Mitochondrial Metabolism: An Approach for Disease Management covers mitotherapy from three combined perspectives, Pharmacology, Toxicology and Biochemistry. After an introduction from world-renowned experts, the book's chapters cover the balancing role in reduction/oxidation mitochondria play, mitochondria as targets for therapeutics through its metabolism, mitochondrial contributions to the cell death process, mitochondrial response to environmental toxicants, the mitochondrial role in aging, the impact of calorie restrictive diets, new advances in the identification of altered mitochondria associated signaling pathways in carcinogenesis, and much more.
This book provides bioscientists new horizons to realize the importance of mitochondria in present-day research on therapies dealing with mitochondria associated chronic diseases, including diabetes, cancer and neurodegenerative disorders.
1. Mitochondrial Metabolism - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Contributors - p. Page iv 7. Preface - p. Page vi 8. List of Illustrations - p. Page ix 9. List of Tables - p. Page x 10. Chapter 1 : Mitochondria as balancers of reduction/oxidation for intracellular environment - p. Page x 11. Chapter 2 : Mitochondria as biosynthetic centers and targeted therapeutics - p. Page 14 12. Chapter 3 : Mitochondrial contribution to cell death - p. Page 44 13. Chapter 4 : Mitochondrial response to environmental toxicants - p. Page 58 14. Chapter 5 : Updates on mitochondria, calorie restriction, and aging - p. Page 89 15. Chapter 6 : Mitochondrial metabolism and carcinogenesis - p. Page 114 16. Chapter 7 : Mitochondria and cancer therapy - p. Page 144 17. Chapter 8 : Mitochondrial metabolism in diabetes - p. Page 176 18. Chapter 9 : Mitochondrial abnormalities in neurological disorders - p. Page 188 19. Chapter 10 : Mitochondrial abnormalities in psychological disorders - p. Page 234 20. Chapter 11 : Mitotherapy, an attractive avenue for the future medicine - p. Page 271 21. Index - p. Page 290
Mitochondrial Metabolism: An Approach for Disease Management covers mitotherapy from three combined perspectives, Pharmacology, Toxicology and Biochemistry. After an introduction from world-renowned experts, the book's chapters cover the balancing role in reduction/oxidation mitochondria play, mitochondria as targets for therapeutics through its metabolism, mitochondrial contributions to the cell death process, mitochondrial response to environmental toxicants, the mitochondrial role in aging, the impact of calorie restrictive diets, new advances in the identification of altered mitochondria associated signaling pathways in carcinogenesis, and much more.
This book provides bioscientists new horizons to realize the importance of mitochondria in present-day research on therapies dealing with mitochondria associated chronic diseases, including diabetes, cancer and neurodegenerative disorders.
1. Mitochondrial Metabolism - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Contributors - p. Page iv 7. Preface - p. Page vi 8. List of Illustrations - p. Page ix 9. List of Tables - p. Page x 10. Chapter 1 : Mitochondria as balancers of reduction/oxidation for intracellular environment - p. Page x 11. Chapter 2 : Mitochondria as biosynthetic centers and targeted therapeutics - p. Page 14 12. Chapter 3 : Mitochondrial contribution to cell death - p. Page 44 13. Chapter 4 : Mitochondrial response to environmental toxicants - p. Page 58 14. Chapter 5 : Updates on mitochondria, calorie restriction, and aging - p. Page 89 15. Chapter 6 : Mitochondrial metabolism and carcinogenesis - p. Page 114 16. Chapter 7 : Mitochondria and cancer therapy - p. Page 144 17. Chapter 8 : Mitochondrial metabolism in diabetes - p. Page 176 18. Chapter 9 : Mitochondrial abnormalities in neurological disorders - p. Page 188 19. Chapter 10 : Mitochondrial abnormalities in psychological disorders - p. Page 234 20. Chapter 11 : Mitotherapy, an attractive avenue for the future medicine - p. Page 271 21. Index - p. Page 290
