Zika Virus Biology, Transmission, and Pathways: The Neuroscience of Zika, Volume One provides a detailed introduction to the molecular biology of the Zika virus and its features, transmission, and impact on neurological systems. Designed to better readers’ understanding of the Zika virus, this volume features chapters on the immune response, molecular mechanisms, and other areas to better understand underlying pathways. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions.
1. Zika Virus Biology, Transmission, and Pathways - p. i 2. Cover - p. i 3. Title Page - p. ii 4. Copyright - p. iv 5. Table of Contents - p. iv 6. Dedication - p. v 7. Contributors - p. xix 8. Foreword - p. xxv 9. Preface - p. xxvii 10. Chapter 1 Flaviviruses and where the Zika virus fits in: An overview - p. 5 11. Chapter 2 The innate immune response during Zika virus infection - p. 19 12. Chapter 3 The public health perspective of Zika virus infection - p. 31 13. Chapter 4 Inequality in Zika virus and congenital Zika syndrome - p. 43 14. Chapter 5 Lifestyle factors and congenital Zika syndrome: Drugs, alcohol, and beyond - p. 55 15. Chapter 6 Economic impact of Zika virus infection and associated conditions - p. 63 16. Chapter 7 Health promotion, health education, and risk communication for Zika virus disease - p. 75 17. Chapter 8 Molecular mechanisms of Zika virus-induced neurological pathology - p. 83 18. Chapter 9 Validation of Zika virus infections: Nonmolecular aspects, immunoassays, and beyond - p. 95 19. Chapter 10 Validation of Zika virus infections: A focus on molecular methods - p. 107 20. Chapter 11 Coinfection of Zika with Dengue and Chikungunya virus - p. 119 21. Chapter 12 Zika virus, pathology, and control: Zika vaccine strategies in development - p. 129 22. Chapter 13 The adult brain and neurologic manifestations of the Zika virus - p. 145 23. Chapter 14 Postmortem studies: Contribution to understand the pathogenesis of congenital Zika syndrome - p. 155 24. Chapter 15 Developmental trajectories in infants and toddlers born with congenital Zika syndrome - p. 169 25. Chapter 16 Host genetic susceptibility to ZIKV congenital syndrome: A tale of twins - p. 179 26. Chapter 17 Zika virus infection disrupts development of both neurons and glial cells - p. 189 27. Chapter 18 Neurological manifestations similar to multiple sclerosis in adults after Zika virus infection - p. 199 28. Chapter 19 Zika virus and the blood-brain barrier - p. 209 29. Chapter 20 Systems immunology of flavivirus infection - p. 221 30. Chapter 21 Genetic susceptibility to congenital Zika syndrome: Current research and future perspectives - p. 235 31. Chapter 22 Hearing and Zika virus infection - p. 245 32. Chapter 23 Neuromyelitis optica spectrum disorder: What it is and how it relates to Zika virus - p. 255 33. Chapter 24 Zika virus infection and cytokines - p. 267 34. Chapter 25 Urological sequels in the scope of the Congenital Zika Syndrome - p. 279 35. Chapter 26 Zika virus and impact on male fertility - p. 289 36. Chapter 27 Testicular cell types and infection by Zika virus - p. 299 37. Chapter 28 Proteome alterations promoted by Zika virus infection - p. 307 38. Chapter 29 SOMAscan proteomics of Zika-infected cells - p. 319 39. Chapter 30 Zika virus as an oncolytic therapy against brain tumors - p. 327 40. Chapter 31 Zika virus in Brazil - p. 341 41. Chapter 32 Zika virus and the Middle East - p. 351 42. Chapter 33 Genetic diversity of Zika virus in Thailand: How does this compare with other countries - p. 359 43. Chapter 34 Zika virus in Vietnam: Biology, transmission, pathology, associated conditions, and controls - p. 367 44. Chapter 35 Zika virus in Vietnam: Epidemic, distribution, strain origin, and potential risks for community health - p. 377 45. Chapter 36 Zika virus infection in Mexico: Epidemiological and clinical data - p. 387 46. Chapter 37 Cytopathicity and pathogenesis of Zika virus strains - p. 397 47. Chapter 38 Molecular evolution and codon usage bias of Zika virus - p. 409 48. Chapter 39 Endosomal compartmentation and the transport route of Zika virus - p. 419 49. Chapter 40 Location of virus antigens in murine tissues infected with Zika virus - p. 431 50. Chapter 41 The role of seminal Zika viral shedding: Tropism, duration, and magnitude - p. 443 51. Chapter 42 Nonhuman occurrence of Zika virus infection: Implications for control - p. 453 52. Zika virus intrusion into the blood supply: Concerns about transfusion safety - p. 467 53. Chapter 44 Research and recommended resources on Zika virus, pathology, and control - p. 479 54. Index - p. 493
Zika Virus Biology, Transmission, and Pathways: The Neuroscience of Zika, Volume One provides a detailed introduction to the molecular biology of the Zika virus and its features, transmission, and impact on neurological systems. Designed to better readers’ understanding of the Zika virus, this volume features chapters on the immune response, molecular mechanisms, and other areas to better understand underlying pathways. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions.
1. Zika Virus Biology, Transmission, and Pathways - p. i 2. Cover - p. i 3. Title Page - p. ii 4. Copyright - p. iv 5. Table of Contents - p. iv 6. Dedication - p. v 7. Contributors - p. xix 8. Foreword - p. xxv 9. Preface - p. xxvii 10. Chapter 1 Flaviviruses and where the Zika virus fits in: An overview - p. 5 11. Chapter 2 The innate immune response during Zika virus infection - p. 19 12. Chapter 3 The public health perspective of Zika virus infection - p. 31 13. Chapter 4 Inequality in Zika virus and congenital Zika syndrome - p. 43 14. Chapter 5 Lifestyle factors and congenital Zika syndrome: Drugs, alcohol, and beyond - p. 55 15. Chapter 6 Economic impact of Zika virus infection and associated conditions - p. 63 16. Chapter 7 Health promotion, health education, and risk communication for Zika virus disease - p. 75 17. Chapter 8 Molecular mechanisms of Zika virus-induced neurological pathology - p. 83 18. Chapter 9 Validation of Zika virus infections: Nonmolecular aspects, immunoassays, and beyond - p. 95 19. Chapter 10 Validation of Zika virus infections: A focus on molecular methods - p. 107 20. Chapter 11 Coinfection of Zika with Dengue and Chikungunya virus - p. 119 21. Chapter 12 Zika virus, pathology, and control: Zika vaccine strategies in development - p. 129 22. Chapter 13 The adult brain and neurologic manifestations of the Zika virus - p. 145 23. Chapter 14 Postmortem studies: Contribution to understand the pathogenesis of congenital Zika syndrome - p. 155 24. Chapter 15 Developmental trajectories in infants and toddlers born with congenital Zika syndrome - p. 169 25. Chapter 16 Host genetic susceptibility to ZIKV congenital syndrome: A tale of twins - p. 179 26. Chapter 17 Zika virus infection disrupts development of both neurons and glial cells - p. 189 27. Chapter 18 Neurological manifestations similar to multiple sclerosis in adults after Zika virus infection - p. 199 28. Chapter 19 Zika virus and the blood-brain barrier - p. 209 29. Chapter 20 Systems immunology of flavivirus infection - p. 221 30. Chapter 21 Genetic susceptibility to congenital Zika syndrome: Current research and future perspectives - p. 235 31. Chapter 22 Hearing and Zika virus infection - p. 245 32. Chapter 23 Neuromyelitis optica spectrum disorder: What it is and how it relates to Zika virus - p. 255 33. Chapter 24 Zika virus infection and cytokines - p. 267 34. Chapter 25 Urological sequels in the scope of the Congenital Zika Syndrome - p. 279 35. Chapter 26 Zika virus and impact on male fertility - p. 289 36. Chapter 27 Testicular cell types and infection by Zika virus - p. 299 37. Chapter 28 Proteome alterations promoted by Zika virus infection - p. 307 38. Chapter 29 SOMAscan proteomics of Zika-infected cells - p. 319 39. Chapter 30 Zika virus as an oncolytic therapy against brain tumors - p. 327 40. Chapter 31 Zika virus in Brazil - p. 341 41. Chapter 32 Zika virus and the Middle East - p. 351 42. Chapter 33 Genetic diversity of Zika virus in Thailand: How does this compare with other countries - p. 359 43. Chapter 34 Zika virus in Vietnam: Biology, transmission, pathology, associated conditions, and controls - p. 367 44. Chapter 35 Zika virus in Vietnam: Epidemic, distribution, strain origin, and potential risks for community health - p. 377 45. Chapter 36 Zika virus infection in Mexico: Epidemiological and clinical data - p. 387 46. Chapter 37 Cytopathicity and pathogenesis of Zika virus strains - p. 397 47. Chapter 38 Molecular evolution and codon usage bias of Zika virus - p. 409 48. Chapter 39 Endosomal compartmentation and the transport route of Zika virus - p. 419 49. Chapter 40 Location of virus antigens in murine tissues infected with Zika virus - p. 431 50. Chapter 41 The role of seminal Zika viral shedding: Tropism, duration, and magnitude - p. 443 51. Chapter 42 Nonhuman occurrence of Zika virus infection: Implications for control - p. 453 52. Zika virus intrusion into the blood supply: Concerns about transfusion safety - p. 467 53. Chapter 44 Research and recommended resources on Zika virus, pathology, and control - p. 479 54. Index - p. 493
