Antidotes to Toxins and Drugs: From Natural Sources to Drug Discovery in Toxicology presents recent advances in the discovery of natural antidotes to toxins, drug intoxications and overdoses in pharmacology, drug discovery and toxicology. The text provides detailed information about toxins and their natural antidotes, along with the identification and screening of antidotes for drug intoxications and overdoses. Written by a global team of experts, it describes the potential uses of natural products in toxicology and their applications in medicine and in the pharmaceutical sciences. This book will be a key resource for drug developers, medicinal chemists and toxicologists, among others.Sections shine a particular focus on mechanisms of action, various principles in pharmacokinetics and pharmacodynamics terms, and possible sources and synthesis techniques for these phytochemicals.
1. Antidotes to Toxins and Drugs - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. List of Illustrations - p. Page viii 9. List of Tables - p. Page ix 10. Chapter 1 : Antidotes to drug intoxications or drug overdoses - p. Page ix 11. Chapter 2 : Antidotes to insect toxins, bee venom; wasp and hornet venoms - p. Page 28 12. Chapter 3 : Antidotes to reptile toxins chemical composition of snake venoms; toxic effects of snake venom - p. Page 66 13. Chapter 4 : Antidotes to mycotoxins and mushroom toxins - p. Page 90 14. Chapter 5 : Antidotes to nonreptile animal toxins - p. Page 114 15. Chapter 6 : Antidotes to toxic substances from the marine world - p. Page 142 16. Chapter 7 : Antidotes to aflatoxicosis in humans - p. Page 160 17. Chapter 8 : Drug-induced liver injury: toxins and antidotes - p. Page 185 18. Chapter 9 : Natural toxins and drug discovery opportunities - p. Page 213 19. Chapter 10 : Antidotes to toxins and drugs in the European Union: public health, policy, and regulatory framework☆ - p. Page 251 20. Chapter 11 : Benefits and safety of probiotics in gastrointestinal diseases - p. Page 275 21. Chapter 12 : Clozapine—serious adverse effects and clinical management - p. Page 310 22. Chapter 13 : Iatrogenic opioid and hypnotics withdrawal syndromes in adults in intensive care - p. Page 348 23. Chapter 14 : Laboratory evaluation of intoxications: toxins and drugs - p. Page 382 24. Chapter 15 : Antidodes in esthetic medicine - p. Page 407 25. Index - p. Page 433
Antidotes to Toxins and Drugs: From Natural Sources to Drug Discovery in Toxicology presents recent advances in the discovery of natural antidotes to toxins, drug intoxications and overdoses in pharmacology, drug discovery and toxicology. The text provides detailed information about toxins and their natural antidotes, along with the identification and screening of antidotes for drug intoxications and overdoses. Written by a global team of experts, it describes the potential uses of natural products in toxicology and their applications in medicine and in the pharmaceutical sciences. This book will be a key resource for drug developers, medicinal chemists and toxicologists, among others.Sections shine a particular focus on mechanisms of action, various principles in pharmacokinetics and pharmacodynamics terms, and possible sources and synthesis techniques for these phytochemicals.
1. Antidotes to Toxins and Drugs - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. List of Illustrations - p. Page viii 9. List of Tables - p. Page ix 10. Chapter 1 : Antidotes to drug intoxications or drug overdoses - p. Page ix 11. Chapter 2 : Antidotes to insect toxins, bee venom; wasp and hornet venoms - p. Page 28 12. Chapter 3 : Antidotes to reptile toxins chemical composition of snake venoms; toxic effects of snake venom - p. Page 66 13. Chapter 4 : Antidotes to mycotoxins and mushroom toxins - p. Page 90 14. Chapter 5 : Antidotes to nonreptile animal toxins - p. Page 114 15. Chapter 6 : Antidotes to toxic substances from the marine world - p. Page 142 16. Chapter 7 : Antidotes to aflatoxicosis in humans - p. Page 160 17. Chapter 8 : Drug-induced liver injury: toxins and antidotes - p. Page 185 18. Chapter 9 : Natural toxins and drug discovery opportunities - p. Page 213 19. Chapter 10 : Antidotes to toxins and drugs in the European Union: public health, policy, and regulatory framework☆ - p. Page 251 20. Chapter 11 : Benefits and safety of probiotics in gastrointestinal diseases - p. Page 275 21. Chapter 12 : Clozapine—serious adverse effects and clinical management - p. Page 310 22. Chapter 13 : Iatrogenic opioid and hypnotics withdrawal syndromes in adults in intensive care - p. Page 348 23. Chapter 14 : Laboratory evaluation of intoxications: toxins and drugs - p. Page 382 24. Chapter 15 : Antidodes in esthetic medicine - p. Page 407 25. Index - p. Page 433
