Transglutaminase: Fundamentals and Applications, a new volume in the Foundations and Frontiers in Enzymology series, stands as a comprehensive resource on this increasingly important class of enzymes. Following an introduction to the field from the Editors, international experts discuss basic biology and structure – function relationships of transglutaminases, ongoing fundamental research, as well as new application areas, including food processing, material synthesis, biomedicine and disease treatment, and biotechnology. Approaches for sourcing transglutaminases from animals, plants, and microorganisms are considered in-depth, followed by chapters on applied uses in biomedicine, skin and bone biology and medicine, drug development, tissue engineering, seafood bioprocessing, dairy bioprocessing, synthesis of materials and polymers, and as an immobilization agent. Research protocols are also provided, including research rationale, design, substrates, assays and microassay steps for studying transglutaminases.
1. An introduction to transglutaminases - p. Page v 2. List of Illustrations - p. Page xiv 3. List of Tables - p. Page xv 4. 1 : Transglutaminases from microorganisms - p. Page xv 5. 2 : Transglutaminases from plant sources - p. Page 16 6. 3 : Transglutaminases from animals - p. Page 31 7. 4 : Newly engineered transglutaminases - p. Page 57 8. 5 : Transglutaminase 2 in neurological conditions - p. Page 94 9. 6 : Transglutaminases in cardiovascular health and disease - p. Page 122 10. 7 : Microbial transglutaminase in drug development - p. Page 156 11. 8 : Transglutaminases in meat and seafood bioprocessing - p. Page 177 12. 9 : Transglutaminase in dairy processing - p. Page 195 13. 10 : Transglutaminase in noodles, pastas, and baked products - p. Page 233 14. 11 : Transglutaminase in textile, wool, silk, and leather processing - p. Page 264 15. 12 : Immobilization of transglutaminases and transglutaminase as immobilization agent - p. Page 289 16. 13 : Industrial production of transglutaminase - p. Page 316 17. Index - p. Page 345
Transglutaminase: Fundamentals and Applications, a new volume in the Foundations and Frontiers in Enzymology series, stands as a comprehensive resource on this increasingly important class of enzymes. Following an introduction to the field from the Editors, international experts discuss basic biology and structure – function relationships of transglutaminases, ongoing fundamental research, as well as new application areas, including food processing, material synthesis, biomedicine and disease treatment, and biotechnology. Approaches for sourcing transglutaminases from animals, plants, and microorganisms are considered in-depth, followed by chapters on applied uses in biomedicine, skin and bone biology and medicine, drug development, tissue engineering, seafood bioprocessing, dairy bioprocessing, synthesis of materials and polymers, and as an immobilization agent. Research protocols are also provided, including research rationale, design, substrates, assays and microassay steps for studying transglutaminases.
1. An introduction to transglutaminases - p. Page v 2. List of Illustrations - p. Page xiv 3. List of Tables - p. Page xv 4. 1 : Transglutaminases from microorganisms - p. Page xv 5. 2 : Transglutaminases from plant sources - p. Page 16 6. 3 : Transglutaminases from animals - p. Page 31 7. 4 : Newly engineered transglutaminases - p. Page 57 8. 5 : Transglutaminase 2 in neurological conditions - p. Page 94 9. 6 : Transglutaminases in cardiovascular health and disease - p. Page 122 10. 7 : Microbial transglutaminase in drug development - p. Page 156 11. 8 : Transglutaminases in meat and seafood bioprocessing - p. Page 177 12. 9 : Transglutaminase in dairy processing - p. Page 195 13. 10 : Transglutaminase in noodles, pastas, and baked products - p. Page 233 14. 11 : Transglutaminase in textile, wool, silk, and leather processing - p. Page 264 15. 12 : Immobilization of transglutaminases and transglutaminase as immobilization agent - p. Page 289 16. 13 : Industrial production of transglutaminase - p. Page 316 17. Index - p. Page 345