Therapeutic Applications of Nitric Oxide in Cancer and Inflammatory Disorders: Third International Conference on Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated information on the chemistry, signaling of newly derived therapeutic nitric oxide donors/inhibitors, and their complexes in liposomes or nanospheres in both preclinical and clinical investigations.
This book consists of the following: The program and abstracts presented at the Third International Conference in Udine, Italy, September 3-5, 2023; Parts I–V review on (I) the general properties of nitric oxide in diseases; (II) the role of nitric oxide in cancer; (III) nitric oxide and immunity; (IV) nitric oxide and aging; and (V) nitric oxide and therapeutics. In addition, part VI is an educational review on artificial intelligence and its application in diseases. These updated reviews present many examples of research investigations related to the application of novel therapeutic compounds on nitric oxide and new derivatives, as well as their significant therapeutic activities against various resistant cancers that are unresponsive to current treatments and in different inflammatory disorders.
This book is a valuable resource for cancer researchers, oncologists, graduate students, and investigators from medical and biomedical fields who want to learn more about NO and its therapeutic applications in cancer and inflammatory diseases. This book is also highly useful for both clinicians and oncologists as well as pharmaceutical companies involved in the development of new anticancer/antiinflammatory agents.
1. Therapeutic Applications of Nitric Oxide in Cancer and Inflammatory Disorders - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Contributors - p. Page iv 7. About the editors - p. Page v 8. Preface - p. Page vii 9. UDINE 2023 Third International Conference - p. Page x 10. Objective of this volume - p. Page lxxxi 11. Highlights - p. Page lxxxii 12. List of Illustrations - p. Page lxxxiii 13. List of Tables - p. Page lxxxiv 14. Chapter 1 : Nitric oxide pathophysiology and applications in patients undergoing major cardiac surgery - p. Page lxxxiv 15. Chapter 2 : The emerging role of dimethylarginine dimethylaminohydrolase 2 in regulating vasculogenic mimicry in cancer - p. Page 12 16. Chapter 3 : Decoding S-nitrosylation: Theoretical aspects and analytical approaches - p. Page 27 17. Chapter 4 : Preclinical models to assess the pharmacological properties of NO derivatives - p. Page 52 18. Chapter 5 : Nitric oxide-mediated neuroinflammatory pathways as treatment targets in neurodegeneration - p. Page 73 19. Chapter 6 : The role of nitric oxide in gemcitabine resistance of pancreatic cancer cells - p. Page 89 20. Chapter 7 : Exploring the dual role of nitric oxide in glioblastoma - p. Page 112 21. Chapter 8 : Nitric oxide donating systems and their potential in shaping tumor immunoregulation - p. Page 131 22. Chapter 9 : Control of nitric oxide synthase 2: Role of NRF2-regulated distal enhancer - p. Page 154 23. Chapter 10 : Nitric oxide in tumor biology: From stemness to metabolic reprogramming - p. Page 174 24. Chapter 11 : Impact of nitric oxide on hemeprotein maturation and its relevance to cancer and pulmonary diseases - p. Page 190 25. Chapter 12 : Using artificial intelligence to discover new cancer therapies - p. Page 210 26. Index - p. Page 250
Therapeutic Applications of Nitric Oxide in Cancer and Inflammatory Disorders: Third International Conference on Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated information on the chemistry, signaling of newly derived therapeutic nitric oxide donors/inhibitors, and their complexes in liposomes or nanospheres in both preclinical and clinical investigations.
This book consists of the following: The program and abstracts presented at the Third International Conference in Udine, Italy, September 3-5, 2023; Parts I–V review on (I) the general properties of nitric oxide in diseases; (II) the role of nitric oxide in cancer; (III) nitric oxide and immunity; (IV) nitric oxide and aging; and (V) nitric oxide and therapeutics. In addition, part VI is an educational review on artificial intelligence and its application in diseases. These updated reviews present many examples of research investigations related to the application of novel therapeutic compounds on nitric oxide and new derivatives, as well as their significant therapeutic activities against various resistant cancers that are unresponsive to current treatments and in different inflammatory disorders.
This book is a valuable resource for cancer researchers, oncologists, graduate students, and investigators from medical and biomedical fields who want to learn more about NO and its therapeutic applications in cancer and inflammatory diseases. This book is also highly useful for both clinicians and oncologists as well as pharmaceutical companies involved in the development of new anticancer/antiinflammatory agents.
1. Therapeutic Applications of Nitric Oxide in Cancer and Inflammatory Disorders - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Contributors - p. Page iv 7. About the editors - p. Page v 8. Preface - p. Page vii 9. UDINE 2023 Third International Conference - p. Page x 10. Objective of this volume - p. Page lxxxi 11. Highlights - p. Page lxxxii 12. List of Illustrations - p. Page lxxxiii 13. List of Tables - p. Page lxxxiv 14. Chapter 1 : Nitric oxide pathophysiology and applications in patients undergoing major cardiac surgery - p. Page lxxxiv 15. Chapter 2 : The emerging role of dimethylarginine dimethylaminohydrolase 2 in regulating vasculogenic mimicry in cancer - p. Page 12 16. Chapter 3 : Decoding S-nitrosylation: Theoretical aspects and analytical approaches - p. Page 27 17. Chapter 4 : Preclinical models to assess the pharmacological properties of NO derivatives - p. Page 52 18. Chapter 5 : Nitric oxide-mediated neuroinflammatory pathways as treatment targets in neurodegeneration - p. Page 73 19. Chapter 6 : The role of nitric oxide in gemcitabine resistance of pancreatic cancer cells - p. Page 89 20. Chapter 7 : Exploring the dual role of nitric oxide in glioblastoma - p. Page 112 21. Chapter 8 : Nitric oxide donating systems and their potential in shaping tumor immunoregulation - p. Page 131 22. Chapter 9 : Control of nitric oxide synthase 2: Role of NRF2-regulated distal enhancer - p. Page 154 23. Chapter 10 : Nitric oxide in tumor biology: From stemness to metabolic reprogramming - p. Page 174 24. Chapter 11 : Impact of nitric oxide on hemeprotein maturation and its relevance to cancer and pulmonary diseases - p. Page 190 25. Chapter 12 : Using artificial intelligence to discover new cancer therapies - p. Page 210 26. Index - p. Page 250
