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Descripción

The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions. This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new edition has been extensively revised to reflect new knowledge derived from advances in molecular and cell biology, biochemistry, diagnostics, and therapeutics as they apply to the pituitary gland.

The wide spectrum of clinical disorders emanating from dysfunction of the master gland is described in detail by experts in the field. Fundamental mechanisms underlying disease pathogenesis are presented to provide the reader with an in-depth understanding of mechanisms subserving both normal and disordered pituitary hormone secretion and action.

This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. Chapters provide medical students, clinical and basic endocrinology trainees, endocrinologists, internists, pediatricians, gynecologists, and neurosurgeons with a comprehensive, yet integrated, text devoted to the science and art of pituitary medicine.

  • Brings together pituitary experts from all areas of research and practice who take readers all the way from bench research, to genomic and proteomic analysis, clinical analysis, and new therapeutic approaches to pituitary disorders
  • Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of issues related to normal and diseased pituitary function
  • Provides a common language for endocrinologists, neurosurgeons, OB/GYNs, and endocrine researchers to discuss how the pituitary gland and hormones affect each major organ system

1. Introduction - p. 467 2. Classification - p. 467 3. Epidemiology and Natural History of Prolactinomas - p. 468 4. Pathogenesis - p. 469 5. Clinical Manifestations - p. 477 6. Diagnosis - p. 479 7. Treatment - p. 484 8. Special Situations - p. 499 9. Acknowledgment - p. 503 10. References - p. 503 11. Chapter 17. Cushing Disease - p. 515 12. Abstract - p. 515 13. Introduction - p. 515 14. Pathophysiology - p. 515 15. Epidemiology - p. 515 16. Chronic ACTH and Proopiomelanocortin (POMC) Peptide Oversecretion by the Pituitary - p. 516 17. Pathology of the Adrenal in Cushing Disease - p. 526 18. Other Causes of Cushing’s Syndrome - p. 527 19. Clinical Features - p. 529 20. Diagnosis of Cushing Disease - p. 531 21. Cushing Disease in Children - p. 532 22. Cushing Disease in Pregnant Women - p. 533 23. Long-Term Outcome of Cushing Disease - p. 533 24. Diagnostic Approach - p. 534 25. Imaging Techniques - p. 541 26. Pitfalls in Diagnosis - p. 542 27. Treatment - p. 548 28. Pituitary Surgery and Radiation - p. 549 29. Medical Treatments - p. 551 30. Overall Approach for Treatment - p. 554 31. Future Directions - p. 555 32. Acknowledgments - p. 556 33. References - p. 556 34. Chapter 18. Thyrotrophin-Secreting Pituitary Tumors - p. 573 35. Chapter 19. Nonfunctioning and Gonadotrophin-Secreting Adenomas - p. 589 36. Chapter 20. Atypical Pituitary Adenomas - p. 605 37. Chapter 21. Genetics of Pituitary Tumor Syndromes - p. 619 38. Chapter 22. Nonpituitary Sellar Masses - p. 631 39. Section IV: Pituitary Procedures - p. 639 40. Chapter 23. Pituitary Imaging - p. 645 41. Chapter 24. Pituitary Surgery - p. 671 42. Index - p. 689

Descripcion
Descripción

The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions. This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new edition has been extensively revised to reflect new knowledge derived from advances in molecular and cell biology, biochemistry, diagnostics, and therapeutics as they apply to the pituitary gland.

The wide spectrum of clinical disorders emanating from dysfunction of the master gland is described in detail by experts in the field. Fundamental mechanisms underlying disease pathogenesis are presented to provide the reader with an in-depth understanding of mechanisms subserving both normal and disordered pituitary hormone secretion and action.

This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. Chapters provide medical students, clinical and basic endocrinology trainees, endocrinologists, internists, pediatricians, gynecologists, and neurosurgeons with a comprehensive, yet integrated, text devoted to the science and art of pituitary medicine.

  • Brings together pituitary experts from all areas of research and practice who take readers all the way from bench research, to genomic and proteomic analysis, clinical analysis, and new therapeutic approaches to pituitary disorders
  • Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of issues related to normal and diseased pituitary function
  • Provides a common language for endocrinologists, neurosurgeons, OB/GYNs, and endocrine researchers to discuss how the pituitary gland and hormones affect each major organ system

1. Introduction - p. 467 2. Classification - p. 467 3. Epidemiology and Natural History of Prolactinomas - p. 468 4. Pathogenesis - p. 469 5. Clinical Manifestations - p. 477 6. Diagnosis - p. 479 7. Treatment - p. 484 8. Special Situations - p. 499 9. Acknowledgment - p. 503 10. References - p. 503 11. Chapter 17. Cushing Disease - p. 515 12. Abstract - p. 515 13. Introduction - p. 515 14. Pathophysiology - p. 515 15. Epidemiology - p. 515 16. Chronic ACTH and Proopiomelanocortin (POMC) Peptide Oversecretion by the Pituitary - p. 516 17. Pathology of the Adrenal in Cushing Disease - p. 526 18. Other Causes of Cushing’s Syndrome - p. 527 19. Clinical Features - p. 529 20. Diagnosis of Cushing Disease - p. 531 21. Cushing Disease in Children - p. 532 22. Cushing Disease in Pregnant Women - p. 533 23. Long-Term Outcome of Cushing Disease - p. 533 24. Diagnostic Approach - p. 534 25. Imaging Techniques - p. 541 26. Pitfalls in Diagnosis - p. 542 27. Treatment - p. 548 28. Pituitary Surgery and Radiation - p. 549 29. Medical Treatments - p. 551 30. Overall Approach for Treatment - p. 554 31. Future Directions - p. 555 32. Acknowledgments - p. 556 33. References - p. 556 34. Chapter 18. Thyrotrophin-Secreting Pituitary Tumors - p. 573 35. Chapter 19. Nonfunctioning and Gonadotrophin-Secreting Adenomas - p. 589 36. Chapter 20. Atypical Pituitary Adenomas - p. 605 37. Chapter 21. Genetics of Pituitary Tumor Syndromes - p. 619 38. Chapter 22. Nonpituitary Sellar Masses - p. 631 39. Section IV: Pituitary Procedures - p. 639 40. Chapter 23. Pituitary Imaging - p. 645 41. Chapter 24. Pituitary Surgery - p. 671 42. Index - p. 689

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