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Get the foundational knowledge you need to successfully work in a real-world, clinical lab with Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 8th Edition. From highly respected clinical chemistry expert Nader Rifai, this condensed, easier-to-understand version of the acclaimed Tietz Textbook of Clinical Chemistry and Molecular Diagnostics uses a laboratory perspective to guide you through selecting and performing diagnostic lab tests and accurately evaluating the results. Coverage includes laboratory principles, analytical techniques, instrumentation, analytes, pathophysiology, and more. This eighth edition features new clinical cases from The Coakley Collection, new questions from The Deacon’s Challenge of Biochemical Calculations Collection, plus new content throughout the text to ensure you stay ahead of all the latest techniques, instrumentation, and technologies.

  • Condensed version of the clinical chemistry "bible" offers the same authoritative and well-presented content in a much more focused and streamlined manner.
  • Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing.
  • Updated chapters on molecular diagnostics cover the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field.
  • Learning objectives, key words, and review questions are included in each chapter to support learning.
  • More than 500 illustrations plus easy-to-read tables help readers better understand and remember key concepts.
  • NEW! Clinical Cases from The Coakley Collection use real-life scenarios to demonstrate how concepts from the text will come in to play in real life practice.
  • NEW! Questions from The Deacon’s Challenge of Biochemical Calculations Collection help reinforce concepts and help readers’ critical thinking skills.
  • NEW! Updated content throughout the text keeps readers up to date on the latest techniques, instrumentation, and technologies.
  • NEW! New lead author Nader Rifai lends his expertise as the Director of Clinical Chemistry at Children’s Hospital in Boston, the Editor-in-Chief of the journal Clinical Chemistry, and a Professor of Pathology at Harvard University.

1. Instructions for online access - p. 1066 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Associate Editors - p. v 7. Contributors - p. vii 8. Preface - p. xiii 9. Part I. Principles of Laboratory Medicine - p. xiii 10. 1. Clinical Chemistry and Molecular Diagnostics - p. 1 11. 2. Analytical and Clinical Evaluation of Methods - p. 7 12. 3. Preanalytical Variation - p. 38 13. 4. Biological Variation - p. 51 14. 5. Establishment and Use of Reference Values - p. 64 15. 6. Specimen Collection, Processing, and Other Preanalytical Variables - p. 77 16. 7. Quality Management - p. 90 17. 8. Principles of Basic Techniques and Laboratory Safety - p. 108 18. Part II. Analytical Techniques and Instrumentation - p. 126 19. 9. Optical Techniques - p. 127 20. 10. Electrochemistry and Chemical Sensors - p. 145 21. 11. Electrophoresis - p. 167 22. 12. Chromatography - p. 180 23. 13. Mass Spectrometry - p. 201 24. 14. Enzyme and Rate Analyses - p. 215 25. 15. Immunochemical Techniques - p. 236 26. 16. Automation - p. 251 27. 17. Point-of-Care Testing - p. 273 28. Part III. Analytes - p. 287 29. 18. Amino Acids, Peptides, and Proteins - p. 288 30. 19. Serum Enzymes - p. 313 31. 20. Tumor Markers - p. 331 32. 21. Kidney Function Tests - p. 359 33. 22. Carbohydrates - p. 377 34. 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors - p. 391 35. 24. Electrolytes and Blood Gases - p. 419 36. 25. Hormones - p. 440 37. 26. Catecholamines and Serotonin - p. 450 38. 27. Vitamins and Trace Elements - p. 466 39. 28. Hemoglobin, Iron, and Bilirubin - p. 499 40. 29. Porphyrins and Porphyrias - p. 524 41. 30. Therapeutic Drug Monitoring - p. 541 42. 31. Clinical Toxicology - p. 562 43. 32. Toxic Elements - p. 590 44. Part IV. Pathophysiology - p. 602 45. 33. Diabetes Mellitus - p. 603 46. 34. Cardiovascular Disease - p. 629 47. 35. Kidney Disease - p. 651 48. 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism - p. 679 49. 37. Liver Disease - p. 699 50. 38. Gastric, Pancreatic, and Intestinal Function - p. 723 51. 39. Bone and Mineral Metabolism - p. 744 52. 40. Disorders of the Pituitary Gland - p. 773 53. 41. Adrenal Cortex - p. 787 54. 42. Thyroid Disorders - p. 811 55. 43. Reproduction-Related Disorders - p. 834 56. 44. Pregnancy and Prenatal Testing - p. 861 57. 45. Newborn Screening and Inborn Errors of Metabolism - p. 882 58. 46. Pharmacogenetics - p. 898 59. Part V. Molecular Diagnostics - p. 913 60. 47. Molecular Principles - p. 914 61. 48. Molecular Techniques - p. 936 62. 49. Molecular Applications - p. 961 63. Appendix. Reference Information for the Clinical Laboratory - p. 988 64. Index - p. 1029 65. IUPAC Periodic Table of the Elements - p. 1066

Descripcion
Descripción

Get the foundational knowledge you need to successfully work in a real-world, clinical lab with Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 8th Edition. From highly respected clinical chemistry expert Nader Rifai, this condensed, easier-to-understand version of the acclaimed Tietz Textbook of Clinical Chemistry and Molecular Diagnostics uses a laboratory perspective to guide you through selecting and performing diagnostic lab tests and accurately evaluating the results. Coverage includes laboratory principles, analytical techniques, instrumentation, analytes, pathophysiology, and more. This eighth edition features new clinical cases from The Coakley Collection, new questions from The Deacon’s Challenge of Biochemical Calculations Collection, plus new content throughout the text to ensure you stay ahead of all the latest techniques, instrumentation, and technologies.

  • Condensed version of the clinical chemistry "bible" offers the same authoritative and well-presented content in a much more focused and streamlined manner.
  • Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing.
  • Updated chapters on molecular diagnostics cover the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field.
  • Learning objectives, key words, and review questions are included in each chapter to support learning.
  • More than 500 illustrations plus easy-to-read tables help readers better understand and remember key concepts.
  • NEW! Clinical Cases from The Coakley Collection use real-life scenarios to demonstrate how concepts from the text will come in to play in real life practice.
  • NEW! Questions from The Deacon’s Challenge of Biochemical Calculations Collection help reinforce concepts and help readers’ critical thinking skills.
  • NEW! Updated content throughout the text keeps readers up to date on the latest techniques, instrumentation, and technologies.
  • NEW! New lead author Nader Rifai lends his expertise as the Director of Clinical Chemistry at Children’s Hospital in Boston, the Editor-in-Chief of the journal Clinical Chemistry, and a Professor of Pathology at Harvard University.

1. Instructions for online access - p. 1066 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Associate Editors - p. v 7. Contributors - p. vii 8. Preface - p. xiii 9. Part I. Principles of Laboratory Medicine - p. xiii 10. 1. Clinical Chemistry and Molecular Diagnostics - p. 1 11. 2. Analytical and Clinical Evaluation of Methods - p. 7 12. 3. Preanalytical Variation - p. 38 13. 4. Biological Variation - p. 51 14. 5. Establishment and Use of Reference Values - p. 64 15. 6. Specimen Collection, Processing, and Other Preanalytical Variables - p. 77 16. 7. Quality Management - p. 90 17. 8. Principles of Basic Techniques and Laboratory Safety - p. 108 18. Part II. Analytical Techniques and Instrumentation - p. 126 19. 9. Optical Techniques - p. 127 20. 10. Electrochemistry and Chemical Sensors - p. 145 21. 11. Electrophoresis - p. 167 22. 12. Chromatography - p. 180 23. 13. Mass Spectrometry - p. 201 24. 14. Enzyme and Rate Analyses - p. 215 25. 15. Immunochemical Techniques - p. 236 26. 16. Automation - p. 251 27. 17. Point-of-Care Testing - p. 273 28. Part III. Analytes - p. 287 29. 18. Amino Acids, Peptides, and Proteins - p. 288 30. 19. Serum Enzymes - p. 313 31. 20. Tumor Markers - p. 331 32. 21. Kidney Function Tests - p. 359 33. 22. Carbohydrates - p. 377 34. 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors - p. 391 35. 24. Electrolytes and Blood Gases - p. 419 36. 25. Hormones - p. 440 37. 26. Catecholamines and Serotonin - p. 450 38. 27. Vitamins and Trace Elements - p. 466 39. 28. Hemoglobin, Iron, and Bilirubin - p. 499 40. 29. Porphyrins and Porphyrias - p. 524 41. 30. Therapeutic Drug Monitoring - p. 541 42. 31. Clinical Toxicology - p. 562 43. 32. Toxic Elements - p. 590 44. Part IV. Pathophysiology - p. 602 45. 33. Diabetes Mellitus - p. 603 46. 34. Cardiovascular Disease - p. 629 47. 35. Kidney Disease - p. 651 48. 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism - p. 679 49. 37. Liver Disease - p. 699 50. 38. Gastric, Pancreatic, and Intestinal Function - p. 723 51. 39. Bone and Mineral Metabolism - p. 744 52. 40. Disorders of the Pituitary Gland - p. 773 53. 41. Adrenal Cortex - p. 787 54. 42. Thyroid Disorders - p. 811 55. 43. Reproduction-Related Disorders - p. 834 56. 44. Pregnancy and Prenatal Testing - p. 861 57. 45. Newborn Screening and Inborn Errors of Metabolism - p. 882 58. 46. Pharmacogenetics - p. 898 59. Part V. Molecular Diagnostics - p. 913 60. 47. Molecular Principles - p. 914 61. 48. Molecular Techniques - p. 936 62. 49. Molecular Applications - p. 961 63. Appendix. Reference Information for the Clinical Laboratory - p. 988 64. Index - p. 1029 65. IUPAC Periodic Table of the Elements - p. 1066

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