Zika Virus Impact, Diagnosis, Control, and Models: Volume Two: The Neuroscience of Zika examines diagnosis, vaccines, and potential therapy methods for Zika virus syndrome. The book also details the neuroscience of Guillain-Barré syndrome, its effects and neuromuscular rehabilitation. It is designed to help readers better understand detection, therapies for Zika virus, preventative vaccines, diagnosis and associated microcephaly. Chapters on models enable further research and understanding. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions.
1. Zika Virus Impact, Diagnosis, Control, and Models - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Dedication - p. Page v 7. Contributors - p. Page v 8. Foreword - p. Page xi 9. Preface - p. Page xii 10. List of Illustrations - p. Page xiii 11. List of Tables - p. Page xiv 12. Chapter 1 : How Zika virus emerged and spread worldwide - p. Page xiv 13. Chapter 2 : Clinical neurological spectrum of adult and congenital ZIKV infection: An overview of virology, pathogenesis, and management - p. Page 9 14. Chapter 3 : Classification of Zika virus sequences with respect to their species and subspecies - p. Page 23 15. Chapter 4 : Health knowledge about Zika virus: Brazil aspects - p. Page 35 16. Chapter 5 : Zika virus infection and replication organelle biogenesis - p. Page 46 17. Chapter 6 : Microcephaly: Zika and other congenital infections - p. Page 55 18. Chapter 7 : Zika and impact on the nervous system in children - p. Page 69 19. Chapter 8 : Use of induced pluripotent stem cells and cerebral organoids to profile Zika virus infection: Features and findings - p. Page 80 20. Chapter 9 : Zika, miRNAs, and microcephaly genes - p. Page 93 21. Chapter 10 : Adherens junctions and cell polarity: What they are and how they relate to congenital Zika virus syndrome - p. Page 106 22. Chapter 11 : Severe Guillain-Barré syndrome - p. Page 118 23. Chapter 12 : Oxidative stress in Guillain-Barré syndrome and linkage with neurology - p. Page 131 24. Chapter 13 : Neuromuscular effects and rehabilitation in Guillain-Barré syndrome - p. Page 141 25. Chapter 14 : Postinfectious demyelinating diseases: Guillain-Barré syndrome and beyond - p. Page 145 26. Chapter 15 : Linking in placental alterations, Zika virus, and Guillain-Barré syndrome - p. Page 159 27. Chapter 16 : Case study: Neuroimaging of adults and Zika virus - p. Page 173 28. Chapter 17 : Case study: Magnetic resonance imaging and babies with Zika virus infection - p. Page 181 29. Chapter 18 : A case study of Guillain-Barre syndrome associated with Zika virus infection - p. Page 191 30. Chapter 19 : Clinical manifestations and outcomes of Guillain-Barre syndrome complicating Zika virus infection - p. Page 196 31. Chapter 20 : Auditory brainstem in Zika virus: Insights about brain development in microcephaly - p. Page 203 32. Chapter 21 : Magnetic resonance imaging use in detecting neurological abnormalities in Zika virus infection - p. Page 210 33. Chapter 22 : Magnetic modulation biosensing: How it works and how it can be used to detect the Zika virus - p. Page 228 34. Chapter 23 : RNA extraction techniques of different body fluids for Zika virus: Blood, genitourinary specimens, saliva, and other relevant fluids - p. Page 237 35. Chapter 24 : Saliva and urine analysis of Zika virus using loop-mediated isothermal amplification (LAMP) - p. Page 250 36. Chapter 25 : Graphene-based biosensors for the detection of Zika virus - p. Page 258 37. Chapter 26 : The ZIKV Detect IgM Capture ELISA - p. Page 270 38. Chapter 27 : Quantum dot-based fluoroassays for Zika - p. Page 278 39. Chapter 28 : Serological detection of specific IgA antibodies against Zika virus nonstructural protein 1 contributes to diagnosis of acute Zika virus infections - p. Page 288 40. Chapter 29 : Serological algorithms: How they can be used for differentiating ZIKV from DENV infection - p. Page 299 41. Chapter 30 : Aedes aegypti and the use of natural molecules for its control: Implications in the decrease of Zika disease - p. Page 307 42. Chapter 31 : Strategies of Zika virus control with larvicides and their toxic potential: A focus on pyriproxyfen - p. Page 323 43. Chapter 32 : Larvicides: Plant oils and Zika control - p. Page 333 44. Chapter 33 : Pyridobenzothiazolones as anti-flavivirus agents: Impact on Zika virus - p. Page 342 45. Chapter 34 : The development of human monoclonal antibodies against Zika virus - p. Page 356 46. Chapter 35 : The Zika virus NS1 protein as a vaccine target - p. Page 364 47. Chapter 36 : Zika vaccines must prevent sexual transmission - p. Page 370 48. Chapter 37 : Nucleoside analogue inhibitors for Zika virus infection - p. Page 381 49. Chapter 38 : Medicinal plants as promising source of natural antiviral substances against Zika virus - p. Page 391 50. Chapter 39 : Protein kinase C as a target in the control of viruses and implication for Zika virus - p. Page 404 51. Chapter 40 : Nanotechnology applied in the control and diagnosis of Zika virus and its vectors - p. Page 411 52. Chapter 41 : Neonatal microcephaly and humanized mouse models for Zika viral pathogenesis and immunity - p. Page 422 53. Chapter 42 : Use of liver cells to discover novel peptides for anti-Zika strategies - p. Page 433 54. Chapter 43 : In vivo mouse models to investigate the microcephaly associated with Zika virus - p. Page 446 55. Chapter 44 : Zika virus infection with primates: Fetal outcomes - p. Page 456 56. Index - p. Page 469
Zika Virus Impact, Diagnosis, Control, and Models: Volume Two: The Neuroscience of Zika examines diagnosis, vaccines, and potential therapy methods for Zika virus syndrome. The book also details the neuroscience of Guillain-Barré syndrome, its effects and neuromuscular rehabilitation. It is designed to help readers better understand detection, therapies for Zika virus, preventative vaccines, diagnosis and associated microcephaly. Chapters on models enable further research and understanding. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions.
1. Zika Virus Impact, Diagnosis, Control, and Models - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Dedication - p. Page v 7. Contributors - p. Page v 8. Foreword - p. Page xi 9. Preface - p. Page xii 10. List of Illustrations - p. Page xiii 11. List of Tables - p. Page xiv 12. Chapter 1 : How Zika virus emerged and spread worldwide - p. Page xiv 13. Chapter 2 : Clinical neurological spectrum of adult and congenital ZIKV infection: An overview of virology, pathogenesis, and management - p. Page 9 14. Chapter 3 : Classification of Zika virus sequences with respect to their species and subspecies - p. Page 23 15. Chapter 4 : Health knowledge about Zika virus: Brazil aspects - p. Page 35 16. Chapter 5 : Zika virus infection and replication organelle biogenesis - p. Page 46 17. Chapter 6 : Microcephaly: Zika and other congenital infections - p. Page 55 18. Chapter 7 : Zika and impact on the nervous system in children - p. Page 69 19. Chapter 8 : Use of induced pluripotent stem cells and cerebral organoids to profile Zika virus infection: Features and findings - p. Page 80 20. Chapter 9 : Zika, miRNAs, and microcephaly genes - p. Page 93 21. Chapter 10 : Adherens junctions and cell polarity: What they are and how they relate to congenital Zika virus syndrome - p. Page 106 22. Chapter 11 : Severe Guillain-Barré syndrome - p. Page 118 23. Chapter 12 : Oxidative stress in Guillain-Barré syndrome and linkage with neurology - p. Page 131 24. Chapter 13 : Neuromuscular effects and rehabilitation in Guillain-Barré syndrome - p. Page 141 25. Chapter 14 : Postinfectious demyelinating diseases: Guillain-Barré syndrome and beyond - p. Page 145 26. Chapter 15 : Linking in placental alterations, Zika virus, and Guillain-Barré syndrome - p. Page 159 27. Chapter 16 : Case study: Neuroimaging of adults and Zika virus - p. Page 173 28. Chapter 17 : Case study: Magnetic resonance imaging and babies with Zika virus infection - p. Page 181 29. Chapter 18 : A case study of Guillain-Barre syndrome associated with Zika virus infection - p. Page 191 30. Chapter 19 : Clinical manifestations and outcomes of Guillain-Barre syndrome complicating Zika virus infection - p. Page 196 31. Chapter 20 : Auditory brainstem in Zika virus: Insights about brain development in microcephaly - p. Page 203 32. Chapter 21 : Magnetic resonance imaging use in detecting neurological abnormalities in Zika virus infection - p. Page 210 33. Chapter 22 : Magnetic modulation biosensing: How it works and how it can be used to detect the Zika virus - p. Page 228 34. Chapter 23 : RNA extraction techniques of different body fluids for Zika virus: Blood, genitourinary specimens, saliva, and other relevant fluids - p. Page 237 35. Chapter 24 : Saliva and urine analysis of Zika virus using loop-mediated isothermal amplification (LAMP) - p. Page 250 36. Chapter 25 : Graphene-based biosensors for the detection of Zika virus - p. Page 258 37. Chapter 26 : The ZIKV Detect IgM Capture ELISA - p. Page 270 38. Chapter 27 : Quantum dot-based fluoroassays for Zika - p. Page 278 39. Chapter 28 : Serological detection of specific IgA antibodies against Zika virus nonstructural protein 1 contributes to diagnosis of acute Zika virus infections - p. Page 288 40. Chapter 29 : Serological algorithms: How they can be used for differentiating ZIKV from DENV infection - p. Page 299 41. Chapter 30 : Aedes aegypti and the use of natural molecules for its control: Implications in the decrease of Zika disease - p. Page 307 42. Chapter 31 : Strategies of Zika virus control with larvicides and their toxic potential: A focus on pyriproxyfen - p. Page 323 43. Chapter 32 : Larvicides: Plant oils and Zika control - p. Page 333 44. Chapter 33 : Pyridobenzothiazolones as anti-flavivirus agents: Impact on Zika virus - p. Page 342 45. Chapter 34 : The development of human monoclonal antibodies against Zika virus - p. Page 356 46. Chapter 35 : The Zika virus NS1 protein as a vaccine target - p. Page 364 47. Chapter 36 : Zika vaccines must prevent sexual transmission - p. Page 370 48. Chapter 37 : Nucleoside analogue inhibitors for Zika virus infection - p. Page 381 49. Chapter 38 : Medicinal plants as promising source of natural antiviral substances against Zika virus - p. Page 391 50. Chapter 39 : Protein kinase C as a target in the control of viruses and implication for Zika virus - p. Page 404 51. Chapter 40 : Nanotechnology applied in the control and diagnosis of Zika virus and its vectors - p. Page 411 52. Chapter 41 : Neonatal microcephaly and humanized mouse models for Zika viral pathogenesis and immunity - p. Page 422 53. Chapter 42 : Use of liver cells to discover novel peptides for anti-Zika strategies - p. Page 433 54. Chapter 43 : In vivo mouse models to investigate the microcephaly associated with Zika virus - p. Page 446 55. Chapter 44 : Zika virus infection with primates: Fetal outcomes - p. Page 456 56. Index - p. Page 469
