The only reference available that synthesizes this vast subspecialty into a single trustworthy resource, Cornea, 5th Edition, provides state-of-the-art coverage of the expanding range of contemporary corneal surgery, new diagnostic and imaging technologies, and medical management of corneal and external disease as well as ocular surface disease. Drs. Mark J. Mannis, Edward J. Holland, and a team of more than 200 global experts keep you up to date with both common and more obscure diseases and disorders and the best route to effective treatment and management, making this two-volume text a must-have resource for residents and fellows, general ophthalmologists, and seasoned cornea specialists.
Features more than 2,300 exceptionally clear illustrations, diagnostic images, and step-by-step surgical photographs that offer superb visual guidance.
Contains 14 new chapters, including Nanothin DSAEK, Aqueous Deficiency Dry Eye Syndrome, Evaluation of Recurrent Corneal Erosions, Evaluation of the Corneal Ulcer, Contemporary Approaches to the Biosynthetic Cornea, and Topography Guided Photorefractive Keratectomy, and more.
Includes more than 80 video clips of current corneal surgery techniques, including new clips of the application of cryopreserved amniotic membrane in the treatment of acute stevens, penetrating keratoplasty, DM rupture management in STALK and in the keratonconus patient, and KAMRA corneal inlay implantation.
Covers the latest developments in ocular surface transplantation, including new chapters on Conjunctival Limbal Autograft (CLAU); Living Related Conjunctival Limbal Allograft (Lr-CLAL); Keratolimbal Allograft; Cultivated Limbal Epithelial Transplantation; Simple Limbal Epithelial Transplantation; and Outcomes of Ocular Surface Transplantation.
Provides key point overviews in each chapter that offer easier access to crucial information.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Preface - p. xiii 6. Acknowledgments - p. xiv 7. Dedication - p. xv 8. Acknowledgments to the Founding Editors - p. xvi 9. List of Contributors - p. xvii 10. Videos - p. xxix 11. PART I. Basic Science: Cornea, Sclera, Ocular Adnexa Anatomy, Physiology, and Pathophysiologic Responses - p. xxix 12. 1. Cornea and Sclera: Anatomy and Physiology - p. 1.e1 13. 2. The Conjunctiva: Anatomy and Physiology - p. 23.e1 14. 3. Tear Film - p. 31.e1 15. 4. Eyelids and the Corneal Surface - p. 40.e1 16. 5. A Matrix of Pathologic Responses in the Cornea - p. 45.e1 17. Examining and Imaging the Cornea and External Eye - p. 45.e23 18. SECTION 1. Basic Evaluation of the Cornea and External Eye - p. 45.e23 19. 6. Examination of the Lids - p. 46.e1 20. 7. Slit Lamp Examination and Photography - p. 53.e1 21. 8. Tear Film and Corneal Diagnostic Techniques - p. 81.e1 22. SECTION 2. Laboratory Investigations - p. 89 23. 9. Practical Ophthalmic Microbiology for the Detection of Corneal Pathogens - p. 90.e1 24. 10. Molecular Genetics of Corneal Disease - p. 99.e1 25. SECTION 3. Imaging Techniques of the Cornea - p. 110 26. 11. Keratometry and Topography - p. 111.e1 27. 12. Corneal Shape Analysis and Biomechanical Assessment - p. 124.e1 28. 13. Specular Microscopy - p. 130.e1 29. 14. Confocal Microscopy - p. 152.e1 30. 15. Clinical Applications of Confocal Microscopy - p. 162.e1 31. 16. High-Resolution Ultrasound - p. 171.e1 32. 17. Anterior Segment Optical Coherence Tomography - p. 179.e1 33. PART III. Differential Diagnosis of Selected Problems in Cornea and External Eye Disease - p. 184 34. 18. Congenital Corneal Opacities: Diagnosis and Management - p. 185.e1 35. 19. Peripheral Corneal Disease - p. 209.e1 36. 20. Evaluation of the Corneal Ulcer - p. 218.e1 37. 21. Evaluation of Recurrent Corneal Erosions - p. 222.e1 38. 22. Corneal Deposits - p. 226.e1 39. 23. The Red Eye - p. 239.e1 40. PART IV. Eye Banking - p. 245 41. 24. Eye Banking: Structure and Function - p. 246.e1 42. 25. Medical Standards for Eye Banking - p. 250.e1 43. The Ocular Adnexa - p. 258 44. SECTION 1. Diseases of the Lid: Anatomic Abnormalities - p. 258 45. 26. Malposition of the Eyelids - p. 259.e1 46. SECTION 2. Diseases of the Lid: Tumors, Inflammation, and Infection - p. 275 47. 27. Benign Lid Tumors - p. 276.e1 48. 28. Malignant Eyelid Tumors - p. 294.e1 49. 29. Blepharitis: Overview and Classification - p. 308.e1 50. 30. Eyelid Infections - p. 312.e1 51. SECTION 3. Disorders of Tear Production and the Lacrimal System - p. 320 52. 31. Dry Eye Overview: Classification and Treatment Algorithm - p. 321.e1 53. 32. Aqueous Deficiency Dry Eye Syndrome - p. 329.e1 54. 33. Meibomian Gland Dysfunction and Evaporative Dry Eye - p. 336.e1 55. 34. Dacryoadenitis, Dacryocystitis, and Canaliculitis - p. 345.e1 56. 35. Epiphora - p. 352.e1 57. The Conjunctiva - p. 357 58. SECTION 1. Conjunctivitis - p. 357 59. 36. Conjunctivitis: An Overview and Classification - p. 358.e1 60. 37. Bacterial Conjunctivitis - p. 370.e1 61. 38. Viral Conjunctivitis - p. 377.e1 62. 39. Chlamydial Infections - p. 386.e1 63. 40. Ophthalmia Neonatorum - p. 394.e1 64. 41. Parinaud Oculoglandular Syndrome - p. 400.e1 65. 42. Seasonal and Perennial Allergic Conjunctivitis - p. 407.e1 66. 43. Vernal and Atopic Keratoconjunctivitis - p. 413.e1 67. 44. Giant Papillary Conjunctivitis - p. 421.e1 68. 45. Mucous Membrane Pemphigoid - p. 427.e1 69. 46. Erythema Multiforme, Stevens-Johnson Syndrome, and Toxic Epidermal Necrolysis - p. 435.e1 70. 47. Toxic Conjunctivitis - p. 450.e1 71. 48. Superior Limbic Keratoconjunctivitis - p. 458.e1 72. 49. Ligneous Conjunctivitis - p. 465.e1 73. 50. Conjunctivochalasis - p. 471.e1 74. SECTION 2. Conjunctival Disease: Tumors - p. 477 75. 51. Epithelial Tumors of the Conjunctiva - p. 478.e1 76. 52. Medical and Surgical Management of Ocular Surface Squamous Neoplasia - p. 497.e1 77. 53. Melanocytic Neoplasms of the Conjunctiva - p. 507.e1 78. 54. Subepithelial Tumors of the Conjunctiva - p. 516.e1 79. Diseases of the Cornea - p. 539 80. SECTION 1. Developmental Abnormalities of Cornea - p. 539 81. 55. Developmental Corneal Anomalies of Size and Shape - p. 540.e1 82. 56. Axenfeld-Rieger Syndrome - p. 551.e1 83. 57. Peters Anomaly - p. 558.e1 84. SECTION 2. Corneal Manifestations of Systemic Disease and Therapies - p. 560 85. 58. Corneal Manifestations of Metabolic Diseases - p. 561.e1 86. 59. Skeletal and Connective Tissue Disorders With Anterior Segment Manifestations - p. 586.e1 87. 60. Granulomatosis With Polyangiitis and Other Systemic Inflammatory Diseases - p. 603.e1 88. 61. Nutritional Disorders - p. 613.e1 89. 62. Hematologic Diseases and Malignancies - p. 624.e1 90. 63. Endocrine Disease and the Cornea - p. 631.e1 91. 64. Dermatologic Disorders and the Cornea - p. 640.e1 92. 65. Infectious Disease: Ocular Manifestations - p. 653.e1 93. 66. Corneal and External Ocular Infections in Acquired Immunodeficiency Syndrome - p. 664.e1 94. 67. Ocular Graft-Versus-Host Disease - p. 673.e1 95. 68. Corneal Manifestations of Local and Systemic Therapies - p. 686.e1 96. SECTION 3. Corneal Dystrophies, Ectatic Disorders, and Degenerations - p. 695 97. 69. Corneal Dystrophy Classification - p. 696.e1 98. 70. Anterior Corneal Dystrophies - p. 701.e1 99. 71. The Stromal Dystrophies - p. 712.e1 100. 72. Descemet Membrane and Endothelial Dystrophies - p. 730.e1 101. 73. Noninflammatory Ectatic Disorders - p. 749.e1 102. 74. Iridocorneal Endothelial Syndrome - p. 771.e1 103. 75. Corneal and Conjunctival Degenerations - p. 784.e1 104. SECTION 4. Corneal Infections - p. 801 105. 76. Bacterial Keratitis - p. 802.e1 106. 77. Nontuberculous Mycobacteria Keratitis - p. 825.e1 107. 78. Herpes Simplex Keratitis - p. 832.e1 108. 79. Herpes Zoster Keratitis - p. 861.e1 109. 80. Less Common Viral Corneal Infections - p. 873.e1 110. 81. Fungal Keratitis - p. 880.e1 111. Acanthamoeba and Other Parasitic Corneal Infections - p. 896.e1 112. 83. Corneal Diseases in the Developing World - p. 907.e1 113. SECTION 5. Interstitial Keratitis - p. 916 114. 84. Syphilitic Keratitis - p. 917.e1 115. 85. Nonsyphilitic Interstitial Keratitis - p. 927.e1 116. SECTION 6. Noninfectious Keratopathy - p. 937 117. 86. Filamentary Keratitis - p. 938.e1 118. 87. Superficial Punctate Keratitis of Thygeson - p. 942.e1 119. 88. Neurotrophic Keratitis - p. 946.e1 120. 89. Factitious Keratoconjunctivitis - p. 954.e1 121. SECTION 7. Immunologic Disorders of the Cornea - p. 960 122. 90. Corneal Disease in Rheumatoid Arthritis - p. 961.e1 123. 91. Corneal Disease Associated With Nonrheumatoid Collagen-Vascular Disease - p. 974.e1 124. 92. Phlyctenular Keratoconjunctivitis and Marginal Staphylococcal Keratitis - p. 984.e1 125. 93. Mooren Ulcer - p. 990.e1 126. SECTION 8. Corneal Trauma - p. 995 127. 94. Mechanical Injury - p. 996.e1 128. 95. Chemical and Thermal Injuries of the Eye - p. 1012.e1 129. 96. Corneal Complications of Intraocular Surgery - p. 1024.e1 130. 97. External Eye Manifestations of Biological and Chemical Warfare - p. 1042.e1 131. SECTION 9. Contact Lenses - p. 1053 132. 98. Contact Lens Applications in Corneal Disease - p. 1054.e1 133. 99. Complications of Contact Lens Wear - p. 1067.e1 134. The Sclera and Anterior Uvea - p. 1078 135. SECTION 1. Disorders of the Sclera - p. 1078 136. 100. Episcleritis - p. 1079.e1 137. 101. Scleritis - p. 1086.e1 138. SECTION 2. Anterior Uveitis - p. 1098 139. 102. Classification and Diagnosis of Anterior Uveitis - p. 1099.e1 140. 103. Idiopathic Anterior Uveitis - p. 1108.e1 141. 104. HLA-B27–Associated Uveitis - p. 1117.e1 142. 105. Sarcoidosis - p. 1122.e1 143. 106. Behçet Disease - p. 1128.e1 144. 107. Fuchs Uveitis Syndrome - p. 1136.e1 145. 108. Juvenile Idiopathic Arthritis-Associated Uveitis - p. 1140.e1 146. Keratoplasty - p. 1146 147. SECTION 1. Overview - p. 1146 148. 109. The Evolution of Contemporary Keratoplasty - p. 1147.e1 149. 110. Preoperative Considerations and Decision-Making in Keratoplasty - p. 1155.e1 150. SECTION 2. Penetrating Keratoplasty Procedures - p. 1161 151. 111. Penetrating Keratoplasty: The Fundamentals - p. 1162.e1 152. 112. Intraoperative Complications of Penetrating Keratoplasty - p. 1174.e1 153. 113. Femtosecond-Assisted Penetrating Keratoplasty - p. 1180.e1 154. SECTION 3. Penetrating Keratoplasty: Postoperative Management - p. 1186.e1 155. 114. Postoperative Management - p. 1187.e1 156. 115. Diagnosis and Management of Corneal Allograft Rejection - p. 1207.e1 157. 116. Infections After Penetrating Keratoplasty - p. 1215.e1 158. 117. Glaucoma After Corneal Transplantation - p. 1228.e1 159. SECTION 4. Anterior Lamellar Keratoplasty - p. 1241 160. 118. Indications for Anterior Lamellar Keratoplasty - p. 1242.e1 161. 119. Historical Development of Anterior Lamellar Keratoplasty - p. 1250.e1 162. 120. Techniques of Anterior Lamellar Keratoplasty - p. 1256.e1 163. 121. Intraoperative and Postoperative Complications of Anterior Lamellar Keratoplasty - p. 1263.e1 164. 122. Recovery Techniques in Deep Anterior Lamellar Keratoplasty - p. 1267.e1 165. 123. Outcomes of Anterior Lamellar Keratoplasty - p. 1273.e1 166. SECTION 5. Complex Keratoplasty - p. 1276 167. 124. Pediatric Keratoplasty - p. 1277.e1 168. 125. Keratoplasty in Herpes Simplex Infection - p. 1295.e1 169. 126. Immunologically High-Risk Penetrating Keratoplasty and Large-Diameter Corneal Grafts - p. 1305.e1 170. SECTION 6. Endothelial Keratoplasty - p. 1322 171. 127. Historical Development of Endothelial Keratoplasty - p. 1323.e1 172. 128. Indications and Decision-Making for Endothelial Keratoplasty - p. 1328.e1 173. 129. Eye Bank Preparation of Tissue for Endothelial Keratoplasty - p. 1333.e1 174. 130. Surgical Techniques for Descemet Stripping Automated Endothelial Keratoplasty - p. 1341.e1 175. 131. Ultrathin Descemet Stripping Automated Endothelial Keratoplasty - p. 1351.e1 176. 132. Nanothin Descemet Stripping Automated Endothelial Keratoplasty - p. 1358.e1 177. 133. Intraoperative and Postoperative Complications of Descemet Stripping Automated Endothelial Keratoplasty - p. 1363.e1 178. 134. Outcomes of Descemet Stripping Automated Endothelial Keratoplasty - p. 1369.e1 179. 135. Surgical Technique for Descemet Membrane Endothelial Keratoplasty - p. 1374.e1 180. 136. Intraoperative and Postoperative Complications of Descemet Membrane Endothelial Keratoplasty - p. 1387.e1 181. 137. Outcomes of Descemet Membrane Endothelial Keratoplasty - p. 1392.e1 182. 138. Complex Endothelial Keratoplasty - p. 1403.e1 183. 139. Cultivated Corneal Endothelial Cell Transplantation - p. 1410.e1 184. Therapeutic Procedures - p. 1413 185. SECTION 1. Corneal Surgery - p. 1413 186. 140. Management of Corneal Perforations - p. 1414.e1 187. 141. Therapeutic Keratoplasty - p. 1431.e1 188. 142. Surgical Management of Superficial Corneal and Conjunctival Disease - p. 1445.e1 189. 143. Excimer Laser Phototherapeutic Keratectomy - p. 1455.e1 190. SECTION 2. Conjunctival Surgery - p. 1466.e1 191. Management of Primary Pterygium - p. 1467.e1 192. 145. Management of Recurrent Pterygium - p. 1480.e1 193. 146. Conjunctival Flaps - p. 1489.e1 194. 147. Indications for and Uses of Amniotic Membrane: Clinic - p. 1497.e1 195. 148. Indications for and Uses of Amniotic Membrane: Operating Room - p. 1501.e1 196. SECTION 3. Anterior Segment Surgery - p. 1507.e1 197. 149. Surgical Management and Rehabilitation of Anterior Segment Trauma - p. 1508.e1 198. 150. Iris Reconstruction Surgery - p. 1522.e1 199. 151. Management of Scleral Perforation - p. 1531.e1 200. PART XI. Collagen Crosslinking - p. 1538 201. 152. Collagen Crosslinking for Keratoconus - p. 1539.e1 202. 153. Collagen Crosslinking for Postrefractive Ectasia - p. 1547.e1 203. 154. Collagen Crosslinking for Infectious Keratitis - p. 1553.e1 204. PART XII. Keratoprosthesis - p. 1557 205. 155. Indications for Keratoprosthesis - p. 1558.e1 206. 156. Boston Keratoprosthesis Type 1 Surgical Technique - p. 1562.e1 207. 157. Postoperative Management of Boston Keratoprosthesis Type 1 - p. 1567.e1 208. 158. Complications of Boston Keratoprosthesis Type 1 - p. 1573.e1 209. 159. Outcomes of Boston Keratoprosthesis Type 1 - p. 1578.e1 210. 160. Boston Keratoprosthesis Type 2 Surgical Techniques, Complications, and Outcomes - p. 1582.e1 211. 161. Osteo-Odonto-Keratoprosthesis - p. 1586.e1 212. 162. Contemporary Approaches to the Biosynthetic Cornea: Overview and Classification - p. 1591.e1 213. PART XIII. Ocular Surface Transplantation - p. 1593 214. 163. Classification and Staging of Ocular Surface Disease - p. 1594.e1 215. 164. Conjunctival Limbal Autograft 1 - p. 1607.e1 216. 165. Living-Related Conjunctival Limbal Allograft - p. 1615.e1 217. 166. Keratolimbal Allograft - p. 1623.e1 218. 167. Cultivated Limbal Epithelial Transplant - p. 1629.e1 219. 168. Simple Limbal Epithelial Transplantation - p. 1634.e1 220. 169. Postoperative Management of Ocular Surface Reconstruction - p. 1639.e1 221. 170. Corneal Transplantation in Ocular Surface Disease - p. 1649.e1 222. 171. Outcomes of Ocular Surface Transplantation - p. 1653.e1 223. Refractive Surgery - p. 1659 224. SECTION 1. Preoperative Considerations - p. 1659 225. 172. Decision-Making in Refractive Surgery - p. 1660.e1 226. 173. Patient Evaluation and Selection in Refractive Surgery - p. 1666.e1 227. 174. Topographic Analysis in Keratorefractive Surgery - p. 1674.e1 228. SECTION 2. Laser Vision Correction - p. 1681 229. 175. Excimer Laser Surface Treatment: Photorefractive Keratectomy - p. 1682.e1 230. 176. LASIK Technique - p. 1695.e1 231. 177. LASIK for Myopia - p. 1707.e1 232. 178. LASIK for Hyperopia - p. 1718.e1 233. 179. LASIK Complications - p. 1725.e1 234. 180. Corneal Ectasia: Prevention, Detection, and Management - p. 1742.e1 235. 181. Small-Incision Lenticule Extraction - p. 1752.e1 236. SECTION 3. Additional Refractive Procedures - p. 1756.e1 237. 182. Topography-Guided Photorefractive Keratectomy - p. 1757.e1 238. 183. Intrastromal Corneal Ring Segments - p. 1765.e1 239. 184. Combined Corneal Refractive Techniques - p. 1778.e1 240. 185. Incisional Keratotomy - p. 1784.e1 241. 186. Phakic Intraocular Lenses - p. 1795.e1 242. 187. Corneal Inlay Surgery for Presbyopia: Techniques and Complications - p. 1801.e1 243. Index - p. 1
The only reference available that synthesizes this vast subspecialty into a single trustworthy resource, Cornea, 5th Edition, provides state-of-the-art coverage of the expanding range of contemporary corneal surgery, new diagnostic and imaging technologies, and medical management of corneal and external disease as well as ocular surface disease. Drs. Mark J. Mannis, Edward J. Holland, and a team of more than 200 global experts keep you up to date with both common and more obscure diseases and disorders and the best route to effective treatment and management, making this two-volume text a must-have resource for residents and fellows, general ophthalmologists, and seasoned cornea specialists.
Features more than 2,300 exceptionally clear illustrations, diagnostic images, and step-by-step surgical photographs that offer superb visual guidance.
Contains 14 new chapters, including Nanothin DSAEK, Aqueous Deficiency Dry Eye Syndrome, Evaluation of Recurrent Corneal Erosions, Evaluation of the Corneal Ulcer, Contemporary Approaches to the Biosynthetic Cornea, and Topography Guided Photorefractive Keratectomy, and more.
Includes more than 80 video clips of current corneal surgery techniques, including new clips of the application of cryopreserved amniotic membrane in the treatment of acute stevens, penetrating keratoplasty, DM rupture management in STALK and in the keratonconus patient, and KAMRA corneal inlay implantation.
Covers the latest developments in ocular surface transplantation, including new chapters on Conjunctival Limbal Autograft (CLAU); Living Related Conjunctival Limbal Allograft (Lr-CLAL); Keratolimbal Allograft; Cultivated Limbal Epithelial Transplantation; Simple Limbal Epithelial Transplantation; and Outcomes of Ocular Surface Transplantation.
Provides key point overviews in each chapter that offer easier access to crucial information.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Preface - p. xiii 6. Acknowledgments - p. xiv 7. Dedication - p. xv 8. Acknowledgments to the Founding Editors - p. xvi 9. List of Contributors - p. xvii 10. Videos - p. xxix 11. PART I. Basic Science: Cornea, Sclera, Ocular Adnexa Anatomy, Physiology, and Pathophysiologic Responses - p. xxix 12. 1. Cornea and Sclera: Anatomy and Physiology - p. 1.e1 13. 2. The Conjunctiva: Anatomy and Physiology - p. 23.e1 14. 3. Tear Film - p. 31.e1 15. 4. Eyelids and the Corneal Surface - p. 40.e1 16. 5. A Matrix of Pathologic Responses in the Cornea - p. 45.e1 17. Examining and Imaging the Cornea and External Eye - p. 45.e23 18. SECTION 1. Basic Evaluation of the Cornea and External Eye - p. 45.e23 19. 6. Examination of the Lids - p. 46.e1 20. 7. Slit Lamp Examination and Photography - p. 53.e1 21. 8. Tear Film and Corneal Diagnostic Techniques - p. 81.e1 22. SECTION 2. Laboratory Investigations - p. 89 23. 9. Practical Ophthalmic Microbiology for the Detection of Corneal Pathogens - p. 90.e1 24. 10. Molecular Genetics of Corneal Disease - p. 99.e1 25. SECTION 3. Imaging Techniques of the Cornea - p. 110 26. 11. Keratometry and Topography - p. 111.e1 27. 12. Corneal Shape Analysis and Biomechanical Assessment - p. 124.e1 28. 13. Specular Microscopy - p. 130.e1 29. 14. Confocal Microscopy - p. 152.e1 30. 15. Clinical Applications of Confocal Microscopy - p. 162.e1 31. 16. High-Resolution Ultrasound - p. 171.e1 32. 17. Anterior Segment Optical Coherence Tomography - p. 179.e1 33. PART III. Differential Diagnosis of Selected Problems in Cornea and External Eye Disease - p. 184 34. 18. Congenital Corneal Opacities: Diagnosis and Management - p. 185.e1 35. 19. Peripheral Corneal Disease - p. 209.e1 36. 20. Evaluation of the Corneal Ulcer - p. 218.e1 37. 21. Evaluation of Recurrent Corneal Erosions - p. 222.e1 38. 22. Corneal Deposits - p. 226.e1 39. 23. The Red Eye - p. 239.e1 40. PART IV. Eye Banking - p. 245 41. 24. Eye Banking: Structure and Function - p. 246.e1 42. 25. Medical Standards for Eye Banking - p. 250.e1 43. The Ocular Adnexa - p. 258 44. SECTION 1. Diseases of the Lid: Anatomic Abnormalities - p. 258 45. 26. Malposition of the Eyelids - p. 259.e1 46. SECTION 2. Diseases of the Lid: Tumors, Inflammation, and Infection - p. 275 47. 27. Benign Lid Tumors - p. 276.e1 48. 28. Malignant Eyelid Tumors - p. 294.e1 49. 29. Blepharitis: Overview and Classification - p. 308.e1 50. 30. Eyelid Infections - p. 312.e1 51. SECTION 3. Disorders of Tear Production and the Lacrimal System - p. 320 52. 31. Dry Eye Overview: Classification and Treatment Algorithm - p. 321.e1 53. 32. Aqueous Deficiency Dry Eye Syndrome - p. 329.e1 54. 33. Meibomian Gland Dysfunction and Evaporative Dry Eye - p. 336.e1 55. 34. Dacryoadenitis, Dacryocystitis, and Canaliculitis - p. 345.e1 56. 35. Epiphora - p. 352.e1 57. The Conjunctiva - p. 357 58. SECTION 1. Conjunctivitis - p. 357 59. 36. Conjunctivitis: An Overview and Classification - p. 358.e1 60. 37. Bacterial Conjunctivitis - p. 370.e1 61. 38. Viral Conjunctivitis - p. 377.e1 62. 39. Chlamydial Infections - p. 386.e1 63. 40. Ophthalmia Neonatorum - p. 394.e1 64. 41. Parinaud Oculoglandular Syndrome - p. 400.e1 65. 42. Seasonal and Perennial Allergic Conjunctivitis - p. 407.e1 66. 43. Vernal and Atopic Keratoconjunctivitis - p. 413.e1 67. 44. Giant Papillary Conjunctivitis - p. 421.e1 68. 45. Mucous Membrane Pemphigoid - p. 427.e1 69. 46. Erythema Multiforme, Stevens-Johnson Syndrome, and Toxic Epidermal Necrolysis - p. 435.e1 70. 47. Toxic Conjunctivitis - p. 450.e1 71. 48. Superior Limbic Keratoconjunctivitis - p. 458.e1 72. 49. Ligneous Conjunctivitis - p. 465.e1 73. 50. Conjunctivochalasis - p. 471.e1 74. SECTION 2. Conjunctival Disease: Tumors - p. 477 75. 51. Epithelial Tumors of the Conjunctiva - p. 478.e1 76. 52. Medical and Surgical Management of Ocular Surface Squamous Neoplasia - p. 497.e1 77. 53. Melanocytic Neoplasms of the Conjunctiva - p. 507.e1 78. 54. Subepithelial Tumors of the Conjunctiva - p. 516.e1 79. Diseases of the Cornea - p. 539 80. SECTION 1. Developmental Abnormalities of Cornea - p. 539 81. 55. Developmental Corneal Anomalies of Size and Shape - p. 540.e1 82. 56. Axenfeld-Rieger Syndrome - p. 551.e1 83. 57. Peters Anomaly - p. 558.e1 84. SECTION 2. Corneal Manifestations of Systemic Disease and Therapies - p. 560 85. 58. Corneal Manifestations of Metabolic Diseases - p. 561.e1 86. 59. Skeletal and Connective Tissue Disorders With Anterior Segment Manifestations - p. 586.e1 87. 60. Granulomatosis With Polyangiitis and Other Systemic Inflammatory Diseases - p. 603.e1 88. 61. Nutritional Disorders - p. 613.e1 89. 62. Hematologic Diseases and Malignancies - p. 624.e1 90. 63. Endocrine Disease and the Cornea - p. 631.e1 91. 64. Dermatologic Disorders and the Cornea - p. 640.e1 92. 65. Infectious Disease: Ocular Manifestations - p. 653.e1 93. 66. Corneal and External Ocular Infections in Acquired Immunodeficiency Syndrome - p. 664.e1 94. 67. Ocular Graft-Versus-Host Disease - p. 673.e1 95. 68. Corneal Manifestations of Local and Systemic Therapies - p. 686.e1 96. SECTION 3. Corneal Dystrophies, Ectatic Disorders, and Degenerations - p. 695 97. 69. Corneal Dystrophy Classification - p. 696.e1 98. 70. Anterior Corneal Dystrophies - p. 701.e1 99. 71. The Stromal Dystrophies - p. 712.e1 100. 72. Descemet Membrane and Endothelial Dystrophies - p. 730.e1 101. 73. Noninflammatory Ectatic Disorders - p. 749.e1 102. 74. Iridocorneal Endothelial Syndrome - p. 771.e1 103. 75. Corneal and Conjunctival Degenerations - p. 784.e1 104. SECTION 4. Corneal Infections - p. 801 105. 76. Bacterial Keratitis - p. 802.e1 106. 77. Nontuberculous Mycobacteria Keratitis - p. 825.e1 107. 78. Herpes Simplex Keratitis - p. 832.e1 108. 79. Herpes Zoster Keratitis - p. 861.e1 109. 80. Less Common Viral Corneal Infections - p. 873.e1 110. 81. Fungal Keratitis - p. 880.e1 111. Acanthamoeba and Other Parasitic Corneal Infections - p. 896.e1 112. 83. Corneal Diseases in the Developing World - p. 907.e1 113. SECTION 5. Interstitial Keratitis - p. 916 114. 84. Syphilitic Keratitis - p. 917.e1 115. 85. Nonsyphilitic Interstitial Keratitis - p. 927.e1 116. SECTION 6. Noninfectious Keratopathy - p. 937 117. 86. Filamentary Keratitis - p. 938.e1 118. 87. Superficial Punctate Keratitis of Thygeson - p. 942.e1 119. 88. Neurotrophic Keratitis - p. 946.e1 120. 89. Factitious Keratoconjunctivitis - p. 954.e1 121. SECTION 7. Immunologic Disorders of the Cornea - p. 960 122. 90. Corneal Disease in Rheumatoid Arthritis - p. 961.e1 123. 91. Corneal Disease Associated With Nonrheumatoid Collagen-Vascular Disease - p. 974.e1 124. 92. Phlyctenular Keratoconjunctivitis and Marginal Staphylococcal Keratitis - p. 984.e1 125. 93. Mooren Ulcer - p. 990.e1 126. SECTION 8. Corneal Trauma - p. 995 127. 94. Mechanical Injury - p. 996.e1 128. 95. Chemical and Thermal Injuries of the Eye - p. 1012.e1 129. 96. Corneal Complications of Intraocular Surgery - p. 1024.e1 130. 97. External Eye Manifestations of Biological and Chemical Warfare - p. 1042.e1 131. SECTION 9. Contact Lenses - p. 1053 132. 98. Contact Lens Applications in Corneal Disease - p. 1054.e1 133. 99. Complications of Contact Lens Wear - p. 1067.e1 134. The Sclera and Anterior Uvea - p. 1078 135. SECTION 1. Disorders of the Sclera - p. 1078 136. 100. Episcleritis - p. 1079.e1 137. 101. Scleritis - p. 1086.e1 138. SECTION 2. Anterior Uveitis - p. 1098 139. 102. Classification and Diagnosis of Anterior Uveitis - p. 1099.e1 140. 103. Idiopathic Anterior Uveitis - p. 1108.e1 141. 104. HLA-B27–Associated Uveitis - p. 1117.e1 142. 105. Sarcoidosis - p. 1122.e1 143. 106. Behçet Disease - p. 1128.e1 144. 107. Fuchs Uveitis Syndrome - p. 1136.e1 145. 108. Juvenile Idiopathic Arthritis-Associated Uveitis - p. 1140.e1 146. Keratoplasty - p. 1146 147. SECTION 1. Overview - p. 1146 148. 109. The Evolution of Contemporary Keratoplasty - p. 1147.e1 149. 110. Preoperative Considerations and Decision-Making in Keratoplasty - p. 1155.e1 150. SECTION 2. Penetrating Keratoplasty Procedures - p. 1161 151. 111. Penetrating Keratoplasty: The Fundamentals - p. 1162.e1 152. 112. Intraoperative Complications of Penetrating Keratoplasty - p. 1174.e1 153. 113. Femtosecond-Assisted Penetrating Keratoplasty - p. 1180.e1 154. SECTION 3. Penetrating Keratoplasty: Postoperative Management - p. 1186.e1 155. 114. Postoperative Management - p. 1187.e1 156. 115. Diagnosis and Management of Corneal Allograft Rejection - p. 1207.e1 157. 116. Infections After Penetrating Keratoplasty - p. 1215.e1 158. 117. Glaucoma After Corneal Transplantation - p. 1228.e1 159. SECTION 4. Anterior Lamellar Keratoplasty - p. 1241 160. 118. Indications for Anterior Lamellar Keratoplasty - p. 1242.e1 161. 119. Historical Development of Anterior Lamellar Keratoplasty - p. 1250.e1 162. 120. Techniques of Anterior Lamellar Keratoplasty - p. 1256.e1 163. 121. Intraoperative and Postoperative Complications of Anterior Lamellar Keratoplasty - p. 1263.e1 164. 122. Recovery Techniques in Deep Anterior Lamellar Keratoplasty - p. 1267.e1 165. 123. Outcomes of Anterior Lamellar Keratoplasty - p. 1273.e1 166. SECTION 5. Complex Keratoplasty - p. 1276 167. 124. Pediatric Keratoplasty - p. 1277.e1 168. 125. Keratoplasty in Herpes Simplex Infection - p. 1295.e1 169. 126. Immunologically High-Risk Penetrating Keratoplasty and Large-Diameter Corneal Grafts - p. 1305.e1 170. SECTION 6. Endothelial Keratoplasty - p. 1322 171. 127. Historical Development of Endothelial Keratoplasty - p. 1323.e1 172. 128. Indications and Decision-Making for Endothelial Keratoplasty - p. 1328.e1 173. 129. Eye Bank Preparation of Tissue for Endothelial Keratoplasty - p. 1333.e1 174. 130. Surgical Techniques for Descemet Stripping Automated Endothelial Keratoplasty - p. 1341.e1 175. 131. Ultrathin Descemet Stripping Automated Endothelial Keratoplasty - p. 1351.e1 176. 132. Nanothin Descemet Stripping Automated Endothelial Keratoplasty - p. 1358.e1 177. 133. Intraoperative and Postoperative Complications of Descemet Stripping Automated Endothelial Keratoplasty - p. 1363.e1 178. 134. Outcomes of Descemet Stripping Automated Endothelial Keratoplasty - p. 1369.e1 179. 135. Surgical Technique for Descemet Membrane Endothelial Keratoplasty - p. 1374.e1 180. 136. Intraoperative and Postoperative Complications of Descemet Membrane Endothelial Keratoplasty - p. 1387.e1 181. 137. Outcomes of Descemet Membrane Endothelial Keratoplasty - p. 1392.e1 182. 138. Complex Endothelial Keratoplasty - p. 1403.e1 183. 139. Cultivated Corneal Endothelial Cell Transplantation - p. 1410.e1 184. Therapeutic Procedures - p. 1413 185. SECTION 1. Corneal Surgery - p. 1413 186. 140. Management of Corneal Perforations - p. 1414.e1 187. 141. Therapeutic Keratoplasty - p. 1431.e1 188. 142. Surgical Management of Superficial Corneal and Conjunctival Disease - p. 1445.e1 189. 143. Excimer Laser Phototherapeutic Keratectomy - p. 1455.e1 190. SECTION 2. Conjunctival Surgery - p. 1466.e1 191. Management of Primary Pterygium - p. 1467.e1 192. 145. Management of Recurrent Pterygium - p. 1480.e1 193. 146. Conjunctival Flaps - p. 1489.e1 194. 147. Indications for and Uses of Amniotic Membrane: Clinic - p. 1497.e1 195. 148. Indications for and Uses of Amniotic Membrane: Operating Room - p. 1501.e1 196. SECTION 3. Anterior Segment Surgery - p. 1507.e1 197. 149. Surgical Management and Rehabilitation of Anterior Segment Trauma - p. 1508.e1 198. 150. Iris Reconstruction Surgery - p. 1522.e1 199. 151. Management of Scleral Perforation - p. 1531.e1 200. PART XI. Collagen Crosslinking - p. 1538 201. 152. Collagen Crosslinking for Keratoconus - p. 1539.e1 202. 153. Collagen Crosslinking for Postrefractive Ectasia - p. 1547.e1 203. 154. Collagen Crosslinking for Infectious Keratitis - p. 1553.e1 204. PART XII. Keratoprosthesis - p. 1557 205. 155. Indications for Keratoprosthesis - p. 1558.e1 206. 156. Boston Keratoprosthesis Type 1 Surgical Technique - p. 1562.e1 207. 157. Postoperative Management of Boston Keratoprosthesis Type 1 - p. 1567.e1 208. 158. Complications of Boston Keratoprosthesis Type 1 - p. 1573.e1 209. 159. Outcomes of Boston Keratoprosthesis Type 1 - p. 1578.e1 210. 160. Boston Keratoprosthesis Type 2 Surgical Techniques, Complications, and Outcomes - p. 1582.e1 211. 161. Osteo-Odonto-Keratoprosthesis - p. 1586.e1 212. 162. Contemporary Approaches to the Biosynthetic Cornea: Overview and Classification - p. 1591.e1 213. PART XIII. Ocular Surface Transplantation - p. 1593 214. 163. Classification and Staging of Ocular Surface Disease - p. 1594.e1 215. 164. Conjunctival Limbal Autograft 1 - p. 1607.e1 216. 165. Living-Related Conjunctival Limbal Allograft - p. 1615.e1 217. 166. Keratolimbal Allograft - p. 1623.e1 218. 167. Cultivated Limbal Epithelial Transplant - p. 1629.e1 219. 168. Simple Limbal Epithelial Transplantation - p. 1634.e1 220. 169. Postoperative Management of Ocular Surface Reconstruction - p. 1639.e1 221. 170. Corneal Transplantation in Ocular Surface Disease - p. 1649.e1 222. 171. Outcomes of Ocular Surface Transplantation - p. 1653.e1 223. Refractive Surgery - p. 1659 224. SECTION 1. Preoperative Considerations - p. 1659 225. 172. Decision-Making in Refractive Surgery - p. 1660.e1 226. 173. Patient Evaluation and Selection in Refractive Surgery - p. 1666.e1 227. 174. Topographic Analysis in Keratorefractive Surgery - p. 1674.e1 228. SECTION 2. Laser Vision Correction - p. 1681 229. 175. Excimer Laser Surface Treatment: Photorefractive Keratectomy - p. 1682.e1 230. 176. LASIK Technique - p. 1695.e1 231. 177. LASIK for Myopia - p. 1707.e1 232. 178. LASIK for Hyperopia - p. 1718.e1 233. 179. LASIK Complications - p. 1725.e1 234. 180. Corneal Ectasia: Prevention, Detection, and Management - p. 1742.e1 235. 181. Small-Incision Lenticule Extraction - p. 1752.e1 236. SECTION 3. Additional Refractive Procedures - p. 1756.e1 237. 182. Topography-Guided Photorefractive Keratectomy - p. 1757.e1 238. 183. Intrastromal Corneal Ring Segments - p. 1765.e1 239. 184. Combined Corneal Refractive Techniques - p. 1778.e1 240. 185. Incisional Keratotomy - p. 1784.e1 241. 186. Phakic Intraocular Lenses - p. 1795.e1 242. 187. Corneal Inlay Surgery for Presbyopia: Techniques and Complications - p. 1801.e1 243. Index - p. 1
