• Fully revised throughout – including new and expanded coverage of human immune system; neuroimmunology; cancer immunotherapy; intracellular sensors of innate immunity, therapeutic use of monoclonal antibodies, regulation of migration events during T cell-B cell interactions, regulatory and transcriptional events in germinal center formation, immunology of infectious diseases including coronaviruses, human immunodeficiency disorders, and immunology of HIV.
1. Cellular and Molecular Immunology - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. Preface - p. vii 8. Get the Most Out of Cellular and Molecular Immunology 11e – Accompanying Electronic Resources - p. ix 9. 1. Overview of the Immune System - p. 1 10. 2. Cells and Tissues of the Immune System - p. 13 11. 3. Leukocyte Circulation and Migration Into Tissues - p. 42 12. 4. Innate Immunity - p. 61 13. 5. Antibodies And Antigens - p. 105 14. 6. Antigen Presentation to T Lymphocytes and the Role of Major Histocompatibility Complex Molecules - p. 126 15. 7. Immune Receptors and Signal Transduction - p. 154 16. 8. Lymphocyte Development and Antigen Receptor Gene Rearrangement - p. 191 17. 9. Activation and Regulation of T Lymphocytes - p. 221 18. Differentiation and Functions of CD4+ Effector T Cells - p. 239 19. Differentiation and Functions of CD8+ Effector T Cells - p. 257 20. 12. B-Cell Activation and Antibody Production - p. 267 21. 13. Effector Mechanisms of Humoral Immunity - p. 293 22. 14. Specialized Immunity at Epithelial Barriers and in Immune-Privileged Tissues - p. 318 23. 15. Immunologic Tolerance and Autoimmunity - p. 344 24. 16. Immunity to Microbes - p. 367 25. 17. Transplantation Immunology - p. 391 26. 18. Tumor Immunology - p. 417 27. 19. Hypersensitivity Disorders - p. 440 28. 20. Allergy - p. 462 29. 21. Congenital and Acquired Immunodeficiencies - p. 484 30. Glossary - p. 511 31. Appendix I. Principal Features of Selected CD Molecules - p. 534 32. Appendix 1O. Review Questions and Answers - p. 541.e1 33. Appendix II. Cytokines - p. 542 34. Appendix 2O - p. 545.e1 35. Appendix III. Laboratory Techniques Commonly Used in Immunology - p. 546 36. Appendix 3O. Clinical Cases - p. 560.e1 37. Index - p. 561
• Fully revised throughout – including new and expanded coverage of human immune system; neuroimmunology; cancer immunotherapy; intracellular sensors of innate immunity, therapeutic use of monoclonal antibodies, regulation of migration events during T cell-B cell interactions, regulatory and transcriptional events in germinal center formation, immunology of infectious diseases including coronaviruses, human immunodeficiency disorders, and immunology of HIV.
1. Cellular and Molecular Immunology - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. Preface - p. vii 8. Get the Most Out of Cellular and Molecular Immunology 11e – Accompanying Electronic Resources - p. ix 9. 1. Overview of the Immune System - p. 1 10. 2. Cells and Tissues of the Immune System - p. 13 11. 3. Leukocyte Circulation and Migration Into Tissues - p. 42 12. 4. Innate Immunity - p. 61 13. 5. Antibodies And Antigens - p. 105 14. 6. Antigen Presentation to T Lymphocytes and the Role of Major Histocompatibility Complex Molecules - p. 126 15. 7. Immune Receptors and Signal Transduction - p. 154 16. 8. Lymphocyte Development and Antigen Receptor Gene Rearrangement - p. 191 17. 9. Activation and Regulation of T Lymphocytes - p. 221 18. Differentiation and Functions of CD4+ Effector T Cells - p. 239 19. Differentiation and Functions of CD8+ Effector T Cells - p. 257 20. 12. B-Cell Activation and Antibody Production - p. 267 21. 13. Effector Mechanisms of Humoral Immunity - p. 293 22. 14. Specialized Immunity at Epithelial Barriers and in Immune-Privileged Tissues - p. 318 23. 15. Immunologic Tolerance and Autoimmunity - p. 344 24. 16. Immunity to Microbes - p. 367 25. 17. Transplantation Immunology - p. 391 26. 18. Tumor Immunology - p. 417 27. 19. Hypersensitivity Disorders - p. 440 28. 20. Allergy - p. 462 29. 21. Congenital and Acquired Immunodeficiencies - p. 484 30. Glossary - p. 511 31. Appendix I. Principal Features of Selected CD Molecules - p. 534 32. Appendix 1O. Review Questions and Answers - p. 541.e1 33. Appendix II. Cytokines - p. 542 34. Appendix 2O - p. 545.e1 35. Appendix III. Laboratory Techniques Commonly Used in Immunology - p. 546 36. Appendix 3O. Clinical Cases - p. 560.e1 37. Index - p. 561
