Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health, Second Edition, provides a systematic evaluation of representative engineered nanomaterials (ENM) of high volume production and their high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies, and the general public need to know about nanosafety.
Written by leading international experts in nanotoxicology and nanomedicine, this book gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers, and patients. All chapters have been updated with new sections on the endocrine system and other organ systems. In addition, other newly added sections include introductory chapters on the physio-chemical characterization of nanomaterials and interactions between nanomaterials and biological systems, as well as a new chapter that explores risk assessment and management of nanomaterials.
This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, also detailing the clinical and pathological consequences of such exposure in the human population.
1. Cover - p. i 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. ii 5. Contributors - p. iv 6. About the Editors - p. xiii 7. Preface - p. xiv 8. Section A: Engineered nanomaterials: Hazard, exposure, risk assessment - p. xvii 9. Chapter 1: Bio–Nano Interactions - p. xvii 10. Chapter 2: Physicochemical Characterization - p. 14 11. Chapter 3: Toxicity Tests: In Vitro and In Vivo - p. 49 12. Chapter 4: Computational Approaches - p. 82 13. Chapter 5: Exposure Assessment - p. 102 14. Chapter 6: Biomonitoring - p. 123 15. Chapter 7: Regulation and Legislation - p. 158 16. Chapter 8: Risk Assessment and Risk Management - p. 188 17. Section B: Engineered nanomaterials: Adverse effects on human health - p. 222 18. Chapter 9: Respiratory System, Part One: Basic Mechanisms - p. 222 19. Chapter 10: Respiratory System, Part Two: Allergy and Asthma - p. 242 20. Chapter 11: Cardiovascular System - p. 253 21. Chapter 12: Neurological System - p. 274 22. Chapter 13: Immune System - p. 312 23. Chapter 14: Endocrine System - p. 337 24. Chapter 15: Skin - p. 355 25. Chapter 16: Gastrointestinal System - p. 380 26. Chapter 17: Reproduction and Development - p. 396 27. Chapter 18: Genotoxicity and Cancer - p. 421 28. Glossary - p. 445 29. Index - p. 454
Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health, Second Edition, provides a systematic evaluation of representative engineered nanomaterials (ENM) of high volume production and their high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies, and the general public need to know about nanosafety.
Written by leading international experts in nanotoxicology and nanomedicine, this book gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers, and patients. All chapters have been updated with new sections on the endocrine system and other organ systems. In addition, other newly added sections include introductory chapters on the physio-chemical characterization of nanomaterials and interactions between nanomaterials and biological systems, as well as a new chapter that explores risk assessment and management of nanomaterials.
This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, also detailing the clinical and pathological consequences of such exposure in the human population.
1. Cover - p. i 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. ii 5. Contributors - p. iv 6. About the Editors - p. xiii 7. Preface - p. xiv 8. Section A: Engineered nanomaterials: Hazard, exposure, risk assessment - p. xvii 9. Chapter 1: Bio–Nano Interactions - p. xvii 10. Chapter 2: Physicochemical Characterization - p. 14 11. Chapter 3: Toxicity Tests: In Vitro and In Vivo - p. 49 12. Chapter 4: Computational Approaches - p. 82 13. Chapter 5: Exposure Assessment - p. 102 14. Chapter 6: Biomonitoring - p. 123 15. Chapter 7: Regulation and Legislation - p. 158 16. Chapter 8: Risk Assessment and Risk Management - p. 188 17. Section B: Engineered nanomaterials: Adverse effects on human health - p. 222 18. Chapter 9: Respiratory System, Part One: Basic Mechanisms - p. 222 19. Chapter 10: Respiratory System, Part Two: Allergy and Asthma - p. 242 20. Chapter 11: Cardiovascular System - p. 253 21. Chapter 12: Neurological System - p. 274 22. Chapter 13: Immune System - p. 312 23. Chapter 14: Endocrine System - p. 337 24. Chapter 15: Skin - p. 355 25. Chapter 16: Gastrointestinal System - p. 380 26. Chapter 17: Reproduction and Development - p. 396 27. Chapter 18: Genotoxicity and Cancer - p. 421 28. Glossary - p. 445 29. Index - p. 454
