Therapeutic Drug Monitoring Data: A Concise Guide, Fourth Edition serves as a ready resource of information on commonly monitored drugs that will help readers make decisions relating to the monitoring and interpretation of results. It is an easy-to-read source of information on intended use, pharmacokinetics, therapeutic range, and toxic concentrations, as well as bioavailability, disposition, metabolism and the excretion of commonly monitored therapeutic drugs. This fully updated fourth edition includes sections on new anticonvulsants, anti-depressant and anti-HIV drugs, new drugs for advanced cancer treatment, and thoroughly updated chapters that address new pitfalls and problems in the lab.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Preface - p. xi 6. Chapter 1: Pharmacokinetics and therapeutic drug monitoring - p. xi 7. Chapter 2: Before and after: The pre-analytical and post-analytical phases of TDM - p. 17 8. Chapter 3: Clinical utility of monitoring free drug levels - p. 25 9. Chapter 4: Effects of bilirubin, lipemia, hemolysis, paraproteins and heterophilic antibodies on immunoassays for therapeutic drug monitoring - p. 42 10. Chapter 5: Application of chromatographic techniques for therapeutic drug monitoring - p. 52 11. Chapter 6: Drug–herb and drug–food interactions and effects on therapeutic drug monitoring - p. 63 12. Chapter 7: Pharmacogenomics and therapeutic drugs monitoring: Are they complementary? - p. 78 13. Chapter 8: Therapeutic drug monitoring using alternative specimens - p. 90 14. Chapter 9: Antiepileptic drugs - p. 98 15. Chapter 10: Therapeutic drug monitoring of antimicrobial, antifungal and antiviral agents - p. 158 16. Chapter 11: Therapeutic drug monitoring of antidepressants and psychoactive drugs - p. 197 17. Chapter 12: Therapeutic drug monitoring of cardioactive drugs - p. 227 18. Chapter 13: Immunosuppressants - p. 270 19. Chapter 14: Analgesics - p. 307 20. Chapter 15: Antineoplastic drugs - p. 330 21. Chapter 16: Caffeine and theophylline - p. 350 22. Index - p. 361
Therapeutic Drug Monitoring Data: A Concise Guide, Fourth Edition serves as a ready resource of information on commonly monitored drugs that will help readers make decisions relating to the monitoring and interpretation of results. It is an easy-to-read source of information on intended use, pharmacokinetics, therapeutic range, and toxic concentrations, as well as bioavailability, disposition, metabolism and the excretion of commonly monitored therapeutic drugs. This fully updated fourth edition includes sections on new anticonvulsants, anti-depressant and anti-HIV drugs, new drugs for advanced cancer treatment, and thoroughly updated chapters that address new pitfalls and problems in the lab.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Preface - p. xi 6. Chapter 1: Pharmacokinetics and therapeutic drug monitoring - p. xi 7. Chapter 2: Before and after: The pre-analytical and post-analytical phases of TDM - p. 17 8. Chapter 3: Clinical utility of monitoring free drug levels - p. 25 9. Chapter 4: Effects of bilirubin, lipemia, hemolysis, paraproteins and heterophilic antibodies on immunoassays for therapeutic drug monitoring - p. 42 10. Chapter 5: Application of chromatographic techniques for therapeutic drug monitoring - p. 52 11. Chapter 6: Drug–herb and drug–food interactions and effects on therapeutic drug monitoring - p. 63 12. Chapter 7: Pharmacogenomics and therapeutic drugs monitoring: Are they complementary? - p. 78 13. Chapter 8: Therapeutic drug monitoring using alternative specimens - p. 90 14. Chapter 9: Antiepileptic drugs - p. 98 15. Chapter 10: Therapeutic drug monitoring of antimicrobial, antifungal and antiviral agents - p. 158 16. Chapter 11: Therapeutic drug monitoring of antidepressants and psychoactive drugs - p. 197 17. Chapter 12: Therapeutic drug monitoring of cardioactive drugs - p. 227 18. Chapter 13: Immunosuppressants - p. 270 19. Chapter 14: Analgesics - p. 307 20. Chapter 15: Antineoplastic drugs - p. 330 21. Chapter 16: Caffeine and theophylline - p. 350 22. Index - p. 361
