Tumor Microenvironment Regulation of Tumor Expansion is a practical guide to understand and perform research on tumor microenvironments, and to support related clinical decisions.
Tumor progression is linked to an imbalance between positive and negative regulators, and mainly depends on the release of specific growth factors by inflammatory or neoplastic cells. Inflammatory infiltrate contributes to tumor progression and the metastatic process, and there are many reports of associations between tumor inflammatory infiltrate, progression, and prognosis. Understanding different contexts of organs is a key factor in improving treatment outcome, especially in new therapeutic treatments targeting components of the tumor microenvironment.
This book is a valuable resource for cancer researchers, clinicians, graduate students, and scientists in many biomedical fields who are interested in the complex relationship between the tumor microenvironment and its context in specific organs.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Preface - p. ix 7. Chapter 1. Tumor microenvironment - p. 1 8. Chapter 2. Bone marrow niches - p. 11 9. Chapter 3. Metastatic cascade - p. 21 10. Chapter 4. Epithelial mesenchymal transition - p. 33 11. Chapter 5. The extracellular matrix - p. 41 12. Chapter 6. Tumor blood vessels and tumor endothelial cells - p. 51 13. Chapter 7. Tumor basement membrane - p. 61 14. Chapter 8. Tumor pericytes - p. 65 15. Chapter 9. Inflammatory cells in tumor microenvironment - p. 75 16. Chapter 10. Other cells of the tumor microenvironment - p. 113 17. Chapter 11. Therapeutic strategies - p. 139 18. Index - p. 155
Tumor Microenvironment Regulation of Tumor Expansion is a practical guide to understand and perform research on tumor microenvironments, and to support related clinical decisions.
Tumor progression is linked to an imbalance between positive and negative regulators, and mainly depends on the release of specific growth factors by inflammatory or neoplastic cells. Inflammatory infiltrate contributes to tumor progression and the metastatic process, and there are many reports of associations between tumor inflammatory infiltrate, progression, and prognosis. Understanding different contexts of organs is a key factor in improving treatment outcome, especially in new therapeutic treatments targeting components of the tumor microenvironment.
This book is a valuable resource for cancer researchers, clinicians, graduate students, and scientists in many biomedical fields who are interested in the complex relationship between the tumor microenvironment and its context in specific organs.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Preface - p. ix 7. Chapter 1. Tumor microenvironment - p. 1 8. Chapter 2. Bone marrow niches - p. 11 9. Chapter 3. Metastatic cascade - p. 21 10. Chapter 4. Epithelial mesenchymal transition - p. 33 11. Chapter 5. The extracellular matrix - p. 41 12. Chapter 6. Tumor blood vessels and tumor endothelial cells - p. 51 13. Chapter 7. Tumor basement membrane - p. 61 14. Chapter 8. Tumor pericytes - p. 65 15. Chapter 9. Inflammatory cells in tumor microenvironment - p. 75 16. Chapter 10. Other cells of the tumor microenvironment - p. 113 17. Chapter 11. Therapeutic strategies - p. 139 18. Index - p. 155
