Annual Reports in Medicinal Chemistry, Volume 57 in this long-running series, highlights new advances in the field with this new volume presenting interesting chapters on the Mechanism of action of the broadly acting antiviral drug remdesivir, Improving properties of the nucleobase analogue T-706 as a potential anti-SARS-CoV-2 and anti-influenza compound, Antivirals for RNA virus infections Anno 2020-2021, Broad spectrum antiviral fleximer nucleosides, SARS-CoV-2 main protease inhibitors, The search for antivirals to treat alphavirus infections, Inhibitors of Ebola Virus targeting Innate immune evasion, Uracil derivatives as non-nucleoside inhibitors of viral infections, and more.
1. Cover image - p. i 2. Table of Contents - p. iii 3. Series Page - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. xi 7. Chapter One: Improving properties of the nucleobase analogs T-705/T-1105 as potential antiviral - p. 1 8. Chapter Two: Anno 2021: Which antivirals for the coming decade? - p. 49 9. Chapter Three: Broad spectrum antiviral nucleosides—Our best hope for the future - p. 109 10. Chapter Four: The search for antivirals to treat alphavirus infections - p. 133 11. Chapter Five: Inhibitors of Ebolavirus targeting innate immune evasion - p. 153 12. Chapter Six: Uracil derivatives as non-nucleoside inhibitors of viral infections - p. 175
Annual Reports in Medicinal Chemistry, Volume 57 in this long-running series, highlights new advances in the field with this new volume presenting interesting chapters on the Mechanism of action of the broadly acting antiviral drug remdesivir, Improving properties of the nucleobase analogue T-706 as a potential anti-SARS-CoV-2 and anti-influenza compound, Antivirals for RNA virus infections Anno 2020-2021, Broad spectrum antiviral fleximer nucleosides, SARS-CoV-2 main protease inhibitors, The search for antivirals to treat alphavirus infections, Inhibitors of Ebola Virus targeting Innate immune evasion, Uracil derivatives as non-nucleoside inhibitors of viral infections, and more.
1. Cover image - p. i 2. Table of Contents - p. iii 3. Series Page - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. xi 7. Chapter One: Improving properties of the nucleobase analogs T-705/T-1105 as potential antiviral - p. 1 8. Chapter Two: Anno 2021: Which antivirals for the coming decade? - p. 49 9. Chapter Three: Broad spectrum antiviral nucleosides—Our best hope for the future - p. 109 10. Chapter Four: The search for antivirals to treat alphavirus infections - p. 133 11. Chapter Five: Inhibitors of Ebolavirus targeting innate immune evasion - p. 153 12. Chapter Six: Uracil derivatives as non-nucleoside inhibitors of viral infections - p. 175
