p. xix 2. Part A: The Microbiota of the Gastrointestinal Tract - p. xxii 3. Chapter 1: The Upper Gastrointestinal Tract—Esophagus and Stomach - p. xxii 4. Chapter 2: Characterizing and Functionally Defining the Gut Microbiota: Methodology and Implications - p. 13 5. Chapter 3: Microbiota of the Gastrointestinal Tract in Infancy - p. 25 6. Chapter 4: Identification of the Microbiota in the Aging Process - p. 35 7. Part B: Common Organisms and Probiotics - p. 56 8. Chapter 5: Escherichia coli Nissle 1917 - p. 56 9. Chapter 6: Probiotics of the Acidophilus Group: Lactobacillus acidophilus, delbrueckii subsp. bulgaricus and johnsonii - p. 69 10. Chapter 7: Lactobacillus rhamnosus GG - p. 78 11. Chapter 8: Lactobacillus reuteri - p. 88 12. Chapter 9: The Use of Lactobacillus casei and Lactobacillus paracasei in Clinical Trials for the Improvement of Human Health - p. 97 13. Chapter 10: Beneficial Influences of Lactobacillus plantarum on Human Health and Disease - p. 108 14. Chapter 11: Use of Bacillus in Human Intestinal Probiotic Applications - p. 117 15. Chapter 12: Bifidobacteria as Probiotic Organisms: An Introduction - p. 123 16. Chapter 13: Bifidobacterium animalis spp. lactis - p. 126 17. Chapter 14: Bifidobacterium bifidum - p. 130 18. Chapter 15: Bifidobacterium breve - p. 133 19. Chapter 16: Bifidobacterium longum - p. 137 20. Chapter 17: Bifidobacterium longum spp. infantis - p. 141 21. Chapter 18: Common Organisms and Probiotics: Saccharomyces boulardii - p. 144 22. Chapter 19: Common Organisms and Probiotics: Streptococcus thermophilus (Streptococcus salivarius subsp. thermophilus) - p. 164 23. Chapter 20: Complexities and Pitfalls in the Production of Multispecies Probiotics: The Paradigmatic Case of VSL#3 Formulation and Visbiome - p. 169 24. Chapter 21: The Viruses of the Gut Microbiota - p. 178 25. Part C: Food Substrates Important to the Microbiota - p. 183 26. Chapter 22: Dietary Fiber, Soluble and Insoluble, Carbohydrates, Fructose, and Lipids - p. 183 27. Chapter 23: Prebiotics: Inulin and Other Oligosaccharides - p. 200 28. Chapter 24: The Benefits of Yogurt, Cultures, and Fermentation - p. 208 29. Part D: Basic Physiologic Effects of Microbiota - p. 223 30. Chapter 25: Dysbiosis - p. 223 31. Chapter 26: Immunologic Response in the Host - p. 232 32. Chapter 27: Gastrointestinal Microbiota and the Neural System - p. 241 33. Chapter 28: Effect on the Host Metabolism - p. 247 34. Chapter 29: Relationship Between Gut Microbiota, Energy Metabolism, and Obesity - p. 253 35. Chapter 30: Taxonomic and Metagenomic Alterations of Microbiota in Bariatric Surgery - p. 258 36. Chapter 31: The Influence of Microbiota on Mechanisms of Bariatric Surgery - p. 265 37. Part E: Management of Disease and Disorders by Prebiotics and Probiotic Therapy - p. 281 38. Chapter 32: Allergic and Immunologic Disorders - p. 281 39. Chapter 33: Probiotics Use in Infectious Disease (Respiratory, Diarrhea, and Antibiotic-Associated Diarrhea) - p. 298 40. Chapter 34: FMT in Clostridium difficile and Other Potential Uses - p. 313 41. Chapter 35: Probiotics in the Treatment of Pouchitis - p. 326 42. Chapter 36: Probiotic Treatment in Crohn’s Disease - p. 330 43. Chapter 37: Treatment of Inflammatory Bowel Disease in Ulcerative Colitis - p. 341 44. Chapter 38: Treatment of Functional Bowel Disorders With Prebiotics and Probiotics - p. 354 45. Chapter 39: Celiac Disease, the Microbiome, and Probiotics - p. 364 46. Chapter 40: Probiotics for the Treatment of Liver Disease - p. 371 47. Chapter 41: The Prevention and Treatment of Radiation and Chemotherapy-Induced Intestinal Mucositis - p. 381 48. Chapter 42: The Role of the Brain–Gut–Microbiome in Mental Health and Mental Disorders - p. 387 49. Chapter 43: Management of Disease and Disorders by Prebiotics and Probiotic Therapy: Probiotics in Bacterial Vaginosis - p. 397 50. Index - p. 407
