Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C, Volume 183 represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this volume include discussions on the evolution of disorder, consideration of the peculiarities of phase separation of the prion protein, a general discussion of the relationships between intrinsic disorder and protein functions, coverage of the structural and functional characterization of several important intrinsically disordered proteins, such as transcription factors, outer membrane porins, trans-membrane and membrane associated proteins with ID regions, discussion of molecular simulations of IDPs, and much more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface: The Patchwork Quilt of Intrinsic Disorder - p. xiii 7. Chapter One: Intrinsic disorder and phase transitions: Pieces in the puzzling role of the prion protein in health and disease - p. 25 8. Chapter Two: Functions of intrinsically disordered proteins through evolutionary lenses - p. 45 9. Chapter Three: Non-specific porins of Gram-negative bacteria as proteins containing intrinsically disordered regions with amyloidogenic potential - p. 75 10. Chapter Four: Intrinsic disorder in integral membrane proteins - p. 101 11. Chapter Five: Molecular simulations of IDPs: From ensemble generation to IDP interactions leading to disorder-to-order transitions - p. 135 12. Chapter Six: Target-binding behavior of IDPs via pre-structured motifs - p. 200 13. Chapter Seven: The role of dancing duplexes in biology and disease - p. 249 14. Chapter Eight: Intrinsic disorder in protein kinase A anchoring proteins signaling complexes - p. 271 15. Chapter Nine: Protein intrinsic disorder on a dynamic nucleosomal landscape - p. 295 16. Chapter Ten: Flexible spandrels of the global plant virome: Proteomic-wide evolutionary patterns of structural intrinsic protein disorder elucidate modulation at the functional virus–host interplay - p. 368 17. Index - p. 409
Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C, Volume 183 represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this volume include discussions on the evolution of disorder, consideration of the peculiarities of phase separation of the prion protein, a general discussion of the relationships between intrinsic disorder and protein functions, coverage of the structural and functional characterization of several important intrinsically disordered proteins, such as transcription factors, outer membrane porins, trans-membrane and membrane associated proteins with ID regions, discussion of molecular simulations of IDPs, and much more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface: The Patchwork Quilt of Intrinsic Disorder - p. xiii 7. Chapter One: Intrinsic disorder and phase transitions: Pieces in the puzzling role of the prion protein in health and disease - p. 25 8. Chapter Two: Functions of intrinsically disordered proteins through evolutionary lenses - p. 45 9. Chapter Three: Non-specific porins of Gram-negative bacteria as proteins containing intrinsically disordered regions with amyloidogenic potential - p. 75 10. Chapter Four: Intrinsic disorder in integral membrane proteins - p. 101 11. Chapter Five: Molecular simulations of IDPs: From ensemble generation to IDP interactions leading to disorder-to-order transitions - p. 135 12. Chapter Six: Target-binding behavior of IDPs via pre-structured motifs - p. 200 13. Chapter Seven: The role of dancing duplexes in biology and disease - p. 249 14. Chapter Eight: Intrinsic disorder in protein kinase A anchoring proteins signaling complexes - p. 271 15. Chapter Nine: Protein intrinsic disorder on a dynamic nucleosomal landscape - p. 295 16. Chapter Ten: Flexible spandrels of the global plant virome: Proteomic-wide evolutionary patterns of structural intrinsic protein disorder elucidate modulation at the functional virus–host interplay - p. 368 17. Index - p. 409
