Autophagy and Metabolism: Potential Target for Cancer Therapy presents updates on autophagy in cancer metabolism and how it can be used to develop new, more efficient treatments. Written by experts in the field, the book presents recent research and explains how to translate it to the clinical setting. Sections discuss tumor cell metabolism and autophagy as therapeutic targets, autophagy regulation in cancer, signaling pathways in metabolic dysregulation in solid tumors, metabolic stress and cell death pathways, and the role of the tumor microenvironment. In addition, topics cover combined targeting autophagy, metabolism for cancer therapy, and the autophagy effect on immune cell metabolism.
This will be a valuable resource for researchers, oncologists, graduate students, and members of the biomedical field who are interested in learning more about the interaction between autophagy and cancer metabolism.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xi 7. Preface - p. xv 8. Chapter 1. Metabolic dysregulation in cancer progression - p. 1 9. Chapter 2. Molecular dynamics of autophagy in cancer metabolism - p. 41 10. Chapter 3. Tumor cell metabolism and autophagy as therapeutic targets - p. 73 11. Chapter 4. Autophagy regulation in cancer: current knowledge on action and therapy - p. 109 12. Chapter 5. Signaling pathways in metabolic dysregulation in solid tumors - p. 119 13. Chapter 6. Autophagy in arsenic exposed population and cancer patients - p. 141 14. Chapter 7. Autophagy in cancer-associated fibroblasts: biology and targeting - p. 163 15. Chapter 8. Autophagy and metabolic regulation in cancer and its application in drug discovery - p. 177 16. Chapter 9. Mitophagy in cancer and cancer stem cells: a role in metabolic reprogramming - p. 195 17. Chapter 10. Combined targeting autophagy and metabolism for cancer therapy - p. 215 18. Chapter 11. Designing metabolic target-specific inhibitors for cancer therapy - p. 239 19. Chapter 12. Interplay between gut microbiota and autophagy in human health - p. 281 20. Chapter 13. Autophagy in infection-mediated cancers - p. 301 21. Index - p. 333
Autophagy and Metabolism: Potential Target for Cancer Therapy presents updates on autophagy in cancer metabolism and how it can be used to develop new, more efficient treatments. Written by experts in the field, the book presents recent research and explains how to translate it to the clinical setting. Sections discuss tumor cell metabolism and autophagy as therapeutic targets, autophagy regulation in cancer, signaling pathways in metabolic dysregulation in solid tumors, metabolic stress and cell death pathways, and the role of the tumor microenvironment. In addition, topics cover combined targeting autophagy, metabolism for cancer therapy, and the autophagy effect on immune cell metabolism.
This will be a valuable resource for researchers, oncologists, graduate students, and members of the biomedical field who are interested in learning more about the interaction between autophagy and cancer metabolism.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xi 7. Preface - p. xv 8. Chapter 1. Metabolic dysregulation in cancer progression - p. 1 9. Chapter 2. Molecular dynamics of autophagy in cancer metabolism - p. 41 10. Chapter 3. Tumor cell metabolism and autophagy as therapeutic targets - p. 73 11. Chapter 4. Autophagy regulation in cancer: current knowledge on action and therapy - p. 109 12. Chapter 5. Signaling pathways in metabolic dysregulation in solid tumors - p. 119 13. Chapter 6. Autophagy in arsenic exposed population and cancer patients - p. 141 14. Chapter 7. Autophagy in cancer-associated fibroblasts: biology and targeting - p. 163 15. Chapter 8. Autophagy and metabolic regulation in cancer and its application in drug discovery - p. 177 16. Chapter 9. Mitophagy in cancer and cancer stem cells: a role in metabolic reprogramming - p. 195 17. Chapter 10. Combined targeting autophagy and metabolism for cancer therapy - p. 215 18. Chapter 11. Designing metabolic target-specific inhibitors for cancer therapy - p. 239 19. Chapter 12. Interplay between gut microbiota and autophagy in human health - p. 281 20. Chapter 13. Autophagy in infection-mediated cancers - p. 301 21. Index - p. 333
