For more than 40 years, DiSaia and Creasman Clinical Gynecologic Oncology has been the leading reference for diagnosis and treatment of gynecologic cancers, providing physicians and trainees alike with expert guidance on clinical presentations and management. The fully revised 10th Edition remains the most readable, most comprehensive text in the field. Under outstanding editorial leadership from Dr. William Creasman and featuring a “who’s who list of expert contributing authors, this authoritative reference is a must-have resource for improving outcomes and providing effective patient care.
Emphasizes practical clinical presentations and management of commonly seen problems, making this text an excellent resource for daily decision making.
Provides in-depth explanations of major topics supplemented with up-to-date references.
Features a new chapter on Immunotherapy in Gynecologic Malignancies, updated information on invasive cervical cancer, and significantly revised content on vulvar cancer, with new guidance on micro-staging for sentinels and updates from GOG 173 and the GROINS VII study.
Covers key topics such as precision medicine and new biomarker-driven targeted therapies, cancer staging, targeted therapy, and immunotherapy.
Includes quick-reference features such as key point boxes with bulleted lists, highlighted key text, enhanced chapter outlines, clinical algorithms that review recommended treatment and management options, and additional references online.
Contains useful appendices covering staging, screening, nutritional therapy, toxicity criteria, blood component therapy, and radiation therapy.
An ideal comprehensive resource for clinical practice, personal study, and exam review.
1. Introduction - p. 311 2. Anatomy of the breast - p. 311 3. Embryology and development of the breast - p. 313 4. Pregnancy and breast feeding - p. 314 5. Benign breast conditions - p. 314 6. History and physical examination - p. 317 7. Breast imaging - p. 319 8. Breast ultrasound and magnetic resonance imaging - p. 322 9. Diagnostic evaluation - p. 323 10. Epidemiology of breast cancer - p. 325 11. Risk factors and assessment - p. 325 12. Pathology - p. 327 13. Metastases from extramammary tumors - p. 329 14. Biologic markers and prognostic factors - p. 329 15. Staging of breast cancer using the tumor–node–metastasis system - p. 330 16. Treatment of breast cancer - p. 332 17. Special issues - p. 340 18. Conclusions - p. 343 19. Bibliography - p. 344 20. 12. Cancer in pregnancy - p. 345 21. Background and epidemiology of cancer - p. 345 22. The more common solid tumors - p. 347 23. Evaluation and therapeutic modalities - p. 378 24. Hematologic malignancies - p. 394 25. Other tumors - p. 402 26. Bibliography - p. 414 27. 13. Complications of disease and therapy - p. 415 28. 14. Basic principles of chemotherapy and other systemic therapies - p. 443 29. 15. Targeted therapy and molecular genetics - p. 464 30. 16. Molecular hallmarks of cancer - p. 489 31. 17. Immunotherapy in gynecologic malignancies - p. 506 32. 18. Genes and cancer: Genetic counselling and clinical management - p. 521 33. Introduction - p. 521 34. Genetic alterations in cancer - p. 523 35. Mechanisms of human gene mutation - p. 524 36. Cancer epigenetics - p. 529 37. Genomic imprinting and cancer - p. 529 38. Genetic alterations that cause cancer - p. 530 39. Hereditary cancer risk assessment: Genetic counseling and genetic testing - p. 537 40. Genetic counseling and genetic testing for hereditary cancers - p. 551 41. Referral of gynecologic cancer patients for hereditary cancer risk assessment - p. 553 42. Genetic testing - p. 554 43. Legal aspects of genetic testing - p. 556 44. Long-term contact for patients and families with hereditary risk for cancer - p. 557 45. DNA banking - p. 557 46. Conclusion - p. 557 47. Glossary - p. 558 48. Bibliography - p. 559 49. 19. Palliative care and quality of life - p. 560 50. Evolution of palliative care - p. 560 51. Quality of life in gynecologic cancers - p. 562 52. Management of common physical symptoms - p. 567 53. Psychosocial and spiritual needs of patients and families - p. 585 54. Management of psychosocial and spiritual distress - p. 586 55. Quality of life issues in advanced and recurrent ovarian cancer - p. 587 56. Quality of life issues in advanced and recurrent uterine and cervical cancer - p. 589 57. End-of-life decision making - p. 591 58. Bibliography - p. 593 59. 20. Role of minimally invasive surgery in gynecologic malignancies - p. 594 60. 21. Epidemiology of commonly used statistical terms, and analysis of clinical studies - p. 615 61. 22. Basic principles in gynecologic radiotherapy - p. 624 62. Appendix A: Staging - p. 646 63. Appendix B: Modified from common terminology criteria for adverse events (CTCAE) - p. 648 64. Appendix C: Blood component therapy - p. 649 65. Appendix D: Suggested recommendations for routine cancer screening - p. 653 66. Appendix E: Normal nutrition - p. 655 67. Index - p. 660
For more than 40 years, DiSaia and Creasman Clinical Gynecologic Oncology has been the leading reference for diagnosis and treatment of gynecologic cancers, providing physicians and trainees alike with expert guidance on clinical presentations and management. The fully revised 10th Edition remains the most readable, most comprehensive text in the field. Under outstanding editorial leadership from Dr. William Creasman and featuring a “who’s who list of expert contributing authors, this authoritative reference is a must-have resource for improving outcomes and providing effective patient care.
Emphasizes practical clinical presentations and management of commonly seen problems, making this text an excellent resource for daily decision making.
Provides in-depth explanations of major topics supplemented with up-to-date references.
Features a new chapter on Immunotherapy in Gynecologic Malignancies, updated information on invasive cervical cancer, and significantly revised content on vulvar cancer, with new guidance on micro-staging for sentinels and updates from GOG 173 and the GROINS VII study.
Covers key topics such as precision medicine and new biomarker-driven targeted therapies, cancer staging, targeted therapy, and immunotherapy.
Includes quick-reference features such as key point boxes with bulleted lists, highlighted key text, enhanced chapter outlines, clinical algorithms that review recommended treatment and management options, and additional references online.
Contains useful appendices covering staging, screening, nutritional therapy, toxicity criteria, blood component therapy, and radiation therapy.
An ideal comprehensive resource for clinical practice, personal study, and exam review.
1. Introduction - p. 311 2. Anatomy of the breast - p. 311 3. Embryology and development of the breast - p. 313 4. Pregnancy and breast feeding - p. 314 5. Benign breast conditions - p. 314 6. History and physical examination - p. 317 7. Breast imaging - p. 319 8. Breast ultrasound and magnetic resonance imaging - p. 322 9. Diagnostic evaluation - p. 323 10. Epidemiology of breast cancer - p. 325 11. Risk factors and assessment - p. 325 12. Pathology - p. 327 13. Metastases from extramammary tumors - p. 329 14. Biologic markers and prognostic factors - p. 329 15. Staging of breast cancer using the tumor–node–metastasis system - p. 330 16. Treatment of breast cancer - p. 332 17. Special issues - p. 340 18. Conclusions - p. 343 19. Bibliography - p. 344 20. 12. Cancer in pregnancy - p. 345 21. Background and epidemiology of cancer - p. 345 22. The more common solid tumors - p. 347 23. Evaluation and therapeutic modalities - p. 378 24. Hematologic malignancies - p. 394 25. Other tumors - p. 402 26. Bibliography - p. 414 27. 13. Complications of disease and therapy - p. 415 28. 14. Basic principles of chemotherapy and other systemic therapies - p. 443 29. 15. Targeted therapy and molecular genetics - p. 464 30. 16. Molecular hallmarks of cancer - p. 489 31. 17. Immunotherapy in gynecologic malignancies - p. 506 32. 18. Genes and cancer: Genetic counselling and clinical management - p. 521 33. Introduction - p. 521 34. Genetic alterations in cancer - p. 523 35. Mechanisms of human gene mutation - p. 524 36. Cancer epigenetics - p. 529 37. Genomic imprinting and cancer - p. 529 38. Genetic alterations that cause cancer - p. 530 39. Hereditary cancer risk assessment: Genetic counseling and genetic testing - p. 537 40. Genetic counseling and genetic testing for hereditary cancers - p. 551 41. Referral of gynecologic cancer patients for hereditary cancer risk assessment - p. 553 42. Genetic testing - p. 554 43. Legal aspects of genetic testing - p. 556 44. Long-term contact for patients and families with hereditary risk for cancer - p. 557 45. DNA banking - p. 557 46. Conclusion - p. 557 47. Glossary - p. 558 48. Bibliography - p. 559 49. 19. Palliative care and quality of life - p. 560 50. Evolution of palliative care - p. 560 51. Quality of life in gynecologic cancers - p. 562 52. Management of common physical symptoms - p. 567 53. Psychosocial and spiritual needs of patients and families - p. 585 54. Management of psychosocial and spiritual distress - p. 586 55. Quality of life issues in advanced and recurrent ovarian cancer - p. 587 56. Quality of life issues in advanced and recurrent uterine and cervical cancer - p. 589 57. End-of-life decision making - p. 591 58. Bibliography - p. 593 59. 20. Role of minimally invasive surgery in gynecologic malignancies - p. 594 60. 21. Epidemiology of commonly used statistical terms, and analysis of clinical studies - p. 615 61. 22. Basic principles in gynecologic radiotherapy - p. 624 62. Appendix A: Staging - p. 646 63. Appendix B: Modified from common terminology criteria for adverse events (CTCAE) - p. 648 64. Appendix C: Blood component therapy - p. 649 65. Appendix D: Suggested recommendations for routine cancer screening - p. 653 66. Appendix E: Normal nutrition - p. 655 67. Index - p. 660
