Upconversion Nanoparticles for Biomedical Applications provides a comprehensive overview of the chemistry, properties, characterization, and emerging applications of lanthanide-doped upconversion nanoparticles (UCNPs), focusing on upconversion mechanisms, fluorescent properties, and biomedical applications. The emerging applications of UCNPs include cancer diagnostics and therapy, biosensing and bioassays, bioimaging, drug and gene delivery, cellular optogenetics, and the detection of small biomolecules and ions. The biocompatibility, biodegradability, bio-distribution, toxicity and regulatory considerations of upconversion are fully considered.
This book offers a unique reference resource for researchers, bringing together a global authorship to cover the fundamentals, state-of-the-art, current challenges, and future perspectives of upconversion nanoparticles.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xi 7. Preface - p. xv 8. 1. Upconversion nanoparticles: current research trends and future perspectives - p. 1 9. 2. Synthesis methods of upconversion nanoparticles: design architecture and upconversion mechanism - p. 45 10. 3. Surface engineering, bioconjugation, colloidal stability and fluorescent characteristics of upconversion nanoparticles - p. 89 11. 4. Physicochemical characterizations of upconversion nanoparticles - p. 133 12. 5. Photon-avalanching nanoparticles for biomedical applications - p. 185 13. 6. Upconversion nanoparticles for cancer diagnostics and therapy - p. 227 14. 7. Upconversion nanoparticles for mechanical force sensing and thermometry - p. 269 15. 8. Upconversion nanoparticles for biosensing and bioassays - p. 341 16. 9. Upconversion nanoparticles for bioimaging applications - p. 411 17. 10. Upconversion nanoparticles for biological superresolution imaging - p. 463 18. 11. Upconversion nanoparticles for drug and gene delivery - p. 517 19. 12. Upconversion nanoparticles in cellular optogenetics - p. 577 20. 13. Upconversion nanoparticles for detection of small biomolecules and ions - p. 623 21. 14. Nanocomposites, nanohybrids and heterostructures of upconversion nanoparticles for biomedical applications - p. 681 22. 15. Biocompatibility, biodegradability, bio-distribution, toxicity, and regulatory challenges of upconversion nanoparticles in the medical field - p. 731 23. 16. Future perspectives of upconversion nanoparticles in biomedical and clinical settings for diagnostics and therapeutic applications - p. 775 24. Index - p. 815
Upconversion Nanoparticles for Biomedical Applications provides a comprehensive overview of the chemistry, properties, characterization, and emerging applications of lanthanide-doped upconversion nanoparticles (UCNPs), focusing on upconversion mechanisms, fluorescent properties, and biomedical applications. The emerging applications of UCNPs include cancer diagnostics and therapy, biosensing and bioassays, bioimaging, drug and gene delivery, cellular optogenetics, and the detection of small biomolecules and ions. The biocompatibility, biodegradability, bio-distribution, toxicity and regulatory considerations of upconversion are fully considered.
This book offers a unique reference resource for researchers, bringing together a global authorship to cover the fundamentals, state-of-the-art, current challenges, and future perspectives of upconversion nanoparticles.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xi 7. Preface - p. xv 8. 1. Upconversion nanoparticles: current research trends and future perspectives - p. 1 9. 2. Synthesis methods of upconversion nanoparticles: design architecture and upconversion mechanism - p. 45 10. 3. Surface engineering, bioconjugation, colloidal stability and fluorescent characteristics of upconversion nanoparticles - p. 89 11. 4. Physicochemical characterizations of upconversion nanoparticles - p. 133 12. 5. Photon-avalanching nanoparticles for biomedical applications - p. 185 13. 6. Upconversion nanoparticles for cancer diagnostics and therapy - p. 227 14. 7. Upconversion nanoparticles for mechanical force sensing and thermometry - p. 269 15. 8. Upconversion nanoparticles for biosensing and bioassays - p. 341 16. 9. Upconversion nanoparticles for bioimaging applications - p. 411 17. 10. Upconversion nanoparticles for biological superresolution imaging - p. 463 18. 11. Upconversion nanoparticles for drug and gene delivery - p. 517 19. 12. Upconversion nanoparticles in cellular optogenetics - p. 577 20. 13. Upconversion nanoparticles for detection of small biomolecules and ions - p. 623 21. 14. Nanocomposites, nanohybrids and heterostructures of upconversion nanoparticles for biomedical applications - p. 681 22. 15. Biocompatibility, biodegradability, bio-distribution, toxicity, and regulatory challenges of upconversion nanoparticles in the medical field - p. 731 23. 16. Future perspectives of upconversion nanoparticles in biomedical and clinical settings for diagnostics and therapeutic applications - p. 775 24. Index - p. 815
