Animal Models of Disease, Part C, Volume 192 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors, The current models unravel the molecular mechanisms underlying the intricate pathophysiology of Alzheimer’s disease using Zebrafish, Colitis mouse model, Matching model with mechanism: appropriate animal models for studying various aspects of diabetes pathophysiology, Human cancer cells xenografts to assess the efficacy of granulysin-based therapeutics, and much more.
Additional sections cover Antimicrobial regime for gut microbiota depletion in experimental mice models, Evaluating polyglutamine protein aggregation and toxicity in transgenic Caenorhabditis elegans models of Huntington's disease, A model of intraperitoneal ovarian cancer to study tumor responses to radioimmunotherapy, Metallic nanoparticles biodistribution for the study of lymphoma in animal models, Stereotactic injection of murine brain tumor cells for neuro-oncology studies, Evaluating amyloid-beta aggregation and toxicity in transgenic Caenorhabditis elegans models of Alzheimer's disease, and much more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Series Page - p. iii 5. Copyright - p. iii 6. Contributors - p. iii 7. Animal models of disease: Achievements and challenges - p. xv 8. Chapter One: Characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors - p. 1 9. Chapter Two: The current models unravel the molecular mechanisms underlying the intricate pathophysiology of Alzheimer's disease using zebrafish - p. 17 10. Chapter Three: A mouse model to assess immunotherapy-related colitis - p. 33 11. Chapter Four: Matching model with mechanism: Appropriate rodent models for studying various aspects of diabetes pathophysiology - p. 39 12. Chapter Five: Induction of sepsis in a rat model by the cecal ligation and puncture technique. Application for the study of experimental acute renal failure - p. 69 13. Chapter Six: Human cancer cells xenografts to assess the efficacy of granulysin-based therapeutics - p. 83 14. Chapter Seven: Antimicrobial regime for gut microbiota depletion in experimental mice models - p. 101 15. Chapter Eight: Evaluating polyglutamine protein aggregation and toxicity in transgenic Caenorhabditis elegans models of Huntington's disease - p. 115 16. Chapter Nine: Development of an in vivo ovarian cancer peritoneal carcinomatosis model for radioimmunotherapy testing - p. 131 17. Chapter Ten: Metallic nanoparticles biodistribution for the study of lymphoma in animal models - p. 159 18. Chapter Eleven: Stereotactic injection of murine brain tumor cells for neuro-oncology studies - p. 181 19. Chapter Twelve: Evaluating amyloid-beta aggregation and toxicity in transgenic Caenorhabditis elegans models of Alzheimer’s disease - p. 189
Animal Models of Disease, Part C, Volume 192 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors, The current models unravel the molecular mechanisms underlying the intricate pathophysiology of Alzheimer’s disease using Zebrafish, Colitis mouse model, Matching model with mechanism: appropriate animal models for studying various aspects of diabetes pathophysiology, Human cancer cells xenografts to assess the efficacy of granulysin-based therapeutics, and much more.
Additional sections cover Antimicrobial regime for gut microbiota depletion in experimental mice models, Evaluating polyglutamine protein aggregation and toxicity in transgenic Caenorhabditis elegans models of Huntington's disease, A model of intraperitoneal ovarian cancer to study tumor responses to radioimmunotherapy, Metallic nanoparticles biodistribution for the study of lymphoma in animal models, Stereotactic injection of murine brain tumor cells for neuro-oncology studies, Evaluating amyloid-beta aggregation and toxicity in transgenic Caenorhabditis elegans models of Alzheimer's disease, and much more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Series Page - p. iii 5. Copyright - p. iii 6. Contributors - p. iii 7. Animal models of disease: Achievements and challenges - p. xv 8. Chapter One: Characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors - p. 1 9. Chapter Two: The current models unravel the molecular mechanisms underlying the intricate pathophysiology of Alzheimer's disease using zebrafish - p. 17 10. Chapter Three: A mouse model to assess immunotherapy-related colitis - p. 33 11. Chapter Four: Matching model with mechanism: Appropriate rodent models for studying various aspects of diabetes pathophysiology - p. 39 12. Chapter Five: Induction of sepsis in a rat model by the cecal ligation and puncture technique. Application for the study of experimental acute renal failure - p. 69 13. Chapter Six: Human cancer cells xenografts to assess the efficacy of granulysin-based therapeutics - p. 83 14. Chapter Seven: Antimicrobial regime for gut microbiota depletion in experimental mice models - p. 101 15. Chapter Eight: Evaluating polyglutamine protein aggregation and toxicity in transgenic Caenorhabditis elegans models of Huntington's disease - p. 115 16. Chapter Nine: Development of an in vivo ovarian cancer peritoneal carcinomatosis model for radioimmunotherapy testing - p. 131 17. Chapter Ten: Metallic nanoparticles biodistribution for the study of lymphoma in animal models - p. 159 18. Chapter Eleven: Stereotactic injection of murine brain tumor cells for neuro-oncology studies - p. 181 19. Chapter Twelve: Evaluating amyloid-beta aggregation and toxicity in transgenic Caenorhabditis elegans models of Alzheimer’s disease - p. 189
