Adrenal disorders are often difficult to diagnose due to common symptoms, and challenging to treat due to common comorbidities. Adrenal Disorders: 100 Cases from the Adrenal Clinic provides a comprehensive, case-based approach to the evaluation and treatment of both common and uncommon adrenal disorders, offering practical, real-world guidance highlighted by ultrasound scans, biopsy images, and tables.
Features 100 two-page cases covering a wide range of common and uncommon adrenal disorders.
Includes case report, investigations, treatment, and outcome for each case, plus a case overview with expert advice, take-home points, and references.
Organizes comprehensive content by type of disorder, including adrenal masses (benign and malignant), primary aldosteronism, ACTH-independent Cushing syndrome, ACTH-dependent Cushing syndrome, adrenal carcinoma, and pheochromocytoma.
1. Cover Image - p. C 2. Title Page - p. i 3. Copyright - p. ii 4. Dedication - p. iii 5. Preface - p. iv 6. Acknowledgments - p. v 7. About the Authors - p. vi 8. Contents - p. vii 9. Section A Incidentally DiscoveredAdrenal Mass - p. 1 10. Case 1 45-Year-Old Woman With an Incidentally Discovered Large Adrenal Mass - p. 5 11. Case 2 Adrenal Mass in a Patient With History of Extraadrenal Malignancy: The Role of Imaging - p. 8 12. Case 3 Incidentally Discovered Adrenal Mass in a Patient With History of Extraadrenal Malignancy: The Role of Adrenal Biopsy - p. 12 13. Case 4 Nonfunctioning Lipid Rich Adrenocortical Adenoma: Role of Follow-Up - p. 15 14. Case 5 54-Year-Old Woman With an Incidentally Discovered Adrenal Mass and Abnormal Dexamethasone Suppression Test: Role of Adrenalectomy - p. 18 15. Case 6 Lipid-Poor Adrenal Masses: The Case for Aggressive Management - p. 21 16. Section B Primary Aldosteronism - p. 25 17. Case 7 Primary Aldosteronism: When Adrenal Venous Sampling Is Not Needed Before Unilateral Adrenalectomy - p. 28 18. Case 8 Primary Aldosteronism With Unilateral Adrenal Nodule on Computed Tomography - p. 31 19. Case 9 Primary Aldosteronism With Bilateral Adrenal Nodules on Computed Tomography - p. 34 20. Case 10 Primary Aldosteronism Caused by Unilateral Adrenal Hyperplasia - p. 38 21. Case 11 Primary Aldosteronism in a Patient With Bilateral Macronodular Adrenal Hyperplasia and Associated Clinically Important Cortisol Cosecretion - p. 42 22. Case 12 Primary Aldosteronism in a Patient With an Adrenal Macroadenoma and Clinically Important Cortisol Cosecretion - p. 45 23. Case 13 Primary Aldosteronism in a Patient Treated With Spironolactone - p. 48 24. Case 14 Failed Catheterization of the Right Adrenal Vein: When Incomplete Adrenal Venous Sampling Data Can Be Used to Direct a Surgical Cure - p. 51 25. Case 15 Primary Aldosteronism: When Adrenal Venous Sampling Shows Suppressed Aldosterone Secretion From Both Adrenal Glands - p. 54 26. Section C Corticotropin-Independent Cushing Syndrome - p. 59 27. Case 16 28-Year-Old Woman With Remote History of Adrenal Mass Presenting With New-Onset Hypertension and Weight Gain - p. 62 28. Case 17 26-Year-Old Woman With a Discrepant Workup for Cushing Syndrome Subtype - p. 66 29. Case 18 45-Year-Old Woman With Corticotropin-Independent Cushing Syndrome and Bilateral Adrenal Adenomas - p. 68 30. Case 19 Corticotropin-Independent Cushing Syndrome in a Patient With “Normal” Adrenal Imaging - p. 71 31. Case 20 66-Year-Old Woman With Corticotropin-Independent Hypercortisolism and Bilateral Macronodular Adrenal Hyperplasia - p. 74 32. Case 21 35-Year-Old Woman With Low Bone Density and Fractures - p. 77 33. Case 22 Carney Triad (Pentad) and Adrenal Adenoma With Clinically Important Cortisol Secretory Autonomy - p. 80 34. Section D Adrenal Cortical Carcinoma and Oncocytic Neoplasm - p. 85 35. Case 23 Adrenal Cortical Carcinoma in a Patient With a History of Adrenal Incidentaloma - p. 88 36. Case 24 Unexpected Diagnosis of Adrenal Cortical Carcinoma: Role of Urinary Steroid Profiling - p. 91 37. Case 25 Oncocytic Adrenocortical Carcinoma - p. 94 38. Case 26 Mitotane Therapy in the ENSAT Stage II Adrenocortical Carcinoma - p. 97 39. Case 27 Cortisol-Secreting Metastatic Adrenocortical Carcinoma: Role for Surgical Debulking of the Primary Tumor - p. 100 40. Case 28 Adrenocortical Carcinoma and Severe Cushing Syndrome - p. 103 41. Case 29 Pure Aldosterone-Secreting Adrenocortical Carcinoma - p. 106 42. Case 30 Long-Standing Primary Aldosteronism in a Patient Diagnosed With Metastatic Adrenocortical Carcinoma - p. 109 43. Case 31 Adrenocortical Carcinoma Associated With Lynch Syndrome - p. 112 44. Case 32 Adrenocortical Carcinoma Associated With Multiple Endocrine Neoplasia Type 1 - p. 115 45. Case 33 Adrenocortical Carcinoma Presenting With Inferior Vena Cava Thrombus - p. 118 46. Case 34 Management of Mitotane Therapy in Adrenocortical Carcinoma - p. 121 47. Section E Pheochromocytoma and Paraganglioma - p. 127 48. Case 35 Most Pheochromocytomas Grow Slowly - p. 132 49. Case 36 The “Prebiochemical” Pheochromocytoma - p. 135 50. Case 37 Huge Catecholamine-Secreting Tumor - p. 138 51. Case 38 Metyrosine Use in a Patient With Metastatic Pheochromocytoma - p. 141 52. Case 39 Pheochromocytoma in a Patient With Neurofibromatosis Type 1 - p. 144 53. Case 40 New Diagnosis of Multiple Endocrine Neoplasia Type 2A in a Patient With Bilateral Pheochromocytomas - p. 147 54. Case 41 Pheochromocytoma in a Patient With von Hippel Lindau Disease - p. 150 55. Case 42 Bilateral Pheochromocytoma in a Patient With MYC-Associated Protein X (MAX) Genetic Predisposition - p. 153 56. Case 43 The Cystic Pheochromocytoma - p. 156 57. Case 44 Skull Base and Neck Paragangliomas: Considerations for the Endocrinologist - p. 159 58. Case 45 Cardiac Paraganglioma - p. 162 59. Case 46 Pheochromocytoma in Multiple Endocrine Neoplasia Type 2B - p. 165 60. Case 47 Metastatic Paraganglioma: An Approach to Management and the Use of Serial Imaging to Assess the Rate of Tumor Progression - p. 168 61. Case 48 Metastatic Pheochromocytoma: Role for Ga-68 DOTATATE PET-CT - p. 172 62. Case 49 Carney Triad (Pentad) and Catecholamine-Secreting Paragangliomas - p. 176 63. Case 50 Metastatic Paraganglioma: Role for Systemic Chemotherapy - p. 180 64. Case 51 Cryoablation Therapy for Metastatic Paraganglioma - p. 183 65. Case 52 Paraganglioma in a Patient With Cyanotic Cardiac Disease - p. 186 66. Case 53 Metastatic Paraganglioma—Role for External Beam Radiation Therapy - p. 189 67. Section F Corticotropin-Dependent Hypercortisolism - p. 193 68. Case 54 Corticotropin-Dependent Cushing Syndrome Can Be Frequently Misdiagnosed - p. 197 69. Case 55 Corticotropin-Dependent Cushing Syndrome: Role for Inferior Petrosal Sinus Sampling - p. 201 70. Case 56 Corticotropin-Dependent Cushing Syndrome: When Inferior Petrosal Sinus Sampling Is Not Needed - p. 205 71. Case 57 Severe Corticotropin-Dependent Cushing Syndrome From a Pituitary Adenoma - p. 209 72. Case 58 Ectopic Cushing Syndrome Associated With Multiple Endocrine Neoplasia Type 2B - p. 213 73. Case 59 Ectopic Cushing Syndrome Treated With Cryoablation - p. 215 74. Case 60 Cyclical Ectopic Cushing Syndrome - p. 218 75. Case 61 Mild Cushing Syndrome Associated With Ectopic Corticotropin Secretion - p. 221 76. Case 62 Bilateral Adrenal Cryoablation in Corticotropin-Dependent Cushing Syndrome - p. 224 77. Case 63 Cushing Syndrome Associated With Ectopic Corticotropin and Corticotropin-Releasing Hormone–Secreting Pheochromocytoma - p. 227 78. Case 64 Cushing Syndrome in the Setting of Multiple Endocrine Neoplasia Type 1 - p. 231 79. Section G Other Adrenal Masses - p. 235 80. Case 65 Adrenal Myelolipoma: A Computed Tomography Diagnosis - p. 236 81. Case 66 Adrenal Schwannoma - p. 238 82. Case 67 Trauma-Related Unilateral Adrenal Hemorrhage - p. 241 83. Case 68 Bilateral Adrenal Hemorrhage - p. 244 84. Case 69 Primary Adrenal Teratoma - p. 247 85. Case 70 The Adrenal Stone - p. 250 86. Case 71 Simple Adrenal Cyst - p. 253 87. Case 72 Adrenal Cystic Lymphangioma - p. 255 88. Case 73 Adrenal Hemangioma - p. 257 89. Case 74 Adrenal Ganglioneuroma - p. 259 90. Case 75 42-Year-Old Woman With a Large Composite Adrenal Mass - p. 262 91. Case 76 Primary Adrenal Leiomyosarcoma - p. 265 92. Case 77 Primary Adrenal Lymphoma - p. 268 93. Case 78 39-Year-Old Man With a Large Adrenal Mass - p. 272 94. Case 79 59-Year-Old Man With Enlarging Bilateral Adrenal Masses - p. 274 95. Case 80 65-Year-Old Man With Primary Adrenal Insufficiency - p. 277 96. Case 81 47-Year-Old Man With Primary Adrenal Insufficiency - p. 280 97. Case 82 Bilateral Adrenal Myelolipoma: Think of Congenital Adrenal Hyperplasia - p. 282 98. Case 83 A Unilateral Lipid-Poor Adrenal Mass: An Atypical Presentation of Adrenal Histoplasmosis - p. 285 99. Case 84 Bilateral Macronodular Adrenal Hyperplasia in the Setting of Multiple Endocrine Neoplasia Type 1 - p. 289 100. Case 85 Pseudo-Adrenal Masses - p. 292 101. Section H Adrenal and Ovarian Hyperandrogenism - p. 297 102. Case 86 A Huge Adrenal Myelolipoma in a Patient With a Suboptimally Controlled Congenital Adrenal Hyperplasia - p. 299 103. Case 87 Balancing Glucocorticoid and Androgen Excess in Congenital Adrenal Hyperplasia - p. 302 104. Case 88 Dehydroepiandrosterone Sulfate: The “Love It” or “Hate It” Hormone - p. 305 105. Case 89 Sorting Out the Source of Androgen Excess in a Postmenopausal Woman With an Adrenal and an Ovarian Mass - p. 308 106. Case 90 Primary Testosterone-Secreting Adrenocortical Carcinoma in a Premenopausal Woman - p. 311 107. Case 91 Premenopausal Woman With Testosterone-Secreting Ovarian Tumor - p. 314 108. Case 92 Sorting Out the Source of Androgen Excess in a Postmenopausal Woman With an Adrenal Mass - p. 317 109. Case 93 Testosterone-Secreting Benign Adrenal Adenoma in a Postmenopausal Woman - p. 320 110. Section I Adrenal Disorders in Pregnancy - p. 323 111. Case 94 Malignant Pheochromocytoma in Pregnancy - p. 324 112. Case 95 Catecholamine-Secreting Paraganglioma in Pregnancy - p. 329 113. Case 96 The Peripartum Diagnosis of Pheochromocytoma and a Genetic Mystery Solved - p. 333 114. Case 97 History of Pregnancy in a 41-Year-Old Woman With Undiagnosed Cushing Syndrome - p. 338 115. Case 98 Pregnancy in a Patient With Primary Adrenal Insufficiency - p. 341 116. Case 99 Pregnancy in a Patient With 21-Hydroxylase Deficiency - p. 343 117. Case 100 Primary Aldosteronism in Pregnancy - p. 345 118. Index - p. 349
Adrenal disorders are often difficult to diagnose due to common symptoms, and challenging to treat due to common comorbidities. Adrenal Disorders: 100 Cases from the Adrenal Clinic provides a comprehensive, case-based approach to the evaluation and treatment of both common and uncommon adrenal disorders, offering practical, real-world guidance highlighted by ultrasound scans, biopsy images, and tables.
Features 100 two-page cases covering a wide range of common and uncommon adrenal disorders.
Includes case report, investigations, treatment, and outcome for each case, plus a case overview with expert advice, take-home points, and references.
Organizes comprehensive content by type of disorder, including adrenal masses (benign and malignant), primary aldosteronism, ACTH-independent Cushing syndrome, ACTH-dependent Cushing syndrome, adrenal carcinoma, and pheochromocytoma.
1. Cover Image - p. C 2. Title Page - p. i 3. Copyright - p. ii 4. Dedication - p. iii 5. Preface - p. iv 6. Acknowledgments - p. v 7. About the Authors - p. vi 8. Contents - p. vii 9. Section A Incidentally DiscoveredAdrenal Mass - p. 1 10. Case 1 45-Year-Old Woman With an Incidentally Discovered Large Adrenal Mass - p. 5 11. Case 2 Adrenal Mass in a Patient With History of Extraadrenal Malignancy: The Role of Imaging - p. 8 12. Case 3 Incidentally Discovered Adrenal Mass in a Patient With History of Extraadrenal Malignancy: The Role of Adrenal Biopsy - p. 12 13. Case 4 Nonfunctioning Lipid Rich Adrenocortical Adenoma: Role of Follow-Up - p. 15 14. Case 5 54-Year-Old Woman With an Incidentally Discovered Adrenal Mass and Abnormal Dexamethasone Suppression Test: Role of Adrenalectomy - p. 18 15. Case 6 Lipid-Poor Adrenal Masses: The Case for Aggressive Management - p. 21 16. Section B Primary Aldosteronism - p. 25 17. Case 7 Primary Aldosteronism: When Adrenal Venous Sampling Is Not Needed Before Unilateral Adrenalectomy - p. 28 18. Case 8 Primary Aldosteronism With Unilateral Adrenal Nodule on Computed Tomography - p. 31 19. Case 9 Primary Aldosteronism With Bilateral Adrenal Nodules on Computed Tomography - p. 34 20. Case 10 Primary Aldosteronism Caused by Unilateral Adrenal Hyperplasia - p. 38 21. Case 11 Primary Aldosteronism in a Patient With Bilateral Macronodular Adrenal Hyperplasia and Associated Clinically Important Cortisol Cosecretion - p. 42 22. Case 12 Primary Aldosteronism in a Patient With an Adrenal Macroadenoma and Clinically Important Cortisol Cosecretion - p. 45 23. Case 13 Primary Aldosteronism in a Patient Treated With Spironolactone - p. 48 24. Case 14 Failed Catheterization of the Right Adrenal Vein: When Incomplete Adrenal Venous Sampling Data Can Be Used to Direct a Surgical Cure - p. 51 25. Case 15 Primary Aldosteronism: When Adrenal Venous Sampling Shows Suppressed Aldosterone Secretion From Both Adrenal Glands - p. 54 26. Section C Corticotropin-Independent Cushing Syndrome - p. 59 27. Case 16 28-Year-Old Woman With Remote History of Adrenal Mass Presenting With New-Onset Hypertension and Weight Gain - p. 62 28. Case 17 26-Year-Old Woman With a Discrepant Workup for Cushing Syndrome Subtype - p. 66 29. Case 18 45-Year-Old Woman With Corticotropin-Independent Cushing Syndrome and Bilateral Adrenal Adenomas - p. 68 30. Case 19 Corticotropin-Independent Cushing Syndrome in a Patient With “Normal” Adrenal Imaging - p. 71 31. Case 20 66-Year-Old Woman With Corticotropin-Independent Hypercortisolism and Bilateral Macronodular Adrenal Hyperplasia - p. 74 32. Case 21 35-Year-Old Woman With Low Bone Density and Fractures - p. 77 33. Case 22 Carney Triad (Pentad) and Adrenal Adenoma With Clinically Important Cortisol Secretory Autonomy - p. 80 34. Section D Adrenal Cortical Carcinoma and Oncocytic Neoplasm - p. 85 35. Case 23 Adrenal Cortical Carcinoma in a Patient With a History of Adrenal Incidentaloma - p. 88 36. Case 24 Unexpected Diagnosis of Adrenal Cortical Carcinoma: Role of Urinary Steroid Profiling - p. 91 37. Case 25 Oncocytic Adrenocortical Carcinoma - p. 94 38. Case 26 Mitotane Therapy in the ENSAT Stage II Adrenocortical Carcinoma - p. 97 39. Case 27 Cortisol-Secreting Metastatic Adrenocortical Carcinoma: Role for Surgical Debulking of the Primary Tumor - p. 100 40. Case 28 Adrenocortical Carcinoma and Severe Cushing Syndrome - p. 103 41. Case 29 Pure Aldosterone-Secreting Adrenocortical Carcinoma - p. 106 42. Case 30 Long-Standing Primary Aldosteronism in a Patient Diagnosed With Metastatic Adrenocortical Carcinoma - p. 109 43. Case 31 Adrenocortical Carcinoma Associated With Lynch Syndrome - p. 112 44. Case 32 Adrenocortical Carcinoma Associated With Multiple Endocrine Neoplasia Type 1 - p. 115 45. Case 33 Adrenocortical Carcinoma Presenting With Inferior Vena Cava Thrombus - p. 118 46. Case 34 Management of Mitotane Therapy in Adrenocortical Carcinoma - p. 121 47. Section E Pheochromocytoma and Paraganglioma - p. 127 48. Case 35 Most Pheochromocytomas Grow Slowly - p. 132 49. Case 36 The “Prebiochemical” Pheochromocytoma - p. 135 50. Case 37 Huge Catecholamine-Secreting Tumor - p. 138 51. Case 38 Metyrosine Use in a Patient With Metastatic Pheochromocytoma - p. 141 52. Case 39 Pheochromocytoma in a Patient With Neurofibromatosis Type 1 - p. 144 53. Case 40 New Diagnosis of Multiple Endocrine Neoplasia Type 2A in a Patient With Bilateral Pheochromocytomas - p. 147 54. Case 41 Pheochromocytoma in a Patient With von Hippel Lindau Disease - p. 150 55. Case 42 Bilateral Pheochromocytoma in a Patient With MYC-Associated Protein X (MAX) Genetic Predisposition - p. 153 56. Case 43 The Cystic Pheochromocytoma - p. 156 57. Case 44 Skull Base and Neck Paragangliomas: Considerations for the Endocrinologist - p. 159 58. Case 45 Cardiac Paraganglioma - p. 162 59. Case 46 Pheochromocytoma in Multiple Endocrine Neoplasia Type 2B - p. 165 60. Case 47 Metastatic Paraganglioma: An Approach to Management and the Use of Serial Imaging to Assess the Rate of Tumor Progression - p. 168 61. Case 48 Metastatic Pheochromocytoma: Role for Ga-68 DOTATATE PET-CT - p. 172 62. Case 49 Carney Triad (Pentad) and Catecholamine-Secreting Paragangliomas - p. 176 63. Case 50 Metastatic Paraganglioma: Role for Systemic Chemotherapy - p. 180 64. Case 51 Cryoablation Therapy for Metastatic Paraganglioma - p. 183 65. Case 52 Paraganglioma in a Patient With Cyanotic Cardiac Disease - p. 186 66. Case 53 Metastatic Paraganglioma—Role for External Beam Radiation Therapy - p. 189 67. Section F Corticotropin-Dependent Hypercortisolism - p. 193 68. Case 54 Corticotropin-Dependent Cushing Syndrome Can Be Frequently Misdiagnosed - p. 197 69. Case 55 Corticotropin-Dependent Cushing Syndrome: Role for Inferior Petrosal Sinus Sampling - p. 201 70. Case 56 Corticotropin-Dependent Cushing Syndrome: When Inferior Petrosal Sinus Sampling Is Not Needed - p. 205 71. Case 57 Severe Corticotropin-Dependent Cushing Syndrome From a Pituitary Adenoma - p. 209 72. Case 58 Ectopic Cushing Syndrome Associated With Multiple Endocrine Neoplasia Type 2B - p. 213 73. Case 59 Ectopic Cushing Syndrome Treated With Cryoablation - p. 215 74. Case 60 Cyclical Ectopic Cushing Syndrome - p. 218 75. Case 61 Mild Cushing Syndrome Associated With Ectopic Corticotropin Secretion - p. 221 76. Case 62 Bilateral Adrenal Cryoablation in Corticotropin-Dependent Cushing Syndrome - p. 224 77. Case 63 Cushing Syndrome Associated With Ectopic Corticotropin and Corticotropin-Releasing Hormone–Secreting Pheochromocytoma - p. 227 78. Case 64 Cushing Syndrome in the Setting of Multiple Endocrine Neoplasia Type 1 - p. 231 79. Section G Other Adrenal Masses - p. 235 80. Case 65 Adrenal Myelolipoma: A Computed Tomography Diagnosis - p. 236 81. Case 66 Adrenal Schwannoma - p. 238 82. Case 67 Trauma-Related Unilateral Adrenal Hemorrhage - p. 241 83. Case 68 Bilateral Adrenal Hemorrhage - p. 244 84. Case 69 Primary Adrenal Teratoma - p. 247 85. Case 70 The Adrenal Stone - p. 250 86. Case 71 Simple Adrenal Cyst - p. 253 87. Case 72 Adrenal Cystic Lymphangioma - p. 255 88. Case 73 Adrenal Hemangioma - p. 257 89. Case 74 Adrenal Ganglioneuroma - p. 259 90. Case 75 42-Year-Old Woman With a Large Composite Adrenal Mass - p. 262 91. Case 76 Primary Adrenal Leiomyosarcoma - p. 265 92. Case 77 Primary Adrenal Lymphoma - p. 268 93. Case 78 39-Year-Old Man With a Large Adrenal Mass - p. 272 94. Case 79 59-Year-Old Man With Enlarging Bilateral Adrenal Masses - p. 274 95. Case 80 65-Year-Old Man With Primary Adrenal Insufficiency - p. 277 96. Case 81 47-Year-Old Man With Primary Adrenal Insufficiency - p. 280 97. Case 82 Bilateral Adrenal Myelolipoma: Think of Congenital Adrenal Hyperplasia - p. 282 98. Case 83 A Unilateral Lipid-Poor Adrenal Mass: An Atypical Presentation of Adrenal Histoplasmosis - p. 285 99. Case 84 Bilateral Macronodular Adrenal Hyperplasia in the Setting of Multiple Endocrine Neoplasia Type 1 - p. 289 100. Case 85 Pseudo-Adrenal Masses - p. 292 101. Section H Adrenal and Ovarian Hyperandrogenism - p. 297 102. Case 86 A Huge Adrenal Myelolipoma in a Patient With a Suboptimally Controlled Congenital Adrenal Hyperplasia - p. 299 103. Case 87 Balancing Glucocorticoid and Androgen Excess in Congenital Adrenal Hyperplasia - p. 302 104. Case 88 Dehydroepiandrosterone Sulfate: The “Love It” or “Hate It” Hormone - p. 305 105. Case 89 Sorting Out the Source of Androgen Excess in a Postmenopausal Woman With an Adrenal and an Ovarian Mass - p. 308 106. Case 90 Primary Testosterone-Secreting Adrenocortical Carcinoma in a Premenopausal Woman - p. 311 107. Case 91 Premenopausal Woman With Testosterone-Secreting Ovarian Tumor - p. 314 108. Case 92 Sorting Out the Source of Androgen Excess in a Postmenopausal Woman With an Adrenal Mass - p. 317 109. Case 93 Testosterone-Secreting Benign Adrenal Adenoma in a Postmenopausal Woman - p. 320 110. Section I Adrenal Disorders in Pregnancy - p. 323 111. Case 94 Malignant Pheochromocytoma in Pregnancy - p. 324 112. Case 95 Catecholamine-Secreting Paraganglioma in Pregnancy - p. 329 113. Case 96 The Peripartum Diagnosis of Pheochromocytoma and a Genetic Mystery Solved - p. 333 114. Case 97 History of Pregnancy in a 41-Year-Old Woman With Undiagnosed Cushing Syndrome - p. 338 115. Case 98 Pregnancy in a Patient With Primary Adrenal Insufficiency - p. 341 116. Case 99 Pregnancy in a Patient With 21-Hydroxylase Deficiency - p. 343 117. Case 100 Primary Aldosteronism in Pregnancy - p. 345 118. Index - p. 349