Apoptosis in Health and Disease - Part B, Volume 126 in the Advances in Protein Chemistry and Structural Biology focuses on apoptotic responses in numerous conditions - from bacterial and parasite infections, to pathological states such as oxidative stress, pulmonary hypertension, and different cancer types, etc. In addition, the book provides therapeutic strategies for targeting apoptosis. These new advanced understandings are playing a major influence in drug discovery and the introduction of new therapies that target the cell death process.
Apoptosis, or programmed cell death, is the mechanism by which cells die either physiologically or pathologically. Vast research in apoptosis has advanced our understanding of basic physiological and pathological processes occurring in cells, organs and organisms, and its role in a number of diseases.
1. Cover image - p. i 2. Table of Contents - p. iii 3. Copyright - p. iii 4. Contributors - p. iii 5. Chapter One: Structural insights of macromolecules involved in bacteria-induced apoptosis in the pathogenesis of human diseases - p. 1 6. Chapter Two: Apoptosis: A friend or foe in mesenchymal stem cell-based immunosuppression - p. 39 7. Chapter Three: Differential roles of farnesoid X receptor (FXR) in modulating apoptosis in cancer cells - p. 75 8. Chapter Four: Alternative approaches to overcome chemoresistance to apoptosis in cancer - p. 91 9. Chapter Five: Recent developments in CCR5 regulation for HIV cure - p. 123 10. Chapter Six: RNA-seeded membraneless bodies: Role of tandemly repeated RNA - p. 151 11. Chapter Seven: Cell death mechanisms and their roles in pregnancy related disorders - p. 195 12. Chapter Eight: The concept of protein folding/unfolding and its impacts on human health - p. 227 13. Chapter Nine: Apoptosis in health and diseases of the eye and brain - p. 279 14. Chapter Ten: Apoptotic signals at the endoplasmic reticulum-mitochondria interface - p. 307
Apoptosis in Health and Disease - Part B, Volume 126 in the Advances in Protein Chemistry and Structural Biology focuses on apoptotic responses in numerous conditions - from bacterial and parasite infections, to pathological states such as oxidative stress, pulmonary hypertension, and different cancer types, etc. In addition, the book provides therapeutic strategies for targeting apoptosis. These new advanced understandings are playing a major influence in drug discovery and the introduction of new therapies that target the cell death process.
Apoptosis, or programmed cell death, is the mechanism by which cells die either physiologically or pathologically. Vast research in apoptosis has advanced our understanding of basic physiological and pathological processes occurring in cells, organs and organisms, and its role in a number of diseases.
1. Cover image - p. i 2. Table of Contents - p. iii 3. Copyright - p. iii 4. Contributors - p. iii 5. Chapter One: Structural insights of macromolecules involved in bacteria-induced apoptosis in the pathogenesis of human diseases - p. 1 6. Chapter Two: Apoptosis: A friend or foe in mesenchymal stem cell-based immunosuppression - p. 39 7. Chapter Three: Differential roles of farnesoid X receptor (FXR) in modulating apoptosis in cancer cells - p. 75 8. Chapter Four: Alternative approaches to overcome chemoresistance to apoptosis in cancer - p. 91 9. Chapter Five: Recent developments in CCR5 regulation for HIV cure - p. 123 10. Chapter Six: RNA-seeded membraneless bodies: Role of tandemly repeated RNA - p. 151 11. Chapter Seven: Cell death mechanisms and their roles in pregnancy related disorders - p. 195 12. Chapter Eight: The concept of protein folding/unfolding and its impacts on human health - p. 227 13. Chapter Nine: Apoptosis in health and diseases of the eye and brain - p. 279 14. Chapter Ten: Apoptotic signals at the endoplasmic reticulum-mitochondria interface - p. 307
